Terbinafine. 250 mg. 28 table

Terbinafine. 250 mg. 28 table
€ 42.00
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Myconafine "is a synthetic product. Antifungal Its effect is due to inhibition of enzymes that play a key role in the formation of important fungal substances. Depending on the concentration, the product can destroy fungal cell



Table terbinafine. 250 mg. 28 table
 

WHAT Myconafine "AND WHAT IT IS USED

Myconafine "is a synthetic product. Antifungal Its effect is due to inhibition of enzymes that play a key role in the formation of important fungal substances. Depending on the concentration, the product can destroy the fungal cell.
 

Myconafine is used to treat:

 
 onychomycosis (nail fungal infection) of the hands and feet caused by dermatophytes;
  Tinea capitis (fungal infection of the scalp);
  Fungal infections of the skin caused by dermatophytes;
  Mycosis of smooth skin - tinea corporis (body), tinea cruris (a calf), tinea pedis (on foot);
 Skin infections caused by organisms of the genus Candida (eg Candida albicans).
 
Unlike local forms of product Myconafine "tablet is not effective against Pityriasis versicolor.
 

 WHAT YOU NEED TO KNOW BEFORE TREATMENT WITH Myconafine

 
Product is used in hypersensitivity to Myconafine. "
 
In this medicinal product, please note the following:
 
The product is used with caution in patients with chronic or active liver disease. Prior to treatment is necessary to evaluate existing liver disease. In these cases, hepatotoxicity may occur.
 
Patients should be advised to monitor unexplained symptoms of nausea, anorexia, pain in the right upper abdominal pain or jaundice, dark urine and fatigue. In patients with pre-existing renal disease (creatinine clearance <50 ml / min) administration has not preporachva.Lechenieto the product should be discontinued at the onset of progressive morbilliform obriv.Ryadko can meet and skin reactions like syndrome Stevens-Johnson and toxic epidermal necrolysis, which also require discontinuation of therapy.
 
During treatment with Myconafine "can be found in the eye lens changes and retina.
 
In patients with immune deficiency necessary blood counts, particularly when treatment continues for more than six weeks. Upon the occurrence of secondary neutropenia (neutrophil count <1000 kl./mm3) treatment product is discontinued and appoint appropriate treatment.
 
Application Myconafine "when taking food and drink
 
Taking the product is not affected by food and drink.
 

Pregnancy

 
Before taking any medicines, check with your doctor or pharmacist
 
Since the treatment of nail fungus (onychomycosis) may be delayed, treatment is not recommended during pregnancy.
 
Breastfeeding
 
Before taking any medicines, check with your doctor or farmatsevtSled product acceptance he found in breast milk. The ratio between the amount in milk and plasma is 7:1 and therefore not be used during breastfeeding.
 

Driving and operating machinery

 
Myconafine "does not affect the ability to drive and use machines. Taking other lekarstvaMolya, tell your doctor or pharmacist if you are taking or have recently taken any other medicines, even if they have not been prescribed by a doctor
  Effect of other medicinal products on terbinafine - separation of terbinafine may be accelerated by drugs that increase metabolism and can be inhibited by drugs that inhibit the metabolism of certain enzymes in the liver (P450 enzyme system). In these cases it may be necessary to adjust dozata.Tsimetidin reduces the release of terbinafine by 33%. Rifampicin enhances separation by 100%.
  Effect of terbinafine on other drugs - not affect the excretion of antipyrine and digoxin. Terbinafine may increase the effects of caffeine by 19%.
 
Terbinafine inhibits the metabolism of products mediated by CYP2D6 tricyclic antidepressants, beta-blockers, selective serotonin reuptake inhibitors, antiarrhythmics class 1C products and MAO inhibitors Type B. It increases the clearance of desipramine by 15%. Terbinafine may reduce the effect of cyclosporine by 15%.
 

HOW TO APPLY Myconafine

 
Always Myconafine as your doctor! On prescription! The product is administered orally.
 Adults - 250 mg once daily.
 
Children over 2 years depending on the weight
<20 kg - 62,5 mg once daily (half tablet of 125 mg); 
20 to 40 kg - 125 mg once daily;
> 40 kg - 250 mg once daily.
The duration of treatment depends on the cause and location of the infection:
  In onychomycosis treatment arms still 6 weeks to 3 "months and with onychomycosis of the feet - 3 to 6 months, while abnormal growth of the nail may be needed longer treatment;
  Tinea capitis - 4 weeks;
  Skin infection - tinea pedis (interdigitalna, plantar type "loafers") - 2 to 6 weeks; tinea corporis, cruris-2 to 4 weeks;
  For smooth skin infections by dermatophytes and Candida skin - 2-4 weeks.
 
Elderly
 
There is no evidence that these patients require different dosages or the side effects of it are different from those in younger patients. We take into account the possibility of altered renal and hepatic function in these patient
 
If you take too much of the drug:
 
When taking a higher dose than prescribed immediately seek help from a doctor! Data Myconafine ® overdose is limited. Up to 5 g (20 times the therapeutic dose) were administered without serious adverse reactions. Symptoms usually include nausea, vomiting, abdominal pain, confusion, rash, frequent urination, headaches.
 
Recommended elimination of the product with activated charcoal and symptomatic therapy.
 
If you forget to Myconafine:
 
If you forget to take the next dose, take the missed dose as soon as possible, but do not take both to the next.
 

 POSSIBLE SIDE EFFECTS

 
Like all medicines, Myconafine can cause adverse reactions reaktsiiNezhelanite are ranked by frequency according to the following classification:
 
very common> 1/10, common> 1/100 to <1/10;
 
uncommon> 1/1000 to <1/100;
 
Rare> 1/10000 to <1/1000;
 
very rare <1/10000.
 
Blood and lymphatic system
 
Very rare
 
Neutropenia, agranulocytosis, thrombocytopenia
 
Immune System
 
Very rare
 
Anaphylactoid reactions (including angioedema), skin and systemic lupus erythematosus
 
Nervous system and psychiatric disorders
 
Common
ncommon
 
Headache
 
Disorders of taste loss, which is reversible after cessation of treatment, disturbed food intake
 
Gastrointestinal Disorders
 
Very common
 
Gastrointestinal symptoms - stomach fullness, loss of appetite, dyspepsia, nausea, mild abdominal pain, diarrhea
 
Hepatobiliary disorders
 
Rare
Hepato-biliary dysfunction, rarely liver failure
Skin and underlying tissues
Very common
Very rare
Non-serious forms of skin reactions (rash, urticaria) Serious skin reactions - Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized pustular psoriasis exanthemous-like attacks and exacerbation of psoriasis, hair loss, without any causal connection
 
Musculoskeletal, connective tissue and bone disorders
 
Very common
 
Musculoskeletal effects - arthralgia, myalgia
 
General disorders
 
Very rare
 
Fatigue
 
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. 
 

 STORAGE CONDITIONS

 
No special storage conditions. Keep out of reach of children! Do not use after the expiry date stated on the package! _Srok Life: three (3) years
Active substance in one tablet: Terbinafine hydrochloride, eq. Terbinafine 125 mg of
 
Active substance in one tablet: Terbinafine hydrochloride, eq. Terbinafine 250 mg of
 
Excipients: microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, hydroxypropyl methylcellulose-, magnesium stearate.

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