Zerit 30 mg
Zerit 30 mg
Current active substance is 30 mg stavudine
The other ingredients are lactose, magnesium stearate, microcrystalline cellulose and sodium starch glycolate.
the capsule is composed of gelatin, iron oxide, silicon dioxide, sodium lauryl sulfate, titanium dioxide. The inscription on the capsule using edible ink.
What is Zerit and what is it used?
How come and look how hard capsules Zerit?
Zerit 30 mg hard capsules are light and dark orange, like on imprinted with BMS 1966 "on the other" 30 ". Capsules come in blister packs of 56 hard capsules.
What is it and how does Zerit!
Zerit belongs to a group of antiviral drugs, known as antiretrovirals, called nucleoside reverse transcriptase inhibitors. They are used to treat patients infected with the Human Immunodeficiency Virus / HIV /
This drug, in combination with other antiretroviral agents, decreasing the amount of the virus, although levels remain at a low level. The drug also increases CD4 cell counts. These CD4 cells play an important role in maintaining a healthy immune system, "fight" infection. Response to treatment with Zerit varies between patients. Therefore, your doctor will monitor the effectiveness of your treatment.
Zerit may improve your condition, but it does not cure your infection by human immunodeficiency virus. Treatment with Zerit does not reduce the risk of transmitting the virus to others through sexual contact or blood contamination. Therefore, you must continue to take appropriate measures to prevent transmission of the virus to others.
What you should know before you start taking Zerit?
Do not take Zerit if:
Have hypersensitivity to stavudine or any of the other ingredients of the medicine.
Take special care when taking Zerit in the following circumstances:
Before taking this medicine tell your doctor if:
- Have kidney or liver disease
- If you have peripheral NEUROPATHY
- You had pancreatitis
Patients with chronic hepatitis B or C and treated with antiretroviral agents are at increased risk of severe liver damage, sometimes fatal, so may require blood tests for control of liver function.
The class of medicines to which it belongs and Zerit can sometimes lead to a fatal condition called lactic acidosis, together with an enlarged liver. This condition usually does not occur until a few months of treatment. This rare but very serious side effect occurs more often in women, particularly those with overweight. In addition, there are rare cases of liver failure / renal failure or fatal hepatitis.
Always contact your doctor at the onset of:
- Persistent numbness, tingling or pain in the feet and / or hands, muscle weakness, or
- Abdominal pain, nausea, or vomiting or
- Rapid deep breathing, drowsiness
Patients on antiretroviral therapy may develop Redistribution, accumulation or loss of body fat. Contact your doctor if you notice changes in body fat.
Inform your doctor if you are pregnant or planning a pregnancy. Since there is evidence for the occurrence of lactic acidosis in pregnant women who received stavudine in combination with other antiretroviral agents during pregnancy this medication should be taken only after consulting a doctor.
Inform your doctor if you are breast-feeding. Recommended that women infected with HIV never to breastfeed in order to avoid transmission of HIV in the infant.
Important information about some of the ingredients of Zerit
These capsules contain lactose. You should not take this medicine if you suffer from a rare hereditary problems of galactose intolerance, lactase deficiency or glucose-galactose malabsorption.
How to take Zerit?
Dosage and instructions for proper use?
Your doctor will determine your dose based on your weight and individual characteristics. Please follow these recommendations closely as they will give you the best chance to delay the development of resistance to this drug. Do not change dose and continue taking it unless your doctor tells you otherwise.
Adults and children weighing 30 kg or more, the usual starting dose is 30 to 40 mg twice daily. For children over the age 3mesechna weighing less than 30 kg, the dosage is 1 mg / kg twice daily.
For optimal absorption, the capsules should be swallowed with a glass of water, preferably one hour before a meal and on an empty stomach. If this is not possible, Zerit may be administered with a light meal. In case of difficulty swallowing the capsules, you can open them carefully and mix the contents with some food.
Possible side effects
The most common side effects in adults taking Zerit in combination with other anti-HIV infection were skin rash, headache, dizziness and peripheral NEUROPATHY. Serious but uncommon side effects are pancreatitis, hepatic dysfunction and lactic acidosis.
There have been other side effects such as fatigue, nausea, diarrhea, indigestion, abdominal pain, abnormal fat distribution, breast enlargement in men, numbness or weakness in the arms and legs, MUSCLE PAIN.
During studies of adults in some patients taking Zerit in combination with other anti-HIV infection observed changes in mood or ability to think clearly. These symptoms include anxiety, sleep problems, depression, difficulty in thinking and sleeping.
Combination antiretroviral therapy may also cause an increase in lactic acid and sugar in the blood, hyperlipemia, and insulin resistance.