Valtrex. 500 mg. 10 tablets
Valtrex. 500 mg. 10 tablets
Valtrex WHAT IS AND WHAT IT IS USED FOR?
Valtrex in the form of film coated tablets. Each tablet contains 500 mg of active substance valacyclovir (valaciclovir), in the composition of the tablets includes the following inactive ingredients: microcrystalline cellulose, crospovidone, povidone K90, magnesium stearate, colloidal silicon dioxide, hydroxypropyl methylcellulose, titanium dioxide, polyethylene glycol 400, polysorbate 80, purified water, carnauba wax, and printing ink containing brilliant blue (E133). Each pack contains 10 tablets Valtrex.
Valtrex is an antiviral drug. Used in:
For the treatment of infections caused by herpes simplex virus in the skin and mucous membranes, including genital herpes
For the prophylaxis (prevention) of recurrent infections caused by the herpes simplex virus in the skin and mucous membranes, including genital herpes.
Herpes simplex virus induces the formation of small, fluid filled blisters that burst and replaced remain small, painful sores. Valtrex stops multiplication of the virus and the development of the infection and reduces the time during which the virus is released from the skin and mucous membranes. Reducing the number of painful blisters and helps for rapid recovery.
It is important to start treatment of the infection as much as possible in advance. If you start taking Valtrex at the first signs of infection, you can prevent completely the occurrence of bubbles.
If you have already had infections with herpes simplex virus, the doctor may prescribe Valtrex tablets to take each day to prevent new infections.
To reduce the risk of transmission of genital herpes when used in combination with safe sex (use of condoms).
For the treatment of herpes zoster
Herpes zoster is caused by varicella zoster virus. It is characterized by damage to the nerves and skin, which most often manifested by a painful skin rash along the nerve. Valtrex blocking viral replication and thus stops the infection and reduces its duration.
For the prevention of cytomegalovirus (CMV) infection and disease after renal transplantation
2. BEFORE YOU TAKE Valtrex
This medicine is suitable for many people, but still small 4ast them under certain conditions should not take or need specialist advice. Please tell your doctor if you:
- Have ever had symptoms of allergy to valacyclovir, acyclovir (another antiviral medicine) or any of the other ingredients of Valtrex.
- You are pregnant or trying to become pregnant
- breast feeding
- Have kidney disease
- Currently taking any other medicines, including mycophenolate mofetil, ciclosporin or tacrolimus?
If the answer to any of these questions is positive, let your doctor before taking the drug.
3. DOSAGE AND METHOD OF ADMINISTRATION
Take your medicine as your doctor prescribes. It is important that the drug be administered at a specific time. If you are not sure, check with your doctor.
For the treatment of herpes simplex infection the usual dose is 500 mg twice daily Valtrex for 5 days. In some cases, your doctor may decide that you need to take the medicine for 10 days. Take one tablet in the morning and one evening. For the treatment of labial herpes (cold sores) can be taken Valtrex 2 g twice daily for one day. The second dose is to be taken 12 hours (no more than 6 hours) after the first dose. When using this dosing regimen, treatment should not exceed one day, as it showed no additional clinical benefit. Treatment should be initiated at the first symptoms (eg tingling, itching or burning).
For the prevention of recurrent herpes simplex infections the usual dose is 500 mg once daily Valtrex. Patients with a weakened immune system (immunocompromised patients) the usual dose is 500 mg twice daily.
To reduce the risk of transmission of genital herpes dosage for infected partner is 500 mg once daily Valtrex. This therapy does not cure genital herpes and not completely eliminate the risk of its transmission through sexual contact, so it is recommended partners to take appropriate measures.
For the treatment of herpes zoster usual dose is 1000 mg (two tablets Valtrex 500 mg) three times a day for 7 days. Most people take one dose (2 tablets) in the morning after waking up, one dose (2 tablets) at lunch and one dose (2 tablets) at night before sleep. Even distribution of doses throughout the day will help to quickly master the rash and diskomfortyt.
For the prevention of cytomegalovirus (CMV) infection and disease usual dose for adults and children over 12 years is 2000 mg (four tablets Valtrex 500 mg) 4 times daily for 90 days. Administration should commence within 3 days (72 hours) after renal transplantation or as soon as you are able to swallow tablets. Your doctor may decide that you need to take the tablets for a longer period of time than the above.
If you suffer from severe kidney disease, your doctor may reduce the dosage of the drug. Your doctor may order blood tests to determine kidney function and depending on the results to adjust the dose of Valtrex are taking.
Take the tablets with some water. It does not matter whether you take it with or without food. It is important to drink plenty of fluids during treatment with Valtrex.
If you forget to take a tablet
If you forget to take a dose, do not worry. Take a dose as soon as you are remembered, and the next - at the right time.
If you take too much medicine
If you take too large a dose of Valtrex, or if someone else in your environment ingested the drug by mistake, immediately call your doctor or an ambulance.
Pregnancy and lactation
Valtrex should not be used during pregnancy only if the potential benefit of the drug to the mother outweighs the potential risk to the fetus.
Acyclovir, the major metabolite of valaciclovir, is excreted in breast milk. Caution is advised when administering Valtrex in nursing mothers.
Effects on ability to drive and use machines
There are no clinical studies to investigate the effect of Valtrex on ability to drive and use machines. Valtrex is unlikely to affect your ability to drive or operate machinery. Before you drive or operate machinery should check whether treatment with Valtrex or disease does not prevent you from doing it.
4. Undesirable effects
In most cases, Valtrex not cause adverse reactions.
In rare cases, the drugs can cause severe allergic reactions. If while you are taking Valtrex are experiencing any of these symptoms, contact your doctor or ambulance immediately:
sudden difficulty in breathing, speaking and swallowing; swelling of the lips, face and neck; severe dizziness or collapse (fainting); itching and skin rash.
Rarely Valtrex can cause disturbances in the blood (reduction of the number of white blood cells that protect against infection and decrease of blood platelet cells, which are involved in the process of blood clotting). Unless we get any of these side effects, tell your doctor immediately:
- Frequent and / or severe infections (especially sore throat)
- Unexplained rise in body temperature
- Ulcers in the mouth and / or throat
- Unusual bruising (bruises) or bleeding
- Small pinpoint red spots on the skin and / or mouth.
Unless we get any of these side effects, tell your doctor as soon as possible as possible:
- Stomach discomfort such as nausea, vomiting, diarrhea and pain;
- Skin rash (which may occur after exposure to ultraviolet light, such as at the beach or tanning beds);
There have been reports of the following adverse reactions occurred more frequently in patients with kidney disease or in people taking high doses of the drug for the prevention of CMV infection after renal transplantation:
Common side effects when taking Valtrex, which can occur in between 1 in 10 and 1 in 100 people include nausea and headache.
Uncommon side effects when taking Valtrex, which can occur in between 1 in 100 and 1 in 1000 persons include: difficulty breathing (dyspnea); rashes, sometimes caused by sensitivity to sunlight.
Rare side effects when taking Valtrex, which can occur in between 1 in 1000 and 1 in 10 000 individuals include:
- Discomfort in the abdomen
- Rash with nettles and fever, hives, itchy skin (pruritus / urticaria)
- Kidney disease
Very rare side effects when taking Valtrex, which may occur in less than 1 in 10 000 individuals include:
- Abnormal reduction in the number of white blood cells (leukopenia / neutropenia) *
- Increased bleeding and decreased ability for clotting (thrombocytopenia) *
- A rapidly developing severe allergic reaction (anaphylaxis) *
- Movements that can affect any part of the body (tremor)
- Lack of coordination (ataxia)
- Speech problems - unclear pronunciation (dysarthria) *
- Distorted relationship with reality (psychotic symptoms)
- Seizures (convulsions)
- A brain disorder (encephalopathy)
- Reversible elevations in liver function tests (see below)
- Swelling of the lips, eyes or tongue (angioedema) *
- Sudden / severe renal impairment
- Flank pain (in kidney)
If while taking the drug you notice any side effects not listed in this leaflet, please tell your doctor.
Valtrex can cause changes in liver function (which can be identified by examination of a blood sample). If changes occur due to Valtrex, do not worry as they return to normal after stopping the drug.
Do not store above 30 ° C.
Keep out of reach of children.
Do not take the medicine after the expiry date shown on the packaging.