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What is Starlix and what is it used for?
What is Starlix?
Starlix belongs to a group of medicines called oral antidiabetic agents. What Starlix is used for
Starlix is used to treat patients with type 2 diabetes mellitus. It reduces blood glucose (glucose).
Your doctor will prescribe Starlix with another oral antidiabetic medicine containing metformin.
How Starlix works
Insulin is a substance that is formed by the pancreas. It helps to lower blood sugar levels, especially after a meal. If you have type 2 diabetes, your body may not start to release insulin quickly enough after a meal. Starlix works by stimulating the pancreas to release insulin faster. This helps to control blood sugar after a meal.
Starlix tablets start acting soon after you take them and are quickly removed from the body.
2. What you need to know before you take Starlix
Take all the instructions of your doctor and pharmacist carefully, even if they are different from those in this leaflet.
Do not take Starlix
- if you are allergic to nateglinide or any of the other ingredients of this medicine (listed in section 6).
- if you have type 1 diabetes (ie your body does not form any insulin).
- if you have symptoms of severe hyperglycaemia (too high blood sugar and / or diabetic ketoacidosis), such as excessive thirst, frequent urination, weakness or fatigue, nausea, shortness of breath or confusion.
- if you are known to have a serious liver problem.
- if you are pregnant or planning a pregnancy.
- if you are breast-feeding.
If any of the above applies to you, do not take Starlix and talk to your doctor.
Warnings and precautions
Diabetics sometimes develop symptoms of low blood sugar (so-called hypoglycemia). Some medicines, including Starlix, can also cause symptoms of low blood sugar.
If you have low blood sugar, you may experience dizziness, fainting, hunger, shaking or any of the other signs listed in section 4, Possible Side Effects. If this happens, eat or drink something containing sugar and consult your doctor.
Some people are more likely to develop symptoms of low blood sugar than others. Be careful
- if you are over 65 years of age
- if you are malnourished.
- if you have other illnesses that can cause low blood sugar (eg decreased activity of the pituitary or adrenal gland).
If any of these conditions apply to you, you should monitor your blood sugar more closely.
Watch out for the signs of low blood sugar, especially:
- if you have exercised more than usual.
- if you have consumed alcohol.
Alcohol may worsen blood glucose control, so consult your doctor about alcohol consumption during treatment with Starlix.
Talk to your doctor before taking Starlix
- if you know you have a liver problem.
- if you have a severe kidney problem.
- if you have problems with your medicine.
- if you are going to have surgery.
- if you recently suffered from a fever, you have had an accident or infection. Your treatment may need correction.
If you have lactose intolerance (a type of sugar), talk to your doctor before taking Starlix.
Children and adolescents
Starlix is not recommended in children and adolescents (under 18 years of age) because its effects in this age group have not been studied.
Other medicines and Starlix
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
The amount of Starlix you need may change if you are taking other medicines as they may cause a decrease or increase in your blood sugar.
It is especially important to tell your doctor or pharmacist if you are taking:
- Beta-blockers or ACE inhibitors (angiotensin-converting enzyme inhibitors) (used, for example, to treat high blood pressure or certain heart conditions).
- Diuretics (used to treat high blood pressure).
- Corticosteroids such as prednisone or cortisone (used to treat inflammatory diseases).
- Medicinal product inhibitors such as fluconazole (used to treat infections caused by fungi), gemfibrozil (used to treat dyslipidaemia) or sulfinpyrazone (used to treat chronic gout).
- Anabolic hormones (eg methandrosterolone).
- St John's wort (herb).
- Somatropin (growth hormone).
- Somatostatin analogues such as lanreotide and octreotide (used to treat acromegaly).
- Rifampin (used for example to treat tuberculosis).
- Phenytoin (used, for example, to treat seizures). Your doctor may adjust the dose of these medicines
When to take Starlix?
Take Starlix before a meal. It may be delayed if you take it during a meal or after a meal.
Remove Starlix before the three main meals, usually:
- 1 dose before breakfast
- 1 dose before noon
- 1 dose before dinner
It is best to take it immediately before the meal, but you can take it up to 30 minutes before it is taken.
Do not take the medicine if you do not eat basically. If you miss a meal, skip the Starlix dose and wait for your next meal.
Even if you are taking medicines to treat your diabetes, it is important that you continue to follow the diet and / or physical regimen recommended by your doctor.
How long do you take Starlix?
Continue to take Starlix every day until your doctor tells you to stop. If you take more Starlix than you should
If you accidentally take too many tablets, talk to a doctor immediately. If you experience symptoms of low blood sugar (listed in section 4, Possible Side Effects), eat or drink something containing sugar.
If you feel that you may have a severe hypoglycaemic crisis (which may lead to loss of consciousness or seizure), call for emergency care or make sure someone else has done this for you.
If you forget to take Starlix
If you forget to take the tablet, take the next one before your next meal. Do not take a double dose to make up for the missed dose.
Follow-up during treatment with Starlix
Your doctor will periodically check the amount of Starlix you are taking. It is possible to adjust the dose according to your needs. If you have any questions about Starlix or why this medicine has been prescribed for you, ask your doctor.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.
These side effects may occur at some frequency, according to which they are defined as:
• very common: can affect more than 1 in 10 people
• common: may affect up to 1 in 10 people
• Uncommon: may affect up to 1 in 100 people
• rare: may affect up to 1 in 1,000 people
• very rare: can affect up to 1 in 10,000 people
• Frequency not known: can not be estimated from the available data. The side effects caused by Starlix are usually mild to moderate. Common side effects:
These are symptoms of low blood sugar (hypoglycemia), which are usually mildly pronounced. They include:
• Feeling that your heart beats faster
• desire for vomiting (nausea)
These symptoms can be caused by a lack of food or an excessive dose of any antidiabetic medicine you take. If you experience symptoms of low blood sugar, eat or drink something containing sugar.
Other side effects may include:
• Common: abdominal pain, indigestion, diarrhea, nausea
• Uncommon: vomiting
• Rare: slight liver function abnormalities, allergic reactions (hypersensitivity) such as rash and pruritus
• Very rare: blistering of the skin, affecting the lips, eyes and / or mouth, sometimes with headache, fever and / or diarrhea
If any of the side effects gets serious, tell your doctor or pharmacist. This includes all possible side effects not listed in this leaflet.
5. How to store Starlix?
Keep out of the reach and sight of children. Store in the original package.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiry date refers to the last day of that month. Do not use Starlix packaging that is damaged or has tamper evidence. Store below 30 ° C.
Do not dispose of medicines in the sewers or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
Packaging content and additional information
What does Starlix contain?
- The active substance is nateglinide. Each tablet contains 60, 120 or 180 mg of nateglinide.
- The other ingredients are: lactose monohydrate; microcrystalline cellulose; povidone; croscarmellose sodium; magnesium stearate and silica gel, colloidal anhydrous.
- The tablet coat contains hypromellose; titanium dioxide (E171); talc; macrogol and red (60 and 180 mg tablets) or yellow (120 mg tablets) iron oxide (E172).
What does Starlix look like and what does it contain?
Starlix 60 mg film-coated tablets are pink, round tablets with "STARLIX" marked on one side and "60" on the other.
Starlix 120 mg film-coated tablets are yellow, oval tablets with "STARLIX" marked on one side and "120" on the other.
Starlix 180 mg film-coated tablets are red, elliptical tablets with "STARLIX" marked on one side and "180" on the other.
Each blister contains 12, 24, 30, 60, 84, 120 or 360 tablets. Not all packs may be marketed in your country.
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