Verapamil. 40 mg. 50 tablets
Verapamil. 40 mg. 50 tablets
Active substance : Verapamil hydrochloride 40 mg per tablet .
Excipients: Lactose monohydrate , wheat starch , silicon
colloidal anhydrous , gelatin , talc , magnesium stearate.
PHARMACEUTICAL FORM AND CONTENTS
Film-coated tablets of 40 mg, and 50 pieces in a package.
MANUFACTURER AND MARKETING AUTHORISATION
Sofiya1797 Blvd "KP . Ohridski " 3
Verapamil is a medicine belonging to the class of calcium antagonists. Inhibits the entry of calcium ions into smooth muscle cells of the arteries and heart muscle. This leads to a decrease in contractility of the heart muscle vasodilation and facilitate the work of the heart.
Verapamil is well absorbed in the digestive tract breaks down in the liver . The effect occurs 1-2 hours after its adoption and continued until 6:00 . Excreted primarily through the kidneys and few stools.
Treatment of arterial hypertension of different origin, ischemic heart disease (stable and unstable angina , angina pectoris after myocardial infarction , vasospastic angina) , heart rhythm disorders.
Hypersensitivity to any component of the product. Cardiogenic shock , acute myocardial infarction , hypotension, heart rate below 60 beats per minute , atrioventricular block, sick sinus syndrome node (bradycardia - tachycardia syndrome) , overt cardiac failure.
The product should be used with caution in hepatic or renal function. Verapamil dosage should be reduced in patients with impaired neuromuscular transmission ( Duchenne muscular dystrophy ) .
Attention! Verapamil medicinal product contains lactose - can be dangerous for people with lactase deficiency . The presence of wheat starch can be dangerous for people with celiac disease (gluten enteropathy ) .
Physician should be notified of all medicines with the patient. In concomitant use with other drugs that affect blood pressure, the dose of Verapamil be reduced by your doctor. The product should not be used with other drugs that affect heart rate (especially the products of the group of beta-blockers ) , carbamazepine , midazolam, anti-tumor agents . Verapamil inhibits significant release of alcohol in the body , leading to an increased concentration of the latter in the blood and increased toxicity.
Use in pregnancy and lactation
Should not be administered during the first 3 months of pregnancy . Crosses the placenta and is excreted in breast milk. During pregnancy and lactation verapamil can be given only if the potential benefit to the mother is greater than the possible risk to the fetus or infant. Impact on alertness and ability to drive at higher initial doses the risk of a sharp drop in blood pressure and dizziness, and therefore should be used with caution by drivers and machine operators .
Application and dosage :
The dosage and duration of treatment is determined by the attending physician . If it is not otherwise specified , using the following regimen of verapamil :
For adults with stable angina , treatment is initiated with 1 tablet 3 times daily and increased to 3 tablets 3 times a day , in unstable angina - from 6 to 12 tablets per day , divided into 3 or 4 times , for delaying the pulse at the atrial arrhythmia is taken in doses from 1 to 3 tablets every 6 hours for the lowering of blood pressure when administered at doses 2-3 tablets (up to 4 tablets) 3 times daily. In children over 14 years - For prevention and treatment of disturbances in sinus rhythm with tachycardia and hypertensive crises (including renal hypertension) 2-3 times daily 40-120 mg.
Upon acceptance of larger doses than prescribed , the patient should promptly consult your doctor .
SIDE EFFECTS :
Tolerance of the product is very good. In very rare cases occur: constipation, nausea , nervousness, tiredness at the beginning of treatment , vertigo , headache , lower blood pressure , heart failure , peripheral edema, cardiac arrest , AV- block , very rarely seen as rashes sensitization . STORAGE
In the original container at a temperature below 30 ° C. Keep out of reach of children !
SHELF LIFE : 5 ( five) years.