Table irbesartan. 300 mg. 28 tablet

Table irbesartan. 300 mg. 28 tablet
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Irbesartan Accord belongs to a group of medicines called receptor antagonists for angiotensin-II.

Table irbesartan. 300 mg. 28 tablets
 

WHAT irbesartan ACCORD AND WHAT IT IS USED

Irbesartan Accord belongs to a group of medicines called receptor antagonists for angiotensin-II.
Angiotensin-II is a substance produced in the body which binds to receptors in blood vessels causing them to constrict. Thereby increasing blood pressure. Accord Irbesartan prevents the binding of angiotensin-II to these receptors, thus blood vessels relax and blood pressure is lowered. Irbesartan Accord prevents deterioration of renal function in patients with hypertension and type 2 diabetes.
 
Irbesartan Accord used:
 to treat high blood pressure (hypertension);
 to protect the kidney in patients with high blood pressure, type 2 diabetes and laboratory evidence of impaired renal function.
 

 BEFORE YOU TAKE Irbesartan ACCORD

 
Do not take Irbesartan Accord:
 If you are allergic (hypersensitive) to irbesartan or any other ingredients of Irbesartan Accord;
 If you are in the second or third trimester of pregnancy;
 If you are breastfeeding.
 
Irbesartan Accord should not be taken by children and teenagers under 16 years of age.
 
Take special care with Irbesartan Accord:
Tell your doctor before taking Irbesartan Accord if:
 Suffer from severe vomiting or diarrhea;
 Have kidney disease;
 Suffer from heart disease;
 Receive Irbesartan Accord of diabetic nephropathy. In this case, your doctor may order laboratory tests, especially for measuring the levels of sodium in the blood in cases of impaired renal function.
 Suffer from primary aldosteronism, a condition in which your adrenal glands produce too much hormone aldosterone reason to retain sodium and potassium wasting.
 Suffering from arterial stenosis (narrowing or blockage of the artery that supplies blood to the kidneys).
 
Taking other medicines:
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Irbesartan Accord usually do not interact with other medications.
You have to do laboratory tests if you are taking:
 potassium supplements;
 salt substitutes that contain potassium;
 Potassium-sparing medicines (such as certain diuretics);
 Drugs that contain lithium.
 
 
If you take certain painkillers called non-steroidal anti-inflammatory drugs, the effect of irbesartan may be reduced.
 
Irbesartan Accord with food and drink
Irbesartan Accord tablets can be taken with or without food. Tablets should be swallowed with water.
 
Pregnancy and lactation:
Ask your doctor or pharmacist before taking any medicine. Tell your doctor if you are pregnant or plan to become pregnant. Your doctor will normally advise you to take another medicine instead of Irbesartan Accord as Accord Irbesartan is not recommended in early pregnancy and may cause serious harm to your baby if used after the third month of pregnancy. Appropriate antihypertensive drug usually must replace Irbesartan Accord before pregnancy. The product should not be used during the 2nd and H rd trimester of pregnancy or during lactation.
Your doctor will normally advise you to stop taking Irbesartan Accord as you know you are pregnant. If you become pregnant during treatment with Irbesartan Accord, please tell your doctor and see him immediately.
 
Breastfeeding
You should not take Irbesartan Accord if you are breastfeeding (see "Before you take Irbesartan Accord").
 
Driving and operating machinery
No studies on the effects on ability to drive and use machines. Irbesartan Accord is unlikely to affect your ability to drive or operate machinery. Sometimes it may appear dizziness or fatigue during the treatment of high blood pressure. If you feel, you should consult your doctor before performing these activities.
 
Important information about some of the ingredients of Irbesartan Accord
This medicinal product contains lactose. If your doctor tells you that you have an intolerance to some sugars, contact your doctor before taking this medicine. Patients with rare hereditary enzyme defects of galactose intolerance, hereditary lactase deficiency or poor absorption of glucose and galactose should not use this product.
 

 HOW TO TAKE Irbesartan ACCORD

 
Always take Irbesartan Accord exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.
The usual dose is 150 mg once daily. In the course of treatment the dose may be increased to 300 mg once daily, depending on the blood pressure. Optimal blood pressure will be reached by 4 to 6 weeks after initiation of therapy.
In patients with hypertension and type 2 diabetes, 300 mg once daily is the recommended maintenance dose for treatment of related kidney disease.
Your doctor may recommend a lower dose, especially when starting treatment in certain patients, such as patients on hemodialysis or patients older than 75 years.
Irbesartan Accord tablets are for oral use. The tablets should be swallowed with a sufficient amount of fluid (eg one glass of water). You can take Irbesartan Accord with or without food. You should try to take your daily dose at one time each day. It is important to continue to take Irbesartan Accord until your doctor tells you to stop or change treatment.
 
If you take more Irbesartan dose Accord
If you accidentally take more tablets than your doctor has appointed nezabavnose contact your doctor or go to the nearest hospital. Symptoms of overdose include a sharp drop in blood pressure (hypotension) and fast heartbeat (tachycardia).
 
If you forget to take Irbesartan Accord
If you accidentally miss a daily dose, just take the next dose as usual. Do not take a double dose to make up for a missed dose.
 
If you stop taking Irbesartan Accord:
Do not discontinue treatment without consulting your doctor. It is important to take Irbesartan Accord as long as your doctor has prescribed. This will keep your blood pressure within normal limits and / or to protect your kidneys from damage.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
 

 POSSIBLE SIDE EFFECTS

 
Like all medicines, Irbesartan Accord can cause side effects, although not everybody gets them.
In each group, depending on the frequency of adverse reactions are presented in order of decreasing seriousness.
 
Adverse reactions are ranked by frequency as follows:
Very common: More than 1 in 10 patients;
Common: 1 to 10 of 100 people;
Uncommon: 1 to 10 of 1000 patients treated;
Rare: 1 to 10 of 10,000 patients treated;
Very rare: less than 1 in 10,000 patients treated.
 
Very common:
  If you suffer from high blood pressure and diabetic nephropathy in type 2 diabetes, your doctor will notice an increase in potassium levels in the blood.
 
Common:
 Dizziness;
 Nausea / vomiting and fatigue;
 In patients with hypertension and diabetic nephropathy in type 2 diabetes were also reported dizziness when getting up from a lying or sitting position, low blood pressure when you stand up from a lying or sitting position, and pain in the joints or muscles;
 Unusual changes in your blood chemistry and increased creatine kinase;
 If you suffer from high blood pressure and diabetic nephropathy in type 2 diabetes, your doctor will notice a decrease in hemoglobin.
 
Uncommon:
 Palpitations;
 Flushing;
 Cough;
 Diarrhea;
 Indigestion / heartburn;
 Sexual dysfunction (problems with sexual performance);
 Chest pain.
 
Some side effects have been reported since marketing of Irbesartan Accord, but the frequency with which they occur is not known. These side effects are:
 Headache;
 Taste disturbance;
 Tinnitus;
 Muscle spasms
 Pain in the joints and muscles;
 Abnormal function of the kidneys.
 Elevated levels of potassium in your blood;
 Impaired renal function;
 Inflammation of small blood vessels mainly affecting the skin (a condition known as leukocytoclastic vasculitis).
 
Like other similar medicines, rare cases of allergic skin reactions such as:
 Rash;
 Hives (urticaria);
 Localized swelling of the face, lips and / or tongue
 
have been reported in patients taking irbesartan. If you are having a reaction, or you short of breath, stop taking Irbesartan Accord and seek immediate medical attention.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
 

 HOW TO STORE irbesartan ACCORD

 
Keep out of reach of children.
Do not use Irbesartan Accord after the expiry date stated on the carton and blister. The expiry date refers to the last day of that month.
This product does not require any special storage conditions.
Do not remove the tablet from the blister until you are ready to take the medicine.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
                                                                

 ADDITIONAL INFORMATION

 
What Irbesartan Accord:
The active substance is irbesartan: Each tablet contains 300 mg of irbesartan.
The other ingredients are:
Tablet core: lactose monohydrate, croscarmellose sodium (E468), microcrystalline cellulose (E460), hypromellose E5 (E464), colloidal silica anhydrous (E551), magnesium stearate (E572).
Film coating: hypromellose E5 (E464), macrogol 400, lactose monohydrate, titanium dioxide (E171).
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