ZOVIRAX. 250 mg. 5 ampules

GlaxoSmithKline
ZOVIRAX. 250 mg. 5 ampules
€ 179.00
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Zovirax I.V. is an antiviral medicine. It is used to treat herpes encephalitis, herpes zoster and varicella.
This drug is used to treat infections caused by herpes simplex virus and for the prevention of recurrent attacks of infections caused by herpes simplex virus in people with weakened immune systems. It is applied to prevent cytomegalovirus disease in patients with bone marrow transplantation

ZOVIRAX. 250 mg. 5 ampules

 
 
WHAT ZOVIRAX AND WHAT IT IS USED
 
Zovirax. is an antiviral medicine. It is used to treat herpes encephalitis , herpes zoster and varicella .
 
This drug is used to treat infections caused by herpes simplex virus and for the prevention of recurrent attacks of infections caused by herpes simplex virus in people with weakened immune systems . It is applied to prevent cytomegalovirus disease in patients with bone marrow transplantation.
 
Do not use Zovirax.
• if you are allergic (hypersensitive) to aciclovir or valaciclovir or any of the other ingredients of Zoviraks IV
 
Take special care with Zovirax
Before you are given Zovirax, consult your doctor or pharmacist :
• If you have kidney problems
• if you are elderly .
If you are not sure if any of the above applies to you , talk to your doctor or pharmacist before you are given IV Zoviraks
 
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
 
Tell your doctor or pharmacist if you are taking any of these medicines:
• probenecid
• cimetidine
• tacrolimus , cyclosporine , mycophenolate mofetil
 
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine .
Zovirax. can be used during pregnancy only if the expected benefit to the mother outweighs the potential risk to the fetus .
 
The active ingredient acyclovir passes into breast milk . Therefore , caution is advised when administering IV Zovirax in nursing mothers .
 
Driving and using machines
Zovirax. used primarily in patients who are hospitalized and information on ability to drive and use machines usually not applicable. No studies to investigate the effect of IV Zovirax on ability to drive and use machines.
 
 
3 . HOW TO USE ZOVIRAX.
 
Before administration Zovirax must be dissolved . Apply by slow intravenous infusion over one hour.
 
Sometimes doctors prescribing this drug at doses other than those provided below , depending on the patient's condition and response to treatment . If you think this may apply to you, talk with your doctor .
 
Treatment of varicella
Children between 3 months and 12 years
• The usual dose is 250 mg per square meter body surface every 8 hours for 5 days.
 
Treatment of chickenpox and herpes zoster
Adults and children 12 years and above
• The usual dose is 5 mg per kilogram of body weight every 8 hours for 5 days.
 
Treatment of infections caused by herpes simplex virus
Children under 3 months
• The usual dose is 10 mg per kilogram of body weight every 8 hours for 10 days.
 
Children between 3 months and 12 years
• The usual dose is 250 mg per square meter body surface every 8 hours for 5 days.
 
Adults and children 12 years and above
• The usual dose is 5 mg per kilogram of body weight every 8 hours for
5 days .
 
Treatment of herpes encephalitis
Children under 3 months
• The usual dose is 10 mg per kilogram of body weight every 8 hours for 10 days.
 
Children between 3 months and 12 years
• The usual dose is 500 mg per square meter body surface every 8 hours for 10 days.
 
Adults and children 12 years and above
• The usual dose is 10 mg per kilogram of body weight every 8 hours for 10 days.
 
Inhibition of infections caused by herpes simplex virus
The dose and duration of treatment depends on the duration of the period of risk .
 
Prevention of cytomegalovirus infections in patients with bone marrow
transplantation
• The usual adult dose is 500 mg/m2, intravenously three times a day at 8 hours. In patients with bone marrow transplantation application is recommended to start 5 days before surgery and continued until 30 days after it. It has been found that administration of high-dose IV Zovirax reduces the incidence and delays the development of cytomegalovirus infection . The doctor may prescribe intake Zovirax tablets by mouth after a course of IV Zoviraks There are limited data confirm that for the prevention of cytomegalovirus infection in children aged over 2 years, bone marrow transplantation may be the adult dose .
 
If you think you have been given too much medication dose or if someone else has taken the drug by mistake , contact your doctor .
 
 
4 . POSSIBLE SIDE EFFECTS
 
Like all medicines, Zovirax can cause side effects, although not
everybody gets them.
 
The following adverse reactions have been reported during administration of  Zovirax
 
Common side effects
These may affect up to 1 in 10 people:
• nausea , vomiting
• phlebitis (inflammation of veins )
• itching, hives , rashes (including photosensitivity )
• reversible increases in liver enzymes
• the level of urea and creatinine in the blood.
 
Uncommon side effects
These may affect up to 1 in 100 people:
• anemia (decreased numbers of red blood cells and ( or ) of hemoglobin ) , leukopenia ( reduction in the number of white blood cells) , thrombocytopenia ( decrease in the number of platelets in the blood cells ) .
 
Very rare side effects
These may affect up to 1 in 10,000 patients:
• headache, dizziness, diarrhea and abdominal pain
• difficulty in breathing
• symptoms of a severe allergic reaction - a sudden hard wheezing , tightness of the chest , collapse , swelling of eyelids, face , lips, or elsewhere on the body , skin rash .
Tell your doctor immediately if you experience any of these symptoms . Do not administer medicine unless your doctor decides otherwise.
• agitation, confusion , tremor ( shaking), ataxia (poor coordination ) , dysarthria ( difficulty speaking ) , loss of contact with reality , hallucinations, seizures , drowsiness , coma ( unconsciousness ) . These reactions are usually reversible, has been reported in patients with renal
impairment or the elderly .
• increase in bilirubin , hepatitis ( liver inflammation ) , jaundice (yellowing of the skin and (or ) the whites of the eyes)
• acute renal failure, renal impairment
• pain in the kidneys
• fatigue , fever, local inflammatory reactions .
 
In some cases, Severe local inflammatory reactions leading to breakdown of the skin of accidental Zovirax outside the blood vessels in an acquisition .
 
If any of the side effects gets serious, or you notice other effects not listed in this leaflet , please tell your doctor or pharmacist.
 
 
5 . HOW TO STORE ZOVIRAX
 
• Do not store above 25 ° C.
• Keep out of reach of children.
• Do not use Zovirax after the expiry date stated on the pack . The expiry date refers to the last day of that month.
• Reconstitute immediately before use.
• Any unused solution should be discarded.
 
 
6 . ADDITIONAL INFORMATION
 
What does Zovirax
 
The active ingredient is acyclovir . Each sample bottle contains 250 mg of acyclovir in the form of sodium salt.
 
The other component is sodium hydroxide.
 
Looks like Zovirax. and contents of the pack
 
Zovirax. a powder for solution for infusion .
Zovirax. sold 5 vials per carton .
 
 
€ 179.00
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