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What is Tanydon HCT and what it is used for
Tanydon HCT is a combination of two active substances in one tablet - telmisartan and hydrochlorothiazide. Both substances help to control high blood pressure.
Telmisartan belongs to a group of medicinal products called angiotensin II receptor antagonists. Angiotensin II is a substance formed in your body that causes blood vessels to contract, thus increasing your blood pressure. Telmisartan blocks the effect of angiotensin II so that the blood vessels are relaxed and the blood pressure decreases.
Hydrochlorothiazide is from the group of medicines called thiazide diuretics that cause an increase in urine output, leading to a decrease in your blood pressure.
If not treated, high blood pressure can damage blood vessels in a number of organs, which can sometimes lead to heart attacks, heart or kidney failure, stroke and blindness. Symptoms as a result of high blood pressure are usually not observed before organ damage occurs. Therefore, it is important to regularly measure blood pressure to check that it is within normal range.
Tanydon HCT is used to treat high blood pressure (essential hypertension) in adults whose blood pressure is not adequately controlled when telmisartan is used alone.
2. What you need to know before you take Tanydon HCT.
Do not take Tanydon HCT:
if you are allergic to telmisartan or any of the other ingredients of this medicine (listed in section 6).
if you are allergic to hydrochlorothiazide or other sulphonamide-derived medicines.
if you are pregnant after the third month (better avoiding the use of Tanidone HCT and early pregnancy - see section "Pregnancy").
if you have severe liver problems such as cholestasis or biliary obstruction (problems with the drainage of bile from the liver and the gall bladder) or any other severe liver disease if you suffer from severe kidney disease.
if your doctor finds you have low potassium levels or high blood calcium levels that do not improve with treatment.
if you have diabetes or have impaired kidney function and are being treated with a medicine to lower blood pressure containing aliskiren.
Tell your doctor or pharmacist before taking Tanidone HCT if any of the above applies to you.
Warnings and precautions.
Talk to your doctor before taking Tanydon HCT if you suffer or have ever suffered from any of the following conditions or illnesses:
Low blood pressure (hypotension) that may occur if you are dehydrated (excessive body water loss) or if you have salt deficiency due to diuretics (detoxifying medicines), a low salt diet, diarrhea, vomiting or hemodialysis.
Kidney disease or kidney transplantation.
Renal artery stenosis (narrowing of the blood vessels of one or both kidneys).
Elevated levels of aldosterone (retention of water and salts in the body accompanied by imbalance of various minerals in the blood).
Systemic lupus erythematosus (also called "lupus" or "SLE"), a disease in which the immune system attacks the body.
The active ingredient, hydrochlorothiazide, may cause an unusual reaction resulting in reduced vision and eye pain. These may be symptoms of increased intraocular pressure and may occur within hours to weeks of onset of administration of Tanidone HCT. This can lead to permanent damage to vision, if not treated,
Talk to your doctor or pharmacist before taking Tanidone HCT:
if you are taking any of the following medicines used to treat high blood pressure:
- ACE inhibitor (eg enalapril, lisinopril, ramipril), especially if you have kidney problems associated with diabetes.
Your doctor may periodically check your kidney function, blood pressure and the amount of electrolytes (eg potassium) in your blood.
See also the information titled "Do not take Tanidone HCT".
- if you are taking digoxin.
You should tell your doctor if you think you are pregnant (or you may become pregnant), Thandidone HCT is not recommended in early pregnancy and should not be taken after the third month of pregnancy as it may cause serious harm to your child if used during this period (see section "Pregnancy").
Treatment with hydrochlorothiazide can cause an electrolyte imbalance in your body. Typical symptoms of water-electrolyte imbalance include dry mouth, weakness, lethargy, drowsiness, restlessness, muscle aches or cramps, nausea, vomiting, muscle fatigue and palpitations (more than 100 beats per minute). You should tell your doctor if you experience any of these symptoms.
medicines such as quinidine, disopyramide, amiodarone, salatol), medicines used in psychiatric disorders (eg thioridazine, chlorpromazine, levomepromazine), or other medicines used to treat heart rhythm ) and other medicines such as some antibiotics (for example sparfloxacin, pentamidine) or some medicines to treat allergic reactions (such as terfenadine).
Medicines for the treatment of diabetes (insulins or oral agents such as metformin)
Cholestyramine and colestipol, medicines for lowering lipid levels in the blood.
Blood pressure boosting medicines, such as noradrenaline.
Muscle relaxants like tubocurarine.
Calcium supplements and / or supplements containing vitamin D.
Anticholinergic medicines (medicines used to treat various diseases such as gastrointestinal spasms, bladder spasm, asthma, travel sickness, muscle spasms, Parkinson's disease and as an anesthetic) such as atropine and biperiden.
Amantadine (a medicine used to treat Parkinson's disease, as well as for the treatment or prevention of certain diseases caused by viruses), other medicines used to treat high blood pressure, corticosteroids, analgesics such as non-steroidal anti-inflammatory drugs NSAIDs), medicines for the treatment of cancer, gout or arthritis.
if you are taking an ACE inhibitor or aliskiren (see also the information titled "Do not take Thannidone HCT" and "Warnings and Precautions").
Tanydon HCT may increase the blood pressure lowering effect of other medicines used to treat high blood pressure or medicines with a blood pressure lowering potential (eg baclofen, amyphosine).
In addition, the blood pressure lowering effect may be enhanced by the use of alcohol, barbiturates, narcotics or antidepressants. You may feel this as dizziness when standing up. Ask your doctor if it is necessary to adjust the dose of another medicine while taking Tanydon HCT.
The effect of Tanydon HCT may be reduced when given with NSAIDs (non-steroidal anti-inflammatory drugs such as aspirin or ibuprofen).
Tanydon HCT with food and alcohol.
You can take Tanidone HCT with or without food.
Do not take alcohol until you talk to your doctor. Alcohol may lower blood pressure and / or increase the risk of dizziness or feeling weak.
Pregnancy and breastfeeding.
You should tell your doctor if you think you are pregnant (or you may become pregnant). Your doctor will usually advise you to stop taking Tanidon HCT before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Tanidon HCT. Thanidone HCT is not recommended during pregnancy and should not be taken if you are pregnant after the third month as it can cause serious harm to your child if used after the third month of pregnancy.
Tell your doctor if you are breast-feeding or intend to breast-feed. Thanidone HCT is not recommended for use by mothers who are breast-feeding and your doctor may prescribe another treatment if you want to breast-feed,
Driving and using machines.
Some people feel dizzy or tired when they take Tanidon HCT. If you feel dizzy or tired, do not drive or operate machinery.
3. How to take Tanydon HCT.
Always take Tanidone HCT exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
The recommended dose of Tanydon HCT is one tablet a day. Try taking a tablet at the same time each day.
You can take Tanydon HCT with or without food. The tablets should be swallowed with some water or other non-alcoholic beverages. It is important to take Tanidone HCT every day until your doctor advises you otherwise.
If your liver is not working properly, the usual dose should not exceed 40 mg / 12.5 mg once a day. The dose is not available with this medicinal product.
If you take more than the required dose of Tanydon HCT.
If you accidentally take too many tablets, you may experience symptoms such as low blood pressure and fast heartbeat. Cases of slow heart rhythm, dizziness, vomiting, decreased kidney function including kidney failure have been reported. Because of the hydrochlorothiazide component, a marked decrease in blood pressure and a low level of potassium in the blood may result in nausea, somnolence and muscle cramps and / or irregular heart rhythm associated with concomitant use of drugs such as digital or some antiarrhythmic agents.
Contact your doctor, pharmacist or nearest emergency center immediately.
If you forget to take Tanydon HCT.
If you forget to take a dose, do not worry. Take the dose as soon as you remember, and then continue taking it as you like
Rare side effects (may affect up to 1 in 1,000 people):
Inflammation of the lungs (bronchitis), activation or worsening of systemic lupus erythematosus (a disease in which the immune system attacks the body causing joint pain, skin rash and fever), sore throat, inflamed sinus, feeling sad (depression ), insomnia (insomnia), visual disturbances, difficulty in breathing, abdominal pain, constipation, abdominal distension (dyspepsia), nausea (vomiting), stomach inflammation (gastritis), hepatic dysfunction (in patients of Japanese origin, big (erythema), allergic reactions such as itching or rash, increased sweating, hives (urticaria), joint pain (arthralgia) and pain in the extremities, muscle cramps, flu-like illness, pain , low sodium, elevated creatinine, hepatic enzymes or blood creatine phosphokinase.
Adverse reactions reported for each individual component may be potential adverse reactions for Tanydon HCT, even if they have not been observed in clinical trials of this product.
The following additional side effects have been reported in patients taking telmisartan alone:
Uncommon side effects (may affect up to 1 in 100 people):
Upper respiratory tract infection (eg sore throat, sore sinus, cold), urinary tract infections, decreased red blood cell count (anemia), elevated potassium levels, slow heartbeat (bradycardia), renal impairment including acute renal failure, weakness, cough.
Rare side effects (may affect up to 1 in 1,000 people):
Decreased platelet count (thrombocytopenia), increased number of certain white blood cells (eosinophilia), severe allergic reactions (eg hypersensitivity, anaphylactic reaction, drug rash), decreased blood sugar (in diabetic patients), upset stomach, eczema skin disorders), arthrosis, tendon inflammation, decreased hemoglobin (blood protein), somnolence.
Very rare side effects (may affect up to 1 in 10,000 people): Progressive pulmonary fibrosis (interstitial lung disease) **
* The event may be accidental or associated with a previously unknown mechanism.
** Cases of progressive pulmonary adhesion have been reported during telmisartan administration. However, it is not known whether the cause is telmisartan.
The following additional side effects have been reported in patients receiving hydrochlorothiazide alone:
Common side effects (may affect up to 1 in 10 people):
Nausea, low levels of magnesium in the blood.
Rare side effects (may affect up to 1 in 1,000 people)
Reduced blood platelet counts, which increases the risk of bleeding or bruising (small purple-red spots on the skin or other tissues caused by bleeding), high blood calcium, headaches.
Very rare side effects (may affect up to 1 in 10,000 people):
Increased pH (impaired alkaline-acid balance) due to low levels of chlorides in the blood.
Adverse reactions of unknown frequency (frequency can not be estimated from the available data):
Inflammation of the salivary glands, decreased number (or even lack) of blood cells, including reduced number of red and white blood cells; severe allergic reactions (eg hypersensitivity, anaphylactic reaction), decreased or loss of appetite; anxiety, fainting, blurred vision or vision in yellow, reduced vision and eye pain (possible signs of acute myopia or acute narrow-angle glaucoma), inflammation of the blood vessels (necrotizing vasculitis), inflammation of the pancreas, stomach upset, yellowing of the skin or eyes (jaundice), lupus-like syndrome (a disease-like condition called systemic lupus erythematosus where the immune system's own immune system attacks the body); increased skin sensitivity to sunlight, rash, redness of the skin, blistering of the lips, eyes or mouth, skin peeling, fever (possible signs of erythema multiforme), weakness, renal inflammation or impaired kidney function, presence of glucose in the urine (glucosuria), fever, impaired electrolyte balance, elevated blood cholesterol levels, decreased blood volume, increased blood glucose levels, difficulty controlling blood pressure glucose levels in patients diagnosed with diabetes mellitus or elevated levels of lipids in the blood.
How to Store Tanydon HCT
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the carton, blister or bottle label after EXP. The expiry date refers to the last day of that month.
[For blister packs from AI / AI:]
This medicine does not require any special storage conditions.
[For AI / PVC / PVDC blisters:]
Do not store above 30 ° C.
Do not dispose of medicines in the sewers or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Package Contents and Additional Information.
What Tanydon contains
The active substances are telmisartan and hydrochlorothiazide
(hydrochlorothiazide). Each tablet contains 80 mg telmisartan and 12.5 mg hydrochlorothiazide
The active substances are telmisartan and hydrochlorothiazide
(hydrochlorothiazide). Each tablet contains 80 mg telmisartan and 25 mg
other ingredients are magnesium stearate (E470b), potassium hydroxide, meglumine, povidone, sodium starch glycolate (type A), microcrystalline cellulose, mannitol (E421).
What Tanydon HCT looks like and contents of the pack.
Tanydon HCT 80 mg / 12.5 mg tablets are white or off-white, 9.0 x 17.0 mm in size, capsule-shaped and "TH 12.5" on both sides.
Tanydon HCT 80 mg / 25 mg tablets are white or off-white, 9.0 x 17.0 mm, oval and biconvex, with the letters "TH" on one side and "25" on the other side.
Package types Cysteria: 28, 30 and 90 tablets.
Not all types of packaging can be placed on the market.
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