WEC eff. table. 500 mg. 10 table

WEC eff. table. 500 mg. 10 table
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WEC 500 effervescent tablets is an antibiotic belonging to the cephalosporin group of applied-to treat bacterial infections.

WEC eff. table. 500 mg. 10 table
 

What is WEC 500  effervescent tablets?

WEC  500 effervescent tablets is an antibiotic belonging to the cephalosporin group of applied-to treat bacterial infections.
  

What used WEC  500 mg effervescent tablets?

 
For the treatment of acute and chronic acute infections of varying severity caused by. cefaclor-susceptible bacteria and disease are suitable for receiving oral antibiotics.
 
To treat these infections are shown:
 The upper and lower respiratory tract 
 Ear, Nose and Throat - as otitis media (otitis media), sinusitis, tonsillitis (tonsillitis) and pharyngitis (sore throat)
  Kidney and lower urinary tract
  
When you must not take CJ 500  effervescent tablets?
 
You should not take CJ 500  if you are allergic to cefaclor to other antibiotics of this group (cephalosporins) or any of the ingredients
reactions to cephalosporins (cross-allergy).
What precautions should be taken when taking WEC  250 effervescent tablets?
Tell your doctor if you suffer from overt allergy or bronchial asthma, as can be expected allergic reactions to the product.
Tell your doctor if you suffer from severe gastrointestinal disorders, accompanied by vomiting and diarrhea, as in these cases is not providing adequate absorption and efficiency of WEC ® 500.
WEC  500 can have an effect on certain products that inhibit blood clotting (anticoagulants of the coumarin type). In such cases must be carefully monitored coagulation. If necessary, your doctor will reduce the dose of WEC .
If you need to examine your urine and / or blood, please tell your doctor that WEC ® 500, as certain tests can give inaccurate results (eg non-enzymatic method for the determination of glucose and protein in urine, Coombs test ).
1 effervescent tablet contains 17,2 mmol (398 mg). This should be taken into consideration if you are on a controlled sodium diet.
 
  
Other products that influence the effect of WEC  500 effervescent tablets or may be affected by the drug?
 
Tell your doctor if you are taking or have recently taken any medicines, even those not prescribed.
 

Antibiotics

 
WEC  500 should not be combined - as far as possible - with drugs that inhibit the growth of bacteria (eg, chloramphenicol, erythromycin, sulfonamides, or tetracyclines), since the effect of SES 500 can be reduced.
 
Probenecid (for the treatment of gout)
 
The additional use of probenecid results in the inhibition of the release cefaclor by the kidneys as a result of which receive higher concentrations of cefaclor and continued presence in the blood.
 
Anticoagulants
 
In patients receiving concomitant WEC ® 500 and medicines that inhibit blood coagulation (coumarin-type anticoagulants) were observed occasionally prolonged prothrombin time with or without bleeding Please note that these figures apply to the recently adopted drugs.
 
What food and drink should you avoid?
 
No information on foods and drinks that should be avoided.
  
How should consider children and adults following administration of WEC  500 effervescent tablets?
 
WEC  500 should not be used in premature infants, as there is insufficient clinical data.
 
What special precautions should be taken during pregnancy and lactation?
 
Observations in pregnant women have not shown evidence of fetal harm. Studies in animals have found embrio-/fetotoksichni effects.
However, in pregnancy, especially during the first three months of pregnancy WEC ® 500 should be taken only if the doctor deems it necessary, the treatment and after careful consideration of the benefit / risk ratio.
During lactation WEC  500 should be used only in particularly urgent need of treatment because the active ingredient may pass into breast milk. Infant may develop hypersensitivity to the active ingredient and there is diarrhea or intestinal mucosal colonization by fungi (eg blastomitseti).
 

 What to be aware when driving or operating machinery?

 
 So far it is not known to affect WEC  concentration and speed of response, but side effects such as low blood pressure or vertigo may increase the risk of a breach of these activities.
 
 
Dosage, method and duration of administration:
 
The following recommended dosage unless your doctor has prescribed WEC ® 500 effervescent tablets in a different dosing regimen. Please follow these instructions for use. Otherwise WEC ® 500 will not work correctly. 
 
How much and how often you take CEC  500 effervescent tablets?
 
Adults and children over 10 years, unless otherwise prescribed, should receive 1 effervescent tablet 3 times a day (corresponding to 500 mg of cefaclor three times daily).
The dose may be doubled in severe infections (such as pneumonia) or infections caused by less susceptible bacteria. In some cases, adults take up to 8 effervescent tablets (corresponding to 4 g daily cefaclor) and they were well tolerated. This dose should not be exceeded.
In mild infections such as uncomplicated infections of the lower urinary tract is
recommended 1/2 effervescent tablet 3 times a day (equivalent to 250 mg of cefaclor three times daily).
In the treatment of acute gonorrhea urethritis in men and women assigned dose of 6 effervescent tablets (corresponding to 3 g cefaclor), option combined with 1 g of probenecid.
 
Children 6 to 10 years, unless otherwise prescribed, should receive 1/2 effervescent tablet 3 times a day (equivalent to 250 mg of cefaclor three times daily).
In severe infections, inflammation of the middle ear (otitis media) or infections caused by less susceptible bacteria, a dose of 1/2 effervescent tablet four times a day (corresponding to 250 mg 4 times daily cefaclor).
Inflammation of the middle ear can also be treated with 1 effervescent tablet 2 times a day (equivalent to 500 mg two times daily cefaclor). In mild infections such as uncomplicated infections of the lower urinary tract is insufficient dosage of 1/2 effervescent tablet 2 times a day (equivalent to 250 mg of cefaclor 2 times a day).
Children under 6 years if no other prescription should take cefaclor 30 mg / kg bw / day in three divided doses (10 mg cefaclor / kg body weight three times a day).
In case of severe infections, otitis media, or infections caused by less susceptible pathogens, recommended 40 to 50 mg cefaclor / kg bw / day for a maximum of 1 g daily cefaclor. In case of otitis media, the total daily dose may be taken in two divided doses every 12 hours.
In mild infections such as uncomplicated infections of the lower urinary tract is insufficient dosage of cefaclor 20 mg / kg body weight / day divided in 2-3 divided doses every 8 or 12 hours.
Dosage in patients with impaired renal function
WEC  500 effervescent tablets can be applied even in patients with impaired renal function, without dose adjustment. Haemodialysis decreases serum half-life by 25-30%. In patients on regular hemodialysis before dialysis should be given a starting dose of 250 mg to 1 E. Maintenance dose taken between two dialysis is the same as in patients without dialysis.
  
 
When and how to take CJ 500  effervescent tablets?
 
Dissolve the effervescent tablet in a glass with 3-4 tablespoons of water, stir well and drink immediately. Then again, drink some water.
You can take CJ 500 ® effervescent tablets with a meal where absorption is not affected. 
How long can you take CEC  500 effervescent tablets?
 
In general, CEC  500 effervescent tablets should be taken 7 to 10 days, or at least 2-3 days after the symptoms disappear. When treating infections with beta-hemolytic streptococci is recommended duration of treatment at least 10 days to prevent late complications (eg rheumatic fever and glomerulonephritis).
The duration of application are determined by your doctor.
 
 
What should I do if CJ 500 effervescent tablets were taken in very large quantities (intentional or unintentional overdose)?
 
So far there are no reported cases of intoxication with cefaclor. If accepted large quantities of product, you should consult a doctor. Please keep the packaging of the drug to the doctor to determine the accepted active ingredient.
 
What should you do if you take more than the prescribed dose WEC  500 effervescent tablets or have missed taking the drug?
 
If you forgot accepted, please take your dose as soon as possible. If you take medication several times, you should consult your doctor to monitor the situation and take appropriate action.
 
What you should know if you have discontinued or have stopped it prematurely?
 
If you stopped treatment early, the risk of relapse.
 
What side effects can cause the application of WEC  500 effervescent tablets?
 
Like all medicines, use of SES  500 can cause side effects
 
Blood and blood cells
 
Very rarely were no changes in the number of blood cells (eosinophilia, leukopenia, lymphocytosis, thrombocytopenia, neutropenia, uncommon, and in some cases, aplastic and hemolytic anemia). These side effects are normalized spontaneously after treatment. Uncommonly, a significant decrease in white blood cells (agranulocytosis).
 
Liver and bile ducts
 
Uncommonly can Reversible increase in serum liver enzymes (transaminases, alkaline phosphatase).
Have been reported instances of transient liver cell damage (hepatitis) and breach outflow of bile (jaundice).
 
Gastrointestinal
 
Infrequent disturbances may occur as lack of appetite, abdominal pain, diarrhea, vomiting, stomach, nausea or loose stools. These events occur slightly and usually disappear during or after therapy interruption in.
 
As with other broad spectrum antibiotics, may cause intestinal inflammation (colitis), including psevdomemranozen colitis.
 
Kidneys and urinary tract
 
May occur uncommonly acute inflammation of the kidneys (acute interstitial nephritis), but it resolves after completion of therapy. It was also observed slight increase in blood urea and creatinine.
 
Nerves
 
Reported were infrequent cases of transient hallucinations, hyperactivity, nervousness, insomnia, drowsiness, dizziness or embarrassed behavior. As with other drugs of this group (cephalosporin antibiotics) can not be ruled out increased susceptibility to convulsions.
 

Hypersensitivity

 
Often possible allergic skin reactions (ie flushing a burning sensation (rash), itching, hives, swelling and blistering (urtikariyna exanthema), rash similar to measles (maculopapular, morbilliform exanthema).
Other symptoms of hypersensitivity reactions can increase the number of eosinophilic cells (eosinophilia), a positive test Coomb (detecting certain types of antibodies in the blood), (angioedema) edema, drug fever, and inflammation of the vagina.
Reported cases were uncommon, serum sickness, erythema multiforme (different manifestations of flushing) or above skin reactions accompanied by joint symptoms and fever. In these cases, unlike serum sickness, lymphadenopathy and proteinuria occurred very rarely. There are no circulating antibodies.
In general, these allergic reactions were observed during or after re-treatment with cefaclor (more common in children than in adults) and disappear within a few days after discontinuation.
Severe hypersensitivity reactions can be expressed by a fall in blood pressure to life-threatening shock, swelling of the face (facial edema) ', increased heart rate, swelling of the larynx to airways, difficulty breathing, swelling of the tongue. In individual patients, these reactions occurred after the first administration of the drug. In appearance they need immediate medical attention.
Uncommon cases of severe skin manifestations of common life-threatening reactions (such syndrome Stevens-Johnson, exfoliative dermatitis have been reported in association with administration of WEC ® 500 effervescent tablets
 
Other adverse reactions
 
After receiving SES 500 effervescent tablets occasionally been reported transient increases in blood pressure.
Prolonged or repeated use of cefaclor may result in a secondary infection (superinfection) and colonization with cefaclor-resistant bacteria or fungal infection (blastomitseti).
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
 
What measures should be taken in relation to side effects?
 
If during or after treatment with the drug is observed severe or persistent diarrhea, please consult your doctor as this may be a manifestation of a serious intestinal disease (pseudomembranous colitis), which should be treated immediately. Please do not take self with drugs inhibiting gastrointestinal motility. If you are experiencing sudden severe hypersensitivity reactions, please consult your doctor as you may need immediate treatment.
 
Storage Instructions:
 
The shelf-life of the drug is printed on the packaging.
Do not use after the expiry date stated on the packaging.
 

How should I store WEC  500 effervescent tablets?

 
Please keep in original container, tightly closed to protect from moisture.
Store at temperatures below 25 ° C.
Keep out of reach of children!
What is the active ingredient?
 
1 effervescent tablet contains 524.48 mg cefaclor monohydrate, equivalent to 500 mg cefaclor.
 
 
 
What else WEC contains 500 effervescent tablets?
 
citric acid, macrogol 6000. sodium cyclamate, sodium dihydrogen citrate, sodium hydrogen carbonate - sodium sulphate, povidone K 25, saccharin sodium, flavors (lemon).

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