ZIBOR Fl. 3500 IU
ZIBOR Fl. 3500 IU
What Zibor 3500 and what it is used?
Zibor 3500 (bemiparin sodium) belongs to a group of medicines called anticoagulants (anticoagulant) that help prevent blood from clotting in the blood sadove.Zibor 3500 is available in packs of 2 and 10 pre-filled syringes with 0,2 ml solution for injection. One syringe of 0,2 ml contains bemiparin sodium 3500 IU anti-Ha.Tova medicine is always prescribed by a physician and is used to prevent blood from clotting, eg. in the veins of the legs and / or lungs, which can occur if you are undergoing surgery. It is also used to prevent blood clots in the tubes of the dialysis apparatus.
What you should consider before using Zibor 3500?
Please read carefully the instructions in section 3 "How to use Zibor 3500?"
You should not use Zibor 3500 in the following cases:
if you have had an allergic reaction to another medicine containing bemiparin, heparin or substances derived from pigs;
If you are suffering from heparin-induced thrombocytopenia - a condition in which the blood is decreased platelets (blood cells important for blood clotting) and in laboratory tests they clump together in the application of Zibor 3500. Your doctor will tell you if you suffer from this disease;
if you suffer from a condition that leads to a tendency to excessive bleeding;
if you have severe liver and / or pancreatic disease;
If you have disseminated intravascular coagulation (DIC systemic intravascular coagulation), which is due to heparin-induced decrease in the platelet count;
if you suffer from a condition called endocarditis (inflammation of the lining of the heart and heart valves). Your doctor will tell you if you have it;
if you have a disease with a high risk of bleeding (eg, active stomach ulcers, stroke, brain tumors, or if you have a brain haemorrhage);
If you have an injury or are scheduled for surgery on the brain, spinal cord, eyes and / or ears.
Particular care with Zibor 3500 is necessary:
if you have liver or kidney disease;
if you have high blood pressure and / or difficult to control it,
if you have a stomach ulcer;
if you suffer from thrombocytopenia - a condition in which the number of platelets in the blood is reduced, leading to easy bruising and bleeding. Your doctor will tell you if you suffer from this disease;
if you have kidney stones and / or urinary tract;
if you suffer from a disease with an increased tendency to bleed. Ask your doctor if you are unsure;
If you have an eye disease caused by blood vessels;
If sedation yet to be implemented in the spine (epidural or spinal anesthesia before surgery) and / or lumbar puncture yet (lumbar puncture spine laboratory tests);
if you have diabetes or if you are aware of the high levels of potassium in the blood;
if your skin suddenly become mottled with bruises and / or red painful spots. If this happens, tell your doctor immediately!
Children: application of Zibor 3500 in children is not recommended.
Elderly: must be used the same dose as for other age groups.
Renal and hepatic impairment: not enough data to be able to recommend bemiparin in these patients.
Pregnancy does not have enough experience to be able to recommend the use of Zibor 3500. Before starting treatment with Zibor 3500, you must tell your doctor if you are pregnant or suspect that you are pregnant. Before administration of any medication, consult your doctor or pharmacist
Lactation before treatment Zibor 3500, you must tell your doctor if you are breastfeeding. Before administration of any medication, consult your doctor or pharmacist
Driving and operating machinery
Bemiparin no effect on the ability to drive or operate dangerous machinery and precision.
Interactions with other drugs
Tell your doctor if you are taking anticoagulant drugs, such as vitamin K antagonists (warfarin), NSAIDS, such as ibuprofen, platelet inhibitors, such as acetylsalicylic acid (aspirin), ticlopidine, clopidogrel, and others; drugs that prevent potassium loss , heart medications, such as nitroglycerin and medications that increase blood volume by dextran.
Medical tests that may be required
Some patients may need to determine the number of blood platelets. Your doctor will decide if it is necessary.
If you suffer from certain medical conditions (diabetes, kidney disease) or if you take medicines to prevent potassium loss, your doctor may check potassium levels in the blood.
How to use Zibor 3500?
Zibor 3500 should not be injected into the muscle and should not be mixed with other inzhektsii.Za prevent blood from clotting in the veins in orthopedic operatsiyaZibor 3500 is generally given by a doctor or nurse by subcutaneous (this means that injected under the skin, usually in a fold of skin on the abdomen or upper thigh). Before or after surgery apply one dose of the product (one syringe). Subsequent days apply one dose (one syringe) every day. Your doctor will tell you how long it would continue treatment.
Prevention of clotting during hemodialysis
When used in hemodialysis Zibor 3500 is usually given by injection of a bolus dose (one syringe) into the arterial end of the dialysis apparatus.
If you apply more than the recommended dose Zibor 3500
This can lead to bleeding. If this happens, tell your doctor immediately or go to the emergency room of the nearest hospital and take this leaflet with you.
If you miss the application Zibor 3500
Do not take a double dose to make up for the missed dose and consult as soon as possible with your doctor. He will advise you how to proceed in this case.
What are possible side effects?
Like all medicines, Zibor 3500 can cause side efekti.Pri application Zibor 3500, may occur at the bruises are treated with inzhektirane.Ako Zibor 3500 (or similar substances) for a long time may occur osteoporosis - a condition in which bones become fragile due to loss of kaltsiy.Kogato apply normal doses, though rare, can occur bleeding. If you notice blood in your urine or feces or other bleeding, tell your doctor immediately or go to the emergency room of the nearest bolnitsa.Chesto observed increase in liver enzymes in the blood (transaminases). In rare cases, may decrease the number of trombotsitite.Ryadko may show mild skin reactions (rash, pruritus). Very rarely serious allergic reactions (fever, shortness of breath, skin rash, flushing, malaise, nausea, vomiting). If this occurs, discontinue use of Zibor 3500 and tell your doctor immediately or go to the emergency room of the nearest bolnitsa.Mnogo often if you applied anticoagulant medications and epidural or spinal anesthesia, the spine can occur bleeding . This can affect nerves and can lead to loss of strength or sensation in the legs or lower body. If this happens, tell your doctor or sestra.Ako notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
How to Store Zibor 3500?
Keep out of reach of children! Do not store above 30 * C! Do not freeze container with a single dose. Unused to destroy! Do not use if the protective packaging is torn or damaged. We use only clear, transparent or slightly yellowish solutions without visible particles. Any unused product should be disposed of in accordance with local requirements.
Do not use after the expiry date printed on the package! Zibor 3500 should be used immediately after first opening