TRANSMETIL 10 tablets 500 mg

TRANSMETIL   10 tablets   500 mg
€ 28.00
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Your medicine is called Transmetil. Its active ingredient normally found in many organs and tissues of the human body and plays an important role in many biological processes. In the liver ademetionin support mechanisms to prevent the occurrence of cholestasis (accumulation of bile).



TRANSMETIL - 10 tablets - 500 mg
 

TRANSMETIL WHAT IS AND WHAT IT IS USED

Your medicine is called Transmetil. Its active ingredient normally found in many organs and tissues of the human body and plays an important role in many biological processes. In the liver ademetionin support mechanisms to prevent the occurrence of cholestasis (accumulation of bile). In liver cirrhosis, a significant decrease of ademetionina in the liver, which in turn carries the risk of occurrence of cholestasis. Application of ademetionin in patients with cirrhosis leads to recovery of its quantity and thus prevents the stagnation of bile (bile).
 
Transmetil is used to treat cholestasis in the liver in patients with cirrhosis pretsirotichno condition.
 
This medicine is used to treat cholestasis in the liver during pregnancy.
 

 BEFORE YOU TAKE TRANSMETIL

 
You should not take this medicine if you are hypersensitive to the active substance (ademetionin) or any of the inactive ingredients in the tablet.
 
Take special care with Transmetil
 
In pretsirotichni and cirrhotic conditions with elevated levels of ammonia in the blood, treatment should be done under supervision of a physician in the course of certain studies. Gastro-resistant tablets should be removed from the blister immediately before use. They should not be chewed and swallowed to use. For better absorption of the active substance in Transmetil and achieve greater treatment effect, the tablets should be taken before and after meals. If the tablets are colored in a different color other than white, which may be due to the integrity of microscopic blisters (Membrane), the entire package must be returned and replaced with another.
 
Some patients may appear dizziness application of ademetionin. Patients should be advised not to drive or operate machinery during treatment until you are sure that the product does not affect their ability to perform these activities.
 
Taking drugs druri
 
No evidence of interaction with other drugs Transmetil. However, please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
 
Caution is advised when concomitant intake of ademetionin with selective inhibitors of serotonin reuptake (SSK1), tricyclic antidepressants (such as clomipramine) medicines obtained without a prescription containing tryptophan.
 

Pregnancy and lactation

 
The use of high doses ademetionin women in the last three months of pregnancy did not lead to side effects. It is recommended that the product be used in the first three months of pregnancy only if absolutely necessary.
 
Ademetionin should be used during lactation only if the potential benefit outweighs the risk to the infant.
 

Driving and operating machinery

 
Some patients may appear dizziness application of ademetionin. Patients should be advised not to drive or operate machinery during treatment until you are sure that the product does not affect their ability to perform these activities.
 

 HOW TO USE TRANSMETIL

 
Always Transmetil exactly as your doctor has told you. If you are unsure ask your doctor or pharmacist.
Treatment can start with the use of injectable and oral form and to continue with the oral form of the product.
Ademetionin tablets are available as 500 mg. They should be swallowed whole and not chewed.
For better absorption of the active substance and full healing effect ademetionin tablets should be taken with food.
 
Tablets should not be removed from the blister immediately before use. If the tablets are a different color other than white (due to breakthroughs in the aluminum shell) is not recommended their adoption.
 
Cholestasis in the liver
 
The recommended daily dose for relief of the signs of stagnation and chronic liver disease, regardless of the reason is 500-1000 mg intravenous and / or intramuscular and 1000-1500 mg for oral administration.
 Initial treatment - 1 to 2 bottles a day (equiv. to 500 to 1000 mg daily) intravenously or intramuscularly for two weeks.
Maintenance treatment - 1000-1500 mg daily taken orally.
 
Elderly
 
Dose selection for an elderly patient should be approached cautiously, as you usually have to start with low doses to the greater frequency of decreased hepatic, renal, or cardiac function and concomitant disease or other therapy.
 
Children
 
There are established efficacy and safety in children ademetionin.
 
Hepatic Impairment
 
There is no difference in healthy subjects and patients with chronic liver disease are similar.
 
Renal impairment
 
Not been studied in patients with renal impairment. For this reason it is recommended
application of the product with caution.
 
If you take more than the dose Transmetil
 
No evidence of an overdose of this medicine.
 
If you miss a dose Transmetil
 
Take the missed dose as soon as you remember and then go to the normal mode of treatment. If it is almost time for your next dose, skip the missed. Do not take a double dose to make up for a forgotten tablet.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
 

 POSSIBLE SIDE EFFECTS

 
As with all medicines, when taking Ademetionin may occur side effects. That table includes reactions observed in clinical trials of the product.
 
 Adverse reaction classifications
 
Infections and infestations
Urinary tract infections
 
Psychiatric Disorders
 
Confusion
Insomnia
Nervous Syste
Dizziness
Headache 
Chills
Cardiac disorders
Cardiovascular disorders
Vascular Disorders
Hot flashes
uperficial phlebitis
Gastrointestinal Disorders
Distension of the bowel
Abdominal pain
Diarrhea
Acids
Inflammation of the lining of the esophagus
Intestinal gas
Pain 
Bleeding from the gastrointestinal tract 
Nausea 
Vomiting
Hepatobiliary disorders
Biliary colic 
Liver cirrhosis
 
Skin and subcutaneous tissue disorders
 
Skin changes (increased sweating
Persistent itching
 
Skin reactions
 
 
Musculo-skeletal, and connective tissue disorders
 
Joint pain
Muscle spasm
 
General disorders and administration site conditions
Slimming 
Chill
Influenza-like illnes
Peripheral ede 
Fever
Discomfort
  
Effects observed after the release of the product:
 
Immune system disorders - severe allergic reaction which causes difficulty in breathing or dizziness (anaphylactic reaction).
 
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
 

 HOW TO STORE TRANSMETIL

 Keep out of reach of children.
 This medicine should not be sahranva above 25 ° C.
 Transmetil should not be used after the expiry date stated on the pack. The expiry date refers to the last day of that month.
 
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
 

 ADDITIONAL INFORMATION

 
What Transmetil
 The active substance is ademetionin. Each gastro-resistant tablet contains 949 mg ademetionin (ademetionine), which corresponds to 500 mg of ionic substance.
 The other ingredients are: microcrystalline cellulose, magnesium stearate, polyethylene glycol 6000, political takrilati, polysorbates, silica, silicone emulsifiers, sodium starch glycolate.
 
Transmetil looks like and contents of pack
 
Gastro-resistant tablets are white.
Each box contains 1 blister (aluminum / aluminum) with 10 gastro-resistant tablets.
€ 28.00
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