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PRAMIPEXOLE 0.18 mg. 30 tablets

Brand: TEVA
Product Code: PRAMIPEXOLE 0.18 mg. 30 tablets
Availability: In Stock
Product viewed: 2791

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WHAT PRAMIPEXOLE IS PRESENTED AND WHAT IT IS USED FOR
Pramipexole  belongs to a group of medicinal products known as dopamine agonists that stimulate dopamine receptors in the brain. Stimulation of dopamine receptors causes nerve impulses in the brain to help control body movements.
Pramipexole is used to treat symptoms of primary Parkinson's disease. It can be used alone or in combination with levodopa.

2. BEFORE YOU TAKE PRAMIPEXOLE
Do not take Pramipexole:

if you are allergic (hypersensitive) to pramipexole or any of the other ingredients of Pramipexole (see section 6, Further information).
Take special care with Pramipexole
Tell your doctor if you have (or have had) or developed symptoms or conditions, especially some of the following:

kidney disease;
hallucinations (you see, hear or feel things that are not there). Most hallucinations are visual;
dyskinesia (eg unnatural, uncontrolled movements of the limbs). If you have advanced Parkinson's disease and you are taking levodopa, you may develop dyskinesia during the administration of Pramipexole 
drowsiness and sudden sleep apnea;
behavioral changes (eg abnormal gambling, intrusive shopping), increased libido (eg increased sexual desire), greedy eating;
psychosis (e.g., comparable to the symptoms of schizophrenia);
impaired vision. During treatment with Pramipexole , you should regularly check your eyes with a specialist;
severe heart or blood vessel disease. You should regularly check your blood pressure, especially at the beginning of treatment. This is imperative to avoid postural hypotension (falling blood pressure).
Children and adolescents
The use of Pramipexole  is not recommended in children or adolescents under the age of 18 years.

Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines, herbal products, dietary supplements or other supplements you have taken without a prescription.
You should avoid taking Pramipexole i with antipsychotic medicines.

Take care if you are taking the following medicines:

cimetidine (for the treatment of excess stomach acid and stomach ulcers);
amantadine (which can be used to treat Parkinson's disease).
If you are taking levodopa, it is recommended that the dose of levodopa be reduced when you start treatment with Pramipexole 
Take care if you are using medicines that soothe you (have a sedative effect) or drink alcohol. In these cases, Pramipexole can impair your ability to drive and operate machinery.

Taking Pramipexole  with food and drink
You should be careful when drinking alcohol during treatment with Pramipexole SES.
Pramipexole can be taken with or without food. Swallow the tablets with water.

Pregnancy and breastfeeding
Tell your doctor if you are pregnant, think you may be pregnant or plan to become pregnant. Your doctor will then discuss with you whether to continue to take Pramipexole .
The effect of Pramipexole  on the unborn child is not known. Therefore, if you are pregnant, do not take Pramipexole  unless the doctor tells you to do so.
Pramipexole should not be used during breast-feeding. Pramipexole can reduce the amount of breast milk. It can also pass through the stern and be accepted by the baby. If the use of Pramipexole is inevitable, breast-feeding should be discontinued.
Ask a doctor or pharmacist before using any medicine.

Driving and using machines
Pramipexole  can cause hallucinations (you see, hear or feel things that are not there). If this is the case with you, do not drive or operate machinery.
Pramipexole  is associated with somnolence and sudden sleep apnea, especially in patients with Parkinson's disease. If you experience such side effects, you should not drive or operate machinery. If you have such a situation, talk to your doctor.

3. HOW TO TAKE PRAMIPEXOL 
Always take Pramipexole  exactly as your doctor has told you. If you do not know, talk to your doctor or pharmacist.
You may take Pramipexole  with or without food. Swallow the tablets with water.
The daily dose is taken divided into three equal doses.

During the first week, the usual dose is 1/2 tablet Pramipexole Sigma 0.18 mg three times a day (equivalent to 0.264 mg daily):
The usual maintenance dose is 1.1 mg per day. Your dose may need to be increased. If necessary, your doctor may increase your dose to a maximum of 3.3 mg per day of pramipexole. A lower maintenance dose of 1/2 tablet of Pramipexole Sigma 0.18 mg three times a day is also possible.

Lowest maintenance dose Highest maintenance dose
Number of tablets 1/2 tablet Pramipexole 0.18 mg three times a day 1 tablet Pramipexole 0.7 mg and 2 tablets Pramipexole 0.18 mg three times a day
Total daily dose (mg) 0.264 3.3
Patients with kidney disease
If you have kidney disease in moderate or severe form, your doctor will prescribe a lower dose. In this case, you will have to take the tablets once or twice a day. If your kidney disease is moderate, the usual starting dose is 1/2 tablet Pramipexole Sigma 0.18 mg twice daily. Kidney disease in severe form, the usual starting dose is only 1/2 tablet of Pramipexole  0.18 mg per day.

If you take more Pramipexole than you should
If you accidentally take too many tablets:

immediately consult your doctor or contact the nearest hospital;
you may start vomiting, feel restless or feel any of the side effects listed in section 4 (Possible side effects).
If you forget to take Pramipexole 
Do not worry. Just skip this dose and then take the next one at the right time. Do not try to make up for the missed dose.

If you stop taking Pramipexole 
Do not stop taking Pramipexole  without consulting your doctor. If you need to stop taking this medicine, your doctor will advise you to gradually lower your dose. This reduces the risk of worsening of the symptoms.

If you suffer from Parkinson's disease, you should not stop taking Pramipexole SESCi abruptly. A sudden stop may cause the development of a condition called neuroleptic malignant syndrome, which may be a serious risk to your health.
Symptoms include:

acne (loss of muscle mobility);
stiff muscles;
fever;
unstable blood pressure;
tachycardia (accelerated heartbeat);
confusion;
depressed level of consciousness (eg coma)
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE SIDE EFFECTS
Like all medicines, Pramipexole can cause side effects, although not everyone gets them.

The evaluation of these side effects is based on the following incidence:

Very common: occurring in more than 1 in 10 patients;
Common: occurring in 1 to 10 patients in 100;
Uncommon: occurring in 1 to 10 in 1,000 patients;
Rare: occurring in 1 to 10 patients in 10,000;
Very rare: occurring in less than 1 in 10,000 patients;
Not known: Frequency can not be estimated from available data.
If you suffer from Parkinson's disease and you are taking Pramipexole SES, you may experience the following side effects:

Very common:

Dyskinesia (eg unnatural, uncontrolled limb movements);
Drowsiness;
Dizziness;
Nausea (lifting);
Hypotension (low blood pressure).
Common:

An urge to behave in an unusual way;
Hallucinations (see, hear or feel things that are not there);
Confusion;
Fatigue (exhaustion);
Insomnia (insomnia);
An excess of fluids, usually in the legs (peripheral edema);
Headache;
Unusual dreams;
Constipation (constipation);
Restlessness;
Amnesia (memory disorders);
Impaired vision;
Vomiting (from nausea);
Weight loss.
Uncommon:

Paranoia (eg excessive fear for his welfare);
Craving;
Excessive drowsiness during the day and suddenly falling asleep;
Hyperkinesia (increased movements and inability to stay calm);
Increase in weight
Increased sexual desire (eg increased libido);
Allergic reactions (eg rash, itching, hypersensitivity);
Seizures;
Pathological gambling, especially at high doses of Pramipexole SESCi;
Over-sexuality;
Intrusive shopping.
Not known:

Increased nutrition (greasy meals, hyperphagia).
If any of these side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor and pharmacist.

5. HOW TO STORE PRAMIPEXOLE
Keep out of the reach and sight of children.
Do not use Pramipexole  after the expiry date which is stated on the carton or blister after EXP. The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Store in the original package in order to protect from light.
Medicines should not be disposed of with household waste water or household waste. Ask your pharmacist how to dispose of medicines you no longer need. These measures will help to protect the environment.
MORE INFORMATION
What Pramipexole contains
The active substance is pramipexole.
Pramipexole 0.18 mg tablets: Each tablet contains 0.18 mg pramipexole.
Pramipexole 0.7 mg tablets: Each tablet contains 0.7 mg pramipexole.

The other ingredients are: mannitol, corn starch, hydroxypropylcellulose, colloidal anhydrous silica, magnesium stearate.

What Pramipexole looks like and what it contains
0.18 mg tablets: white, biconvex, oblong tablets with a dividing line on either side of approximately 8 mm x 4 mm.

0.7 mg tablets: white, round, flat tablets with a dividing line on one side, approximately 9 mm in diameter.

The tablet can be divided into two equal halves.
Pramipexole  is available in ORA / Aluminum / PVC / Aluminum blisters of 10 tablets each, in boxes containing 1, 3 or 10 blisters.
Pack size: 10, 30 or 100 tablets.
Not all types of packaging can be placed on the market.

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