VALZAP. H .160 mg.12.5 mg. 28 tablets

VALZAP. H .160 mg.12.5 mg. 28 tablets
€ 15.00
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VALZAP H tablet contains two active substances, valsartan and hydrochlorothiazide. Both medicinal matter, to help control hypertension.

VALZAP. H .160 mg./12.5 mg. 28 tablets 

 
 
WHAT VALZAP H AND WHAT IT IS USED

VALZAP H tablet contains two active substances, valsartan and hydrochlorothiazide. Both medicinal matter, to help control hypertension.

? Valsartan belongs to the group of medicines called blockers of angiotensin II receptors which help to control high blood pressure. Angiotensin II is a substance produced by the body and causes vasoconstriction. This leads to an increase in blood pressure. Valsartan works by blocking the effect of angiotensin II. This leads to dilation of blood vessels and lowering blood pressure.

? Hydrochlorothiazide is a diuretic (also known as "water tablets"), which reduces the amount of salt and water in the body by increasing the amount of urine. During prolonged use helps to lower and control high blood pressure.

VALZAP H is used to treat high blood pressure (hypertension), the condition is not adequately controlled by the administration of valsartan alone. High blood pressure increases the workload of the heart and arteries. If left untreated, it can damage the blood vessels of the brain, heart and kidneys, leading to stroke, heart failure or renal failure. High blood pressure increases the risk of heart attack. The decrease in blood pressure to normal levels reduces the risk of these diseases razvivanv.

2. BEFORE YOU TAKE VALZAP H

Do not take VALZAP H

? if you are allergic (hypersensitive) to valsartan, hydrochlorothiazide, sulfonamide derivatives (substances chemically related to hydrochlorothiazide) or any of the other ingredients of VALZAP H

? if you are pregnant after the third month of pregnancy (it would be better to avoid VALZAP H in early pregnancy - see. Section "Pregnancy and lactation")

? if you have severe liver disease

? If you have severe kidney disease

-If you have problems with urination

• If you are being treated with an artificial kidney (hemodialysis)

? despite treatment if you have low levels of potassium or sodium in the blood and too high levels of calcium

? If you have gout

Take special care with VALZAP H

? if you are taking medicines that increase the amount of potassium in the blood. These include potassium supplements or salt substitutes containing potassium, potassium-sparing medicines and heparin. You may need checking the amount of potassium in your blood at regular intervals.

-If the levels of potassium in your blood are low

? if you have diarrhea or severe vomiting

-If you are taking high doses of water pills (diuretics)

? If you have severe heart disease

-If you have a narrowing of the renal artery

-If you have recently undergone kidney transplantation (received a new kidney)

? If you suffer from aldosteronism. It is a disease in which the adrenal glands produce large amounts of the hormone aldosterone. If this is applicable to you, not recommended for use VALZAP H

? if you have liver or kidney disease

? if fever, rash and joint pain, which may be symptoms of systemic lupus erythematosus (SLE, a so-called autoimmune diseases)

? Aki suffer from diabetes, high levels of cholesterol, fat or uric acid in the blood

? if you have had allergic reactions with use of other blood pressure lowering agents of this class (blockers of angiotensin-ll receptor) or if you have other allergies or asthma.

You should tell your doctor if you are (or might become) pregnant. VALZAP H is not recommended for use in early pregnancy and may seriously harm your baby after 3 months of pregnancy (see section "Pregnancy and lactation"). VALZAP use of H can lead to positive doping control because the hydrochlorothiazide. If any of these is applicable to your condition, tell your doctor before taking VALZAP N.
 Taking other medicines

Please tell your doctor or pharmacist

 if you are taking or have recently taken any other

medicines, including medicines obtained without a prescription.

The treatment effect may be impaired if VALZAP H is taken with certain other medicines. You may need a dose adjustment or in some cases, discontinuation of a drug. This is especially true for the following drugs:

- Lithium, a medicine used for the treatment of

depression

? medicines that affect or may affect the level of potassium in the blood, medicines to control heart rhythm such as digoxin, potassium supplements or salt substitutes containing potassium, potassium-sparing medicines, other drugs that may increase or decrease the amount of potassium in the blood such as heparin corticosteroids

 some laxatives

- Other diuretics (water tablet), medicines for gout such as allopurinol, vitamin D and calcium supplements, drugs for treatment of diabetes (insulin or oral preparations).

• other medicines to lower blood pressure, such as beta-blockers or methyldopa, or drugs that constrict blood vessels

or stimulate the heart to adrenaline or noradrenaline

? medicines that raise the blood glucose level as diazoxide

? drugs for the treatment of cancer such as cyclophosphamide or methotrexate

• painkillers

• medicines used to treat arthritis

? medications to relax the muscles as tubocurarine

? anti-cholinergic drugs such as atropine or

biperiden

? amantadine (a medicine to prevent flu)

Cholestyramine and colestipol ? (lerastva used for the treatment of high levels of blood fats)

? cyclosporine, a drug administered in organ transplantation to prevent organ rejection

? some antibiotics (tetracyclines), anesthetics and sedatives.

Taking VALZAP H with food and drink

You can take VALZAP H with or without food.

Alcohol may cause further

lowering blood pressure and / or increasing

the risk of dizziness or fainting.

Children and young people (under 18 years)

Not recommend the use of H VALZAP in children
and youth.

Adults (65 and over)

You can use VALZAP H if you are aged 65 or more.
Pregnancy and lactation

Ask your doctor or pharmacist before taking any medicine.

• Be sure to tell your doctor if you think you are (or might become) pregnant.

Your doctor will normally advise you to stop taking VALZAP H before you become pregnant or as soon as you become pregnant and will advise you to take another medicine instead VALZAP N. VALZAP H is not recommended in early pregnancy, and must not be taken after the 3rd month of pregnancy because it may cause serious harm to your baby if used after 3 months of pregnancy.

• Tell your doctor if you are breast-feeding or breast-feeding, VALZAP H is not recommended for mothers who are breast feeding, and your doctor may choose another treatment for you. If you wish to breast-feed, especially if the child is a newborn or preterm.
Driving and using machines

No studies on the effect of valsartan / hydrochlorothiazide on ability to drive and use machines. Like other medicines used to treat high blood pressure, rarely VALZAP H may cause dizziness and affect the ability to concentrate. Before you drive, use tools or perform other activities that require concentration. make sure you know how you act VALZAP N.

Important information about some of the ingredients

VALZAP H contains lactose and sorbitol - both sugars. If your doctor has told you that you have an intolerance to some sugars, talk to him / her before taking this medicine. One dose of the medicinal product contains less than 1 mmol sodium (23 mg), i.e. he is "without sodium".

3. HOW TO TAKE VALZAP H

Always take VALZAP H exactly as your doctor tells you. This will help you achieve the best results and to reduce the risk of side effects. If you are not sure, ask your doctor or pharmacist.

People with high blood pressure often do not notice the signs of this problem. Many of them feel normal. This makes regular check ups important, even if you feel well. Your doctor will tell you exactly how many tablets VALZAP H should take. Depending on how you react to treatment, your doctor may reduce or increase the dose.

? H VALZAP usual dose is one tablet daily

? Do not change your dose or stop taking the tablets without consulting your doctor

• The medicine should be taken at the same time of day, usually in the morning

? You can take VALZAP H with or without food

? Swallow the tablet with a glass of water

If you take more than the amount of H VALZAP

If you accidentally taken too many tablets, contact your doctor, pharmacist or hospital.
If you experience severe dizziness and / or fainting, lay down and immediately contact your doctor. If you forget to take VALZAP N If you forget to take this medication, take your dose as soon as you remember. However, if it is almost time for your next dose, skip the one you forgot to take.

Do not take a double dose to make up for a missed dose.

If you stop taking VALZAP H

Stopping the use of VALZAP H may worsen your condition. Do not stop taking your medicine unless your doctor has told you.

If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, VALZAP H can cause side effects, although not everybody gets them. The following side effects have been observed on active substances valsartan and hydrochlorothiazide (active substances VALZAP H). Some of these side effects can be similar to symptoms caused by your specific condition. Others may not occur, and are not related to your therapy. Some symptoms may be serious and need immediate medical attention:
You should see your doctor immediately if you experience symptoms of angioedema, such as:

? swollen face, tongue or necked

? difficulty swallowing

? hives and difficulty breathing
Other side effects include:
Typically, the frequency of adverse events are defined as follows:

very common: affects more than 1 user in 10 common: affects 1 to 10 users in 100 uncommon: affects 1 to 10 patients in each 1000 rare: affects 1 to 10 users per 10 000

very rare: affects less than 1 in 10,000 patients

not known: frequency can not be

estimated from the available data.

Common:

-Inflammation of the nose and throat • diarrhea

-Fatigue
Uncommon:

? infection of the upper airways

? UTI

-Viral infections, rhinitis

? dizziness

? worsening vision

? pains in the abdomen and chest

? cough

? nausea

? heartburn (stomach upset) after meals

? pain in hands and feet

? sprains and strains

? stiffness

? strong urge to urinate

-Aberrant results in tests of renal function


? Low levels of potassium or sodium in the blood

Rare:

? vertigo

? tinnitus

? Low blood pressure

? muscle pain and muscle weakness

? sweating
Very rare:

? low platelet count, which leads to easier karveneinaranyavane

? low levels of red blood cells

? swelling of the face, lips, tongue or throat which may cause difficulty in breathing, swallowing or speaking

? irregular heartbeat

? rash

? itching

? inflammation of the blood vessels in the skin

? bleeding

? general swelling

? Hair Loss

Side effects seen with valsartan and hydrochlorothiazide separately, but VAL3AP H were observed:
Some symptoms may be serious and need immediate medical attention: Hydrochlorothiazide, one of the active substances VALZAP H may rarely affect the white blood cells, which reduces resistance to infections. If you get an infection with symptoms such as fever with deterioration of general condition, or fever and signs of local infection such as sore throat, mouth or urinary problems, contact your doctor. It is necessary to take a blood sample, to exclude the lack of white blood cells (agranulocytosis). It is important to tell your doctor about your treatment.
Other adverse effects:
Valsartan:
Uncommon:

? back pain

? inflammation of the sinuses

? weakness

? watery eyes, and itching

-Redness and swelling

? nosebleeds

? sad mood (depression)

• muscle cramps

-Sleep disorders Rare:

• Severe stabbing or dull pain around individual nerves

Very rare:

-Pain in the stomach such as gastritis, or gastric irritation

Joint pain

? impaired renal function

Hydrochlorothiazide:

Common:

? itchy rash and other types of rash

? lack of appetite

? less nausea and vomiting

? dizziness

- Fainting

? impotence
Rare:

? swelling or blistering of the skin (due to increased sensitivity to the sun)

? constipation

? discomfort in the stomach or intestines

• disorders of the liver (yellow skin or eyes)

? irregular heartbeat

? Headache

? Sleep Disorders

? light-colored urine

? sad mood (depression)

? tingling or numbness in the hands or feet

? visually impaired

? reduced levels of platelets (sometimes with bleeding and subcutaneous injuries)

Very rare:

? blood vessel inflammation with symptoms such as rash, purple with red spots, fever

Itching or redness of the skin

-Blistering of lips, eyes or mouth, skin peeling

? temperature

-Facial rash associated with joint pain

? muscular disorders, fever (cutaneous lupus erythematosus)

? severe pain in the upper stomach

-Absence or low levels of various blood cells

• severe allergic reactions

• difficulty in breathing

? lung infection

• shortness of breath

If any of the side effects gets serious, or if you notice any side effects not mentioned in this leaflet, please tell your doctor or pharmacist.

5 HOW LA STORE VALZAP H

-Keep out of the reach of children.

-Do not use VALZAP H after the expiry date stated on the carton / blister. The expiry date refers to the last day of that month.

? Do not store above 30 ° C. Store in the original package to protect from moisture.

• Do not use VALZAP H in damaged packaging or if there should have been a fake.

• Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment

6. FURTHER INFORMATION What VALZAP H

The active substances are valsartan and hydrochlorothiazide.

Each tablet VALZAP H 80 mg. / 12.5 mg contains 80 mg. valsartan and 12.5 mg.

hydrochlorothiazide.

(Each tablet VALZAP H 160 mg. / 12.5 mg contains 160 mg. Valsartan and 12.5 mg. Hydrochlorothiazide.

Each tablet VALZAP H 160 mg. / 25 mg contains 160 mg. valsartan and 25 mg. hydrochlorothiazide.) Other ingredients include:

• Core: Microcrystalline cellulose, silica colloidal anhydrous, sorbitol (E420), magnesium carbonate, pre-gelatinized starch, povidone K-25, sodium stearyl fumarate, sodium lauryl sulfate, crospovidone (Kollidon CL)

-Coating: lactose monohydrate, hypromellose, makrogop 4000, titanium dioxide (b 1/1) iron

oxide yellow (E172) (only stock 160 mg. / 25 mg.), a mixture of black, red and yellow iron oxide (E 172) (only stock 160 mg. / 25 mg., and 160 mg. / 12.5 mg.), iron oxide red (E172) .
 
 
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