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OLMESTA PLUS 20 mg. / 12.5 mg. 30 tablets

Brand: TEVA
Product Code: OLMESTA PLUS 20 mg. / 12.5 mg. 30 tablets
Availability: In Stock
Product viewed: 2591

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What is Olmesta plus 20 mg / 12,5 mg tablets is and what it is used
Olmesta plus 20 mg / 12,5 mg tablet contains two active ingredients olmesartan medoxomil and hydrochlorothiazide, used to treat high blood pressure (hypertension).
Olmesartan medoxomil belongs to a group of medicines called angiotensin II. It lowers blood pressure by dilating blood vessels;
Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics ( "water pills"). It lowers blood pressure by helping the body to separate the excess fluid by stimulating the kidneys to excrete more urine.
Will prescribe Olmesta plus 20 mg / 12,5 mg tablets if self-treatment with olmesartan medokodmil not adequately controlled blood pressure. When administered together, the two active substances in this medicine help lower blood pressure to a greater extent than if taken alone.
You may already be taking medicines to treat your high blood pressure, but your doctor may consider that Olmesta plus 20 mg / 12,5 mg film-coated tablets will decrease to a greater extent.
High blood pressure can be controlled with drugs like Olmesta plus tablets. Your doctor may recommend you to make some changes in your lifestyle in order to help decrease blood pressure (eg to lose weight, stop smoking, reduce intakes of alcohol and salt in the diet). In addition, your doctor may insist on more physically active with regular exercise such as walking or swimming. It is important to follow this advice of your doctor.

2. What you need to know before taking Olmesta plus 20 mg / 12,5 mg tablets
Do not take Olmesta plus 20 mg / 12,5 mg film-coated tablets:
If you think any of the following apply to you or you are unsure, do not take the tablets. Talk to your doctor and follow the advice given to you. Do not take this medication, especially if:
you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6);
you are allergic to substances similar to hydrochlorothiazide (sulfonamides);
if you are pregnant after the third month. (It is better not to take Olmesta plus 20 mg / 12,5 mg tablets during early pregnancy - see point Pregnancy);
have severe kidney disease;
You have a low level of calcium, sodium, high calcium or uric acid in the blood (which can be a cause of occurrence of gout), which do not respond to treatment;
have severe liver disease or yellowing of skin and whites of the eyes (jaundice);
have problems with the drainage of bile from the biliary tract and gallbladder (biliary obstruction, for example. gallstones).
Warnings and Precautions
Before you take the tablets, tell your doctor if any of the following apply to you. Your doctor may insist on more frequent examinations and tests if you have any of the following:
Mild to moderate renal impairment or a kidney transplant;
Liver disease;
Heart failure or problems with the heart valves or heart muscle;
Vomiting or diarrhea that are severe or last for a few days;
Treatment with high doses of water pills (diuretics);
If you're on a diet low in salt;
Disorders of the adrenal glands (eg. Primary aldosteronism);
diabetes;
Lupus erythematosus (autoimmune disease);
Allergy or asthma.
Olmesta plus 20 mg / 12,5 mg tablets may be the reason for increasing fat levels and uric acid in the blood (leads to gout - a painful swelling of the joints). Your doctor may do blood tests at regular intervals to monitor these indicators.
This medicine can alter the levels of certain substances in your blood, known as electrolytes. Your doctor may want to control them at regular intervals. Signs of changes in electrolytes are: thirst, dry mouth, muscle pain or cramps, muscle fatigue, low blood pressure (hypotension), feelings of weakness, laziness, fatigue, drowsiness or restlessness, nausea, vomiting, rarely urination fast heartbeat. If you notice these symptoms, talk to your doctor.

As with other drugs that lower blood pressure, sudden drop in blood pressure in patients with disorders of blood circulation to the heart or brain can lead to heart attack or stroke. Therefore, your doctor will carefully monitor your blood pressure.
Research results
If you are going to study the function of the parathyroid glands, you should stop taking olmesartan medoxomil / hydrochlorothiazide before this study. Before you stop the treatment, ask your doctor for advice.
If you are an athlete, this medicine can affect the results of research on doping and to positivation.
You should tell your doctor if you are (or might become) pregnant.
Olmesta plus 20 mg / 12,5 mg tablets is not recommended for use during early pregnancy and must not be taken if you are pregnant after the third month, as it may seriously harm your baby if you use it in this period (see section pregnancy).

Children and adolescents
Olmesta plus 20 mg / 12,5 mg tablets is not recommended for use in children and adolescents under 18 years of age.

Patients of African descent
As with other similar drugs the blood pressure lowering effect of Olmesta plus 20 mg / 12,5 mg tablets is somewhat smaller in patients of African descent.

Other medicines and Olmesta plus 20 mg / 12,5 mg tablets
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines.
It is particularly important to tell your doctor or pharmacist about any of the following:
Drugs that may increase potassium levels in the blood if used at the same time Olmesta plus 20 mg / 12,5 mg tablets. Yeah, they're like that:
potassium supplements (such as salt substitutes containing potassium);
water pills (diuretics);
heparin (blood thinning);
laxatives;
steroids;
adrenocorticotropic hormone (ACTH);
carbenoxolone (a medicine used for the treatment of ulcers of the mouth and stomach);
penicillin G sodium (aka benzylpenicillin sodium, an antibiotic);
some painkillers such as aspirin or salicylates;
Lithium (a drug used to treat mood swings and some types of depression). When used at the same time with Olmesta plus 20 mg / 12,5 mg film-coated tablets, may potentiate the toxicity of lithium. If you have to take lithium, your doctor will monitor the levels of lithium in blood;
Non-steroidal anti-inflammatory drugs (NSAIDs) (medicines for pain relief, swelling and other symptoms of inflammation, including arthritis). When used together with Olmesta plus 20 mg / 12,5 mg tablets may increase the risk of kidney failure. Additionally, you may weaken the effect of Olmesta plus 20 mg / 12,5 mg film-coated tablets;
Other medicines to lower blood pressure (antihypertensives). The effect of Olmesta plus 20 mg / l2,5 mg film-coated tablets may be increased;
Hypnotics, sedatives and antidepressants. The use of these medications together is Olmesta plus 20 mg / 12,5 mg tablets can lead to sudden sharp drop in pressure when standing;
Some drugs such as baclofen and tubocurarine (used to relax the muscles);
Amifostine and some drugs such as cyclophosphamide or methotrexate (used for cancer);
Cholestyramine and colestipol (to lower fat levels in the blood);
Anticholinergic drugs such as atropine and biperiden;
Drugs such as thioridazine, chlorpromazine, levomepromazine, trifluoperazine, sulpiride, amisulpride, pimozide, sultopride, tiapride, droperidol or haloperidol (for the treatment of mental disorders);
Some drugs such as quinidine, hydroquinidine, disopyramide, amiodarone, sotalol or digitalis (used to treat heart problems);
Drugs such as mizolastan, pentamidine, terfenadine, dofetilide, ibutilide or erythromycin injections which may change heart rhythm;
Oral antidiabetic drugs such as metformin or insulin (lowering of blood sugar levels);
Beta-blockers and diazoxide (used to treat low blood sugar and high blood pressure). Olmesta plus 20 mg / 12,5 mg tablets could change the way they work;
Drugs such as noradrenaline (used for high blood pressure and slow heartbeat);
Drugs such as probenecid, sulfinpyrazone and allopurinol (for gout);
Calcium supplements;
Amantadine (antiviral drug);
Cyclosporine (to prevent rejection after organ transplantation);
Some antibiotics called tetracyclines;
Amphotericin (for the treatment of fungal infection);
Some antacids such as aluminum magnesium hydroxide (to treat excess stomach acidity). The effect of Olmesta plus 20 mg / 12,5 mg tablets may be slightly reduced.
Olmesta plus 20 mg / 12,5 mg film-coated tablets with food, drinks and alcohol
Olmesta plus 20 mg / 12,5 mg tablets may be taken with or without food.
Be careful when you drink alcohol while on treatment with Olmesta plus 20 mg / 12,5 mg tablets because some people feel tired or dizzy. If you happen not take more alcohol, including wine, beer or alcohol-containing beverages.

Pregnancy, lactation and fertility
pregnancy
You should inform your doctor if you are (or might become) pregnant. Your doctor will normally advise you to stop taking Olmesta plus 20 mg / 12,5 mg tablets before you become pregnant or as soon as you find that you are pregnant and will advise you to take another medicine instead Olmesta plus 20 mg of / 12,5 mg tablets. The use of Olmesta plus 20 mg / 12,5 mg tablets is not recommended in early pregnancy and must not be taken if you are pregnant after the third month, as it may seriously harm your baby.

breastfeeding
Tell your doctor if you are breastfeeding or planning to breastfeed. Olmesta plus 20 mg / 12,5 mg film-coated tablets are not recommended for use by mothers who are breastfeeding, and your doctor may choose another treatment for you if you wish to breastfeed, especially if your baby is newborn, or was born prematurely.
Ask your doctor or pharmacist before taking any medicine.

Driving and using machines
However, sometimes during treatment can occur dizziness or drowsiness. If you get any side effects, do not drive or operate machinery until the symptoms disappear. Consult your doctor.
Olmesta plus 20 mg / 12,5 mg tablets contain lactose (a sugar)
If your doctor has told you that you have an intolerance to some sugars, talk to him before you start taking this medicine.

3. How to take Olmesta plus 20 mg / 12,5 mg tablets
Always take this medicine exactly as your doctor has told you. If you are not sure, talk to your doctor or pharmacist.
The recommended dose is one tablet Olmesta plus 20 mg / 12,5 mg daily. However, if your blood pressure is not adequately controlled with this dose, your doctor may change it to a tablet Olmesta plus a 20 mg / 25 mg daily.
Swallow the tablet with water.
Take the dose at the same time each day, such as at breakfast.
Take Olmesta plus 20 mg / 12,5 mg tablets until your doctor tells you to stop taking.
If you take a larger dose Olmesta plus 20 mg / 12,5 mg tablets than necessary
If you take more than your prescribed tablets or child accidentally swallows some tablets, contact your doctor immediately or go to the nearest emergency room. Please bring your own container of your medicine.

If you forget to take Olmesta plus 20 mg / 12,5 mg tablets
If you miss a dose, take it as soon as possible. Do not take a double dose to make up the missed dose.

Acre you stop taking Olmesta plus 20 mg / 12,5 mg tablets
It is important to continue taking Olmesta plus 20 mg / 12,5 mg tablets unless your doctor has recommended to stop taking.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them
If you receive the following stop taking Olmesta plus 20 mg / 12,5 mg tablets and call your doctor immediately:
Swelling of the face, mouth and / or larynx (vocal cords) together with itching and rash may occur very rarely;
Severe dizziness or fainting. If you get these symptoms bed. It is possible that your blood pressure has fallen too much. Some people experience such effects of this group of drugs.
Tell your doctor if you notice:
thirst, dry mouth, muscle pain or cramps, muscle fatigue, low blood pressure (hypotension), feelings of weakness, laziness, fatigue, drowsiness or restlessness, nausea, less frequent urination, rapid heart beat. This may indicate a change in the electrolyte.
Usually in appearance these side effects are mild and do not require discontinuation of treatment.
Common (affects 1 to 10 users in 100):
dizziness (more common in people over 75 years);
headache;
tiredness.
Uncommon (affects 1 to 10 users in 1000):
palpitations.
Not known:
cough, abdominal pain, nausea, vomiting, diarrhea, allergic reactions, lumps under the skin, muscle spasms and muscle pain, acute kidney failure, weakness, lack of energy, feeling unwell.
Some changes in blood tests:
Your doctor will know about the results of blood tests and will tell you if you need to do something extra. Increasing levels of fat in the blood uric acid, blood urea nitrogen, increase or decrease potassium, increased calcium in the blood, a slight increase in serum creatinine and urea, a slight decrease in hemoglobin and hematocrit.
Changes in renal function tests.

Additional adverse reactions reported in the independent use of olmesartan medoxomil and hydrochlorothiazide:

olmesartan medoxomil
Common (affects 1 to 10 users in 100):
Bronchitis, sore throat, stuffy or runny nose, stomach pain, indigestion, gastroenteritis, pain in the chest, back, bones or joints, blood in urine, urinary tract infection, asthenia, flu-like symptoms and swelling of the ankles, feet, legs hands or arms.
Uncommon (affects 1 to 10 users in 1000):
Spinning sensation (vertigo, pain or chest discomfort (angina known as angina pectoris).
Not known:
Itching, skin rash, facial swelling, impaired renal function, renal failure, lack of energy.
Some changes in blood tests:
Elevated levels of certain substances that define muscle and kidney function as creatine or creatine phosphokinase (CPK), reduced numbers of certain blood cells known as platelets (thrombocytopenia).
hydrochlorothiazide:
Common (affects 1 to 10 users in 100):
Dizziness, confusional state, dizziness, stomach pain, indigestion, feeling bloated, nausea, vomiting, diarrhea, constipation, headache and fatigue.
Uncommon (affects 1 to 10 users in 1000):
Reduced or absent appetite, sensitivity to light.
Rare (affects 1 to 10 users in 10,000):
Swelling and inflammation of the salivary glands;
Reduced leukocyte reduced platelets, anemia, bone marrow damage;
Anxiety, feeling depressed, depression, trouble sleeping, apathy, tingling and numbness, seizures;
Appearance of yellow, blurred vision, dry eyes;
Irregular heart beat, inflammation of the blood vessels clots in blood vessels (thrombosis or embolism), difficulty breathing;
Inflammation of the pancreas, yellowing of skin and whites of the eyes (jaundice), inflammation of the gallbladder;
Symptoms of lupus erythematosus such as rash, joint pains and cold hands and fingers, anaphylactic reactions (hypersensitivity reactions);
Blistering and peeling of the skin, muscle cramps and weakness (sometimes leading to inability to move);
Impaired renal function, renal failure, difficulty in achieving an erection in men fever.
Very rare (affects less than 1 user in 10 000):
Blockade of the bowel (paralytic ileus).
Some changes in blood tests:
Elevated levels of fat, elevated blood sugar levels, increased uric acid levels, electrolyte imbalances (changes in the level of sodium, magnesium and chloride in the blood). Increased levels of sugar in the urine were also observed.
If you notice any side effects, talk to your doctor or pharmacist. This includes any side effects not listed in this leaflet.

5. How to store Olmesta plus 20 mg / 12,5 mg tablets
Do not store above 25 ° C.
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the blister and carton after "EXP". The expiry date refers to the last day of that month.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information
What Olmesta plus 20 mg / 12,5 mg tablets
The active substances are olmesartan medoxomil and hydrochlorothiazide.
Each tablet contains 20 mg of olmesartan medoxomil and hydrochlorothiazide 12,5 mg.

Other ingredients are:
Core:
Lactose monohydrate, microcrystalline cellulose, povidone (K-30), croscarmellose sodium, magnesium stearate, macrogol.
Film Coating:
Hypromellose, macrogol, titanium dioxide (E171), iron oxide red (E172), iron oxide yellow (E172).

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