VESISOL 10 mg. 30 tablets
The active substance of Vesisol belongs to a class of anticholinergic drugs. These drugs are used to reduce the activity of overactive bladder. This allows you to wait longer before you go to the bathroom and increases the amount of urine that the bladder can hold.
Vesisol is used to treat the symptoms of the disease called overactive bladder. These symptoms include: Homeric urge to urinate without prior warning, frequent urination or wetting if you can not go to the toilet in time.
2. What you need to know before taking Vesisol
Do not take Vesisol
if you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6);
if you can not urinate or empty your bladder completely (urinary retention);
if have severe gastrointestinal complaints (incl. toxic megacolon, a complication associated with ulcerative colitis);
if you suffer from the muscle disease called myasthenia gravis, which can cause extreme weakness of certain muscles;
if you suffer from increased pressure in the eye with a gradual loss of vision (glaucoma);
if you are undergoing dialysis;
if you have severe liver disease;
if you suffer from severe kidney disease or moderate liver disease while taking medications that can reduce the excretion of solifenacin in the body (eg. ketoconazole). In this case, your doctor will warn you.
Before starting treatment with Vezizol tell your doctor if you have or have had any of the above.
Warnings and Precautions
Talk to your doctor or pharmacist before taking Vesisol
if you have problems emptying the bladder (bladder outflow obstruction), or problems with urination (eg. a weak urine stream). The risk of an accumulation of urine in the bladder (urinary retention) is significantly greater;
if have obstruction of the digestive system (constipation);
if you are at risk of reduced activity of your digestive system (delayed motility of the stomach and intestines). Your doctor will tell you if such a risk exists;
if you suffer from severe kidney disease;
if have moderate liver disease;
if you have a hiatal hernia or heartburn;
if you have a nervous disorder (autonomic neuropathy).
Before starting treatment with Vezizol tell your doctor if you have or have ever had any of the above mentioned diseases.
Before starting treatment with Vezizol, your doctor will assess whether there are other reasons to urinate frequently (eg, heart failure (reduced pumping function of the heart) or kidney disease). If you have a urinary tract infection, your doctor will prescribe an antibiotic (medicine against certain bacterial infections).
Children and adolescents
Vesisol should not be used in children or adolescents under 18 years.
Other medicines and Vesisol
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
It is particularly important to tell your doctor if you take:
other anticholinergic drugs, desirable and undesirable effects of both drugs may increase;
cholinergic agents, as they may reduce the effect of solifenacin;
medications such as metoclopramide and cisapride, which make the digestive system work faster (solifenacin can reduce their impact);
drugs such as ketoconazole, ritonavir, nelfinavir, itraconazole, verapramil and diltiazem, which decrease the rate of degradation of solifenacin in the body;
drugs, such as rifampicin, phenytoin and carbamazepine, as they can increase the rate of degradation of solifenacin in the body;
drugs such as bisphosphonates, that can cause or exacerbate inflammation of the esophagus (esophagitis).
Vezizol with food and drink
Vezizol can be taken with or without food, depending on your preference.
Pregnancy and lactation
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.
You should not use Vesisol if you are pregnant, unless absolutely necessary.
Do not use Vesisol if breast-feeding as solifenacin may get into breast milk.
Driving and using machines
Solifenacin may cause blurred vision and sometimes sleepiness and fatigue. If any of these side effects should not drive or operate machinery.
Vezizol contains lactose
If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this product.
3. How to take Vesisol
Always take this medicine exactly as you have been told by your doctor. If you're not sure, ask your doctor or pharmacist.
The usual dose is 5 mg daily unless your doctor has told you to take 10 mg daily.
The tablets should be swallowed whole with some liquid. They can be taken with or without food, depending on your preference. Do not break the tablets.
If you take more dose Vesisol
If you take more dose Vesisol, or if a child has accidentally taken Vezizol, contact your doctor or pharmacist immediately.
Symptoms of overdose may include: headache, dry mouth, dizziness, drowsiness and blurred vision, seeing and hearing things (hallucinations), excitability, seizures (convulsions), difficulty breathing, rapid heart rate (tachycardia), accumulation of urine bladder (urinary retention) and dilated pupils (mydriasis).
If you forget to take Vesisol
If you forget to take a dose at the usual time, take it as soon as you remember unless it's time for your next dose. Never take more than one dose per day. If in doubt, always consult your doctor or pharmacist.
If you stop taking Vesisol
If you stop taking Vesisol symptoms of overactive bladder may come back or get worse. Always consult your doctor if you consider stopping treatment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Vesisol can cause side effects, although not everybody gets them.
If you get allergic attack or a severe skin reaction (eg. Blistering or peeling of the skin), you should immediately notify your doctor or pharmacist.
There are reports of angioedema (skin allergy that causes swelling of the tissues just below the skin) with airway obstruction (difficulty breathing) in some patients taking solifenatsinov succinate. If angioedema occurs, should immediately stop taking Vesisol and to conduct appropriate treatment and / or take appropriate measures.
Vesisol these can cause other side effects:
Very common (may affect more than 1 in 10 people):
Common (may affect 1 to 10 in 100 people):
constipation, nausea, indigestion with symptoms of bloating, abdominal pain, belching, nausea, heartburn (dyspepsia), stomach discomfort.
Uncommon (may affect up to 1 in 100 people):
urinary tract infection, bladder infection;
violation of the sense of taste (dysgeusia);
dry (irritated) eyes;
dry nasal passages;
reflux disease (gastroesophageal reflux disease);
fluid in the lower limbs (edema).
Rare (may affect up to 1 in 10,000 people):
Accumulation of a large amount of hardened feces in the colon (fecal obstruction);
increasing the amount of urine in the bladder due to failure to empty (urinary incontinence);
Very rare (may affect up to 1 in 10,000 people):
Not known (from the available data can not be estimated):
decreased appetite, high levels of potassium in the blood that can cause an irregular heartbeat;
increased intraocular pressure;
changes in the electrical activity of the heart (ECG), abnormal heartbeat (Torsade de Pointes);
violation of voice;
5. How to store Vesisol
Keep out of reach of children.
This medicine does not require any special storage conditions.
Do not use this medicine after the expiry date stated on the carton after "EXP". The expiry date refers to the last day of that month.
Do not dispose of medications in wastewater or household waste.
Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Contents of the pack and further information
The active substance is:
Vezizol 5 mg: Each tablet contains 5 mg solifenatsinov succinate, corresponding to 3,8 mg solifenacin.
Vezizol 10 mg: each tablet contains 10 mg solifenatsinov succinate, corresponding to 7,5 mg solifenacin.