ZULBEKS. 20 mg. 28 tablets
ZULBEKS. 20 mg. 28 tablets
ZULBEKS WHAT IS AND WHAT IT IS USED FOR ?
Zulbeks tablets contain rabeprazole . It belongs to a class of drugs called proton pump inhibitors . They act by reducing the amount of acid produced in the stomach .
Zulbeks tablets are used for :
• active duodenal ulcer or active benign gastric / stomach ulcer ( peptic ulcer) .
Erosive or ulcerative symptomatic gastro- esophageal reflux disease (GERD ), which is commonly called the esophageal irritation caused by the acid associated with an increase of the acid in the stomach, or for long term treatment of GERD ( maintenance treatment of GERD) .
Symptomatic treatment of moderate to very severe gastro- oesophageal refluksivna disease (symptomatic GERD) , also associated with an increase heartburn .
Syndrome Zollinger-Ellison, a rare disease in patients whose stomachs produce very large amounts of acid.
In combination with two antibiotics (clarithromycin and amoxicillin ) Zulbeks tablets are used for the eradication of H Pylori infection in patients with peptic ulcer disease
2 . BEFORE YOU TAKE ZULBEKS
Do not take Zulbeks :
- If you are allergic (hypersensitive) to rabeprazole or any of the other ingredients of Zulbeks
- If you are pregnant, think you may be pregnant, or are breast-feeding ( see 'Pregnancy and lactation ')
Take special care with Zulbeks
Tell your doctor or pharmacist :
- If you are allergic to other proton pump inhibitors
- If you have gastric cancer
- If you have a history of liver disease
- If you are taking atazanavir ( a medicine used to treat HIV)
- If you are taking this medicine for a long time , your doctor will want to monitor you .
Some patients have reported blood problems and liver problems , which resolved after discontinuation of rabeprazole .
Taking proton pump inhibitors as Zulbeks , especially for a period longer than one year may slightly increase the risk of fractures of the hip , wrist or spine to you. Tell your doctor if you have osteoporosis or are taking corticosteroids (they may increase the risk of osteoporosis) .
Zulbeks should not be used in children.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Tell your doctor or pharmacist :
- If you are taking ketoconazole or igrakonazol (medicines used to treat fungal infections)
- If you are taking atazanavir (a medicine used to treat HTV)
Pregnancy and lactation
Consult your doctor or pharmacist before taking any medicine. Do not take Zulbeks tablets if you are pregnant or think you may be pregnant . Do not take Zulbeks tablets if you are breastfeeding or plan to breastfeed .
Driving and using machines
You may feel drowsy while taking Zulbeks . If it happens that drive or operate any tools or machines.
2 . HOW TO TAKE ZULBEKS ?
Always take Zulbeks exactly as your doctor tells you . If you are not sure, ask your doctor or pharmacist.
You should swallow whole tablets ZULBEKS . DO NOT crush, or chew !
The dosages below are those which are generally recommended for adults and the elderly . Do not change the dose or duration of treatment itself . Zulbeks should not be used in children.
Active duodenal ulcer and active benign gastric ulcer : The usual dose is one tablet Zulbeks 20 mg once daily. If you have an active duodenal ulcer , the treatment is expected to last for four weeks, but after that period, your doctor may decide to continue your treatment for another four weeks.
If you have an active benign gastric ulcer , the treatment is expected to last six weeks , but after this period, your doctor may decide to continue your treatment for another six weeks.
Erosive or ulcerative gastro -oesophageal reflux disease : The usual dose is one tablet Zulbeks 20 mg once daily. Your treatment is expected to last for four weeks, but after that period, your doctor may decide to continue your treatment for another four weeks.
Maintenance treatment of GERD
The usual dose is one tablet Zulbeks 10 mg or 20 mg once daily . Your doctor will advise you on how long to take tablets. You should regularly check and proofread your doctor to assess the effect of the tablets and your symptoms .
The usual dose is one tablet Zulbeks 10 mg once daily . Your treatment once daily is expected to last up to four weeks. If symptoms do not disappear within four weeks, consult your doctor. After these initial four weeks of treatment if your symptoms recur, your doctor may tell you to take one tablet Zulbeks 10 mg, and only be taken when necessary to control symptoms.
The usual recommended dose is three tablets Zulbeks 20 mg once a day in the beginning. The dose may be adjusted by your doctor depending on how you respond to treatment. Your doctor will tell you how many tablets to take and when to take them. You should see your doctor at regular intervals for review to assess the effect of your tablet and your symptoms .
Eradication of H. pylori
The usual recommended dose is 20 mg Zulbeks which must be taken (in combination two antibiotics - clarithromycin, amoxicillin and 500 mg of 1 g) twice daily usually for 7 days. Relief of symptoms will usually occur before the ulcer has healed completely. Therefore, it is important not to stop taking the tablets unless your doctor tells you . For more information about the other drugs for the eradication of H. pylori see their leaflets with information about products.
If you take more tablets Zulbeks than you should
Do not take more tablets than prescribed . If you take more tablets than prescribed dose , please consult your doctor or hospital immediately. Always take the tablets and the container with you to the hospital so that the doctor knows what has been accepted !
If you forget to take Zulbeks
If you forget to take a dose , just take it as soon as you remember and then continue as usual. If you forget to take your medicine for more than five days , call your doctor before taking a larger dose of the drug .
Do not take a double dose to make up for a missed dose. If you stop taking Zulbeks
Do not change your dose or stop treatment without discussing it with your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 . POSSIBLE SIDE EFFECTS
Like all medicines, Zulbeks can cause side effects, although not everybody gets them .
Very common: They occur in 1 out of every 10 users
Common: may affect 1 to 10 users in 100
Nechesgi : can occur in 1 to 10 of 1000 users
Rare: may occur in 1 to 10 per 10 000 users
Very rare: can occur in less than 1 in 10,000 users
Not known: frequency can not be predicted from the available data .
Stop taking Zulbeks and see a doctor immediately if you notice redness of the skin with blisters or peeling. May occur and large blisters and bleeding in the lips , eyes, mouth , nose and genitals. This may be syndrome "Stevens-Johnson" or toxic epidermal necrolysis .
Other possible side effects:
- Insomnia ( difficulty sleeping ) Headache , dizziness
- Cough, pharyngitis (sore throat), rhinitis ( runny nose )
- Diarrhea , vomiting, nausea, abdominal pain , constipation, flatulence (gas )
- Pain without a cause , back pain
- Asthenia ( weakness) , flu-like syndrome
- Nervousness or drowsiness Bronchitis , sinusitis
- Dyspepsia ( indigestion ) , dry mouth , belching
- Skin rash , redness of the skin
- Muscle or joint pain, leg cramps, fractures of the hip , wrist or spine
- Urinary tract infection Chest Pain
- Chills , fever
- Changes in the values in liver function tests
- Anorexia (loss of appetite) Depression
- Hypersensitivity - severe and sudden allergic reaction such as swelling of the face , low blood pressure, shortness of breath, which disappears after discontinuation.
- Visual disturbances
- Gastritis ( upset stomach or stomach pain ) , stomatitis ( sore mouth), taste disturbances
- Liver problems such as hepatitis (inflammation of the liver) and jaundice (yellowing of the skin and whites of the eyes) , hepatic encephalopathy (brain dysfunction due to liver disease )
- Itching, sweating, skin blisters ( these effects usually disappear after cessation of treatment)
- Kidney problems , such as interstitial nephritis ( disease of the connective tissue in the kidneys)
- Weight gain changes in white blood cells :
- Neutropenia (decrease of neutrophils, a type of white blood cell ) or leukopenia ( decreased white blood cell count) - the number of white blood cells , leading to frequent infections , such as sore throat or high temperature (fever ) , or mouth ulcers or throat. Leukocytosis ( increase in white blood cells), thrombocytopenia (reduced blood platelets ) - Reduction of blood platelets resulting in bleeding or bruising more easily than usual.
Severe skin reactions are:
Erythema multiforme (skin blistering ) Toxic epidermal necrolysis ( severe skin lesions with involvement of the top layer of skin from the lower layers of the skin on the body ) syndrome Stevens-Johnson ( large blisters, peeling and bleeding under the skin and also in the mouth , eyes, nose and mouth )
- Not known:
- Swelling of the legs or ankles
- Breast swelling in men
- Hyponatremia ( low sodium levels in the blood) - the symptoms are nausea and malaise with muscle weakness or confusion. If you are taking rabeprazole more than three months is possible levels of magnesium in your blood decrease. Low levels of magnesium may occur with nausea , involuntary muscle contractions , disorientation , convulsions, dizziness , increased heart rate . If you experience any of these symptoms , tell your doctor immediately. Low levels of magnesium may also bring about a reduction of the potassium or calcium level in blood. Your doctor may decide to perform regular blood tests to monitor your levels of magnesium.
If any of the side effects gets serious , or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5 . HOW TO STORE ZULBEKS ?
Keep out of the reach of children.
Zulbeks not use after the expiry date stated on the carton and blister. Expiry date refers to the last day of the month .
Store in the original package to protect from moisture and light. Do not store above 30 ° C.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.
6 . FURTHER INFORMATION
What does Zulbeks ?
- The active substance is rabeprazole sodium (rabeprazole sodium). Each gastro -resistant tablet contains 10 mg of rabeprazole sodium equivalent to 9,42 mg rabeprazole . Each gastro -resistant tablet contains 20 mg of rabeprazole sodium equivalent to 18,85 mg rabeprazole
Other Ingredients : In the core of the tablet - mannitol ( B421 ) , magnesium oxide light ( E530 ) hidroksittropil cellulose ( E463 ) , hydroxypropyl cellulose , low - substituted ( E463 ) and magnesium stearate ( E572 ) and in the coating of ethylcellulose - ( E462 ), magnesium oxide , light ( E530 ), hypromellose phthalate, diacetylated monoglycerides ( E472a ) , talc ( E553Y ), titanium dioxide (E171) , red iron oxide ( E172) (only 10 mg) and iron oxide yellow ( E172) (only 20 mg) in the coating.
Zulbeks looks like and contents of the pack ?
Tablets 10 mg are orange- pink, biconvex , round tablet with bevelled edges.
Tablets 20 mg are pale brownish- yellow, biconvex round .
Both concentrations are available in boxes of 7 , 10, 14,15 , 28, 30,56 , 60, 90,98 and 100 gastro-resistant tablets in blisters. Not all pack sizes may be marketed.