ZEPLAN. 20 mg. 28 tablets
ZEPLAN. 20 mg. 28 tablets
What Zeplan and what it is used ?
Zeplan is a drug that regulates lipids (fats ) . It lowers LDL ( bad) cholesterol and fatty substances in the blood called triglycerides, and raises HDL ( good) cholesterol . Belongs to a class of medicines called hydroxy- methyl -glutaryl coenzyme A (HMG-CoA) reductase inhibitori.Namalyavaneto the high levels of cholesterol may help reduce the possibility to develop coronary heart disease . If you have coronary artery disease and high levels of plasma cholesterol (5.5 mmol / 1 or more) Zeplan in conjunction with a standard cholesterol-lowering diet helps to prolong your life , reduce the risk of heart attack , stroke or transient disorders of cerebral circulation , as well as to reduce the need to carry out a surgical procedure to improve the blood supply to the heart. Zeplan also slows the progression of atherosclerosis and reduces the appearance of new atherosclerotic promeni.Pri some family situations characterized by very high plasma concentrations of cholesterol or triglycerides, or a combination of both, Zeplan combined with diet can help to control the amount of cholesterol , which take with food and the amount of cholesterol which your body is formed.
What medicinal ingredients and excipients containing film-coated tablet Zeplan ?
Zeplan a tablet containing 20 mg of active substance simvastatin.
ZEPLAN 20 mg, yellow colored, round, biconvex film-coated tablets.
Film-coated tablets 20 mg Zeplan contains as inactive ingredients: lactose , butyl hydroxyanisole , ascorbic acid, citric acid monohydrate , microcrystalline cellulose PH 101 , pre-gelatinized starch , magnesium stearate, Opadry 39G22514
When you must not be taken Zeplan ?
Do not take Zeplan if:
- You are allergic to any ingredient ;
- Have established active liver disease;
- Have found unexplained prolonged elevation of liver enzymes in the blood ;
- You have porphyria ;
- Suffer from myopathy ;
- Are pregnant or breastfeeding;
- You are a woman of childbearing age not using non-hormonal birth control methods to prevent pregnancy ;
- Simultaneously taking gemfibrozil .
Zeplan not recommended for use in children .
What you should know before taking Zeplan ?
You must follow a standard cholesterol-lowering diet before the Zeplan and need to continue with during treatment with produkta.Saobshtete doctor about any problems with drugs that have or have had , as well as the presence allergies .
Tell your doctor if you consume large amounts of alcohol or have suffered in the past from liver disease.
Those who use anticoagulants (drugs inhibiting coagulation ) may require dose adjustment of lekarstvoto.Zheni of childbearing age should not take simvastatin if definitely not planning future pregnancies .
If you become pregnant while taking Zeplan stop the drug immediately and contact your doctor .
Women taking Zeplan should not breastfeed.
Can you take Zeplan with other medications?
You should tell your doctor about all other medicines you are taking or plan to use , including those without a prescription.
Two or more drugs taken concurrently may interact with each other and therefore their effects increase or namalyat.Izklyuchitelno important for your doctor to know if you are being treated with piklosporin , anticoagulants (warfarin , phenprocoumon or acenocoumarol ) , antifungals ( such as itraconazole or ketoconazole) , fibrates ( such as bezafibrate , fenofibrate and genfibrozil ) , antibiotics erythromycin and clarithromycin , HIV- protease inhibitors ( such as indinavir , nelfinavir , ritonavir , and saquinavir ) , antidepressant nefazodone or large doses ( more than 1 g per day ) or niacin nicotinic kiselina.Lekaryat may prescribe lower doses Zeplan , especially if you are taking cyclosporine , niacin or nicotinic acid, as well as some kidney diseases. Your doctor may adjust the dose of anticoagulant before, during , or after treatment with Zeplan.Ako patient takes Amiodaron or Verapamil and requires the inclusion of Zeplan , the dose of simvastatin should not exceed 20 mg dnevno.Tryabva to limit the consumption of grapefruit juice and avoid large amounts of alcohol while taking Zeplan .
What should be taken Zeplan ?
The doctor has prescribed Zeplan an appropriate dose for you. Follow the adoption of Zeplan until your doctor tells you to stop taking preustanovite.Ako Zeplan , your cholesterol may rise otnovo.Zeplan can be taken regardless of meals once a day - in the evening , unless your doctor prescribes otherwise.
What should you do if you miss a dose ?
Try to take Zeplan as prescribed. If you miss a dose , do not take an extra dose. Carry on as usual.
What should you do in case of overdose ?
Contact your doctor immediately .
What side effects may have Zeplan ?
Any medicine may have unintended or undesirable effects . Zeplan generally well tolerated . Most side effects are mild and transient. The most common adverse events were gastrointestinal disorders such as abdominal pain, constipation , diarrhea, vomiting , jaundice and hepatitis. Less common is the appearance of malaise and headache. The most frequently observed muscle pain, tenderness or weakness, liver problems and hypersensitivity ( allergic reactions, which may include symptoms such as joint pain , fever and difficulty breathing) . Because muscle problems rarely serious, immediate you should contact your doctor if you experience muscle pain, tenderness or weakness. It is also occasionally be side effects , such as anemia , cramps , flushing, urticaria , hair loss, dizziness , pancreatitis , neuropathy, paresthesia, and general malaise, but as with any prescription medicine , some side effects can be serious . Talk to your doctor or pharmacist for more information. They have a complete list of side reaktsii.Uvedomete your doctor or pharmacist if there is any unusual symptom , if any known symptoms persisted or worsened .
How should I store Zeplan ?
Store at temperatures below 25 ° C.
Keep all medicines out of the reach of children.