TORVACARD. 20 mg. 30 tablets
TORVACARD. 20 mg. 30 tablets
Atorvastatin lowers cholesterol, LDL-xolesterola, apolipoproteinV and triglycerides in the blood plazma.V same time it helps to increase HDL cholesterol and apolipotrotein A.
This product is intended for treating:
- Elevated cholesterol levels in the blood (primary hypercholesterolaemia) or increased blood levels of both cholesterol and triglycerides (mixed hyperlipidaemia, corresponding to type IIa or IIb in rankings Fredriksson);
- Inherited elevated levels of blood cholesterol in familial hypercholesterolemia (heterozygous form) in the case of other methods (such as. Modification of diet, exercise, weight reduction) are not sufficiently effective or
- Heritable elevated cholesterol levels in familial hypercholesterolemia (homozygous form) in conjunction with other therapeutic methods for reducing fat in blood (e.g., LDL apheresis) or if some of these therapeutic methods are not available.
When should avoid drinking Torvakard?
Torvakard should not be used in the case where:
- You are allergic to any component of the product;
- You suffer from liver disease or unexplained persistent elevations of hepatic enzymes (serum transaminases) in the blood;
- You suffer from a disease of skeletal muscle;
- You are pregnant or planning to become pregnant in the near future;
- You are breast-feeding;
- You are a woman of childbearing age and are taking certain contraceptives.
Experience with the use of atorvastatin in children is limited. Therefore, it can only be prescribed by a specialist.
In which cases Torvakard can be used only after the explicit consent of a doctor?
Below are described situations in which you must use Torvakard only if absolutely necessary and with caution. Please consult your doctor. This also applies to past situations.
Atorvastatin, the active ingredient in Torvakard should be used with caution in patients who consume substantial quantities of alcohol and / or having a history of liver disease minaloto.Ako your doctor has told you have an intolerance to some sugars, talk to him before taking this medicine.
Please consult your doctor if you are simultaneously taking other drugs (see Drug Interactions).
What should be considered for elderly patients.
In patients over 70 years of safety and tolerability in implementing recommend to a dose comparable to those of other patients
What should your doctor for the period before your illness?
• Have you had kidney disease?
• Has reduced thyroid function?
• Is there a hereditary muscle diseases in your family?
• Have you had liver disease and / or if you drink large amounts of alcohol?
• Have you had toxic to muscle damage when treated with hypolipidemic agents?
What you should tell your doctor during treatment with Torvakard?
• Muscle pain, cramps, or weakness, particularly if accompanied by malaise and fever;
• All medicines prescribed by another physician for treatment of other diseases / problems;
• Any changes in your health.
Which medicines affect performance and operation of Torvakard which medicines may be affected by Torvakard?
It is the reaction of such medicinal products from this therapy group (inhibitor of HMG-CoA reductase) to that suppress the body's immune response (e.g., cyclosporine), other drugs for reducing the levels of fat in the blood (fibrates, nicotinic acid ), macrolide antibiotics including erythromycin and some antifungals (antifungal azoles). This mutual influence of drug action can be expressed in turn, regardless of other effects on muscle pain and increases in muscle enzymes (CK) rarely even in the degradation of muscle cells (rambdomioliza) renal nedostatachnost.Tezi medicines and macrolide antibiotics may be administered simultaneously with Torvakard by detailed instructions from your application lekar.Ednovremennoto colestipol and atorvastatin resulted in amplification of the effect of lowering the level of fat in the use kravta.Ednovremennata atorvastatin digoxin and the concomitant use of atorvastatin and certain medicines prevent pregnancy (contraceptives containing norethisterone and ethinyl estradiol) resulted in a moderate increase in the concentration of these products in the blood. This fact should be borne in mind when your doctor determines the dose of the aforementioned drugs produkti.Ednovremennoto administration of drugs that decrease stomach acidity (antacids containing magnesium or aluminum) reduces the concentration of atorvastatin in the blood without reducing effect lowering of cholesterol in the blood. Simultaneous use of erythromycin increases the concentration of atorvastatin in the blood.
The concomitant use of warfarin and Torvakard (product delay blood clotting), your doctor must often carry out check-ups, especially at the beginning of clinical studies lechenieto.Pri no interactions were observed during co-administration of atorvastatin and cimetidine (tool lowering the acidity of the stomach) or phenoxazin (pain relieving medicine). sure that this information also applies to medicinal products which are used immediately before the commencement of treatment with atorvastatin.
Dosage and method of administration
If your doctor advises otherwise, adhere to the following recommendations for use of Torvakard. Please follow these instructions carefully, as otherwise it is possible to reduce the effectiveness of Torvakard.
How often and how much should I take Torvakard?
Your doctor will advise you to follow cholesterol-lowering diet, and you should follow this diet also throughout Torvakard.Lechenieto therapy should begin with 10 mg atorvastatin daily. In this dosage form is currently available Torvakard 10 tablets. Further, the dosage will be adjusted by the doctor so as to achieve the recommended levels of LDL-cholesterol. Dosage adjustment should be made at intervals of 4 weeks or more. The maximum daily dose is 80 mg of atorvastatin.
• Increased levels of cholesterol (hypercholesterolemia) or cholesterol and triglshteridi together (mixed hyperlipidaemia)
The majority of patients respond well to a 10-mg atorvastatin tablets (i.e. 1 tablet Torvakard 10). As a rule, the therapeutic effect is achieved within 2 weeks and maximal therapeutic effect is reached after 4 weeks. This effect is maintained with continued treatment.
• inherited high cholesterol (familial hypercholesterolaemia)
- Heterozygous familial hypercholesterolemia
The starting dose is 10 mg atorvastatin daily. The dosage may be individualized by the clinician to 40 mg of atorvastatin per day at intervals of 4 weeks. Subsequently, the physician may combine the atorvastatin with an ion-exchange resin with bile acids added or atorvastatin dosage can be increased to 80 mg per day.
- Homozygous familial hypercholesterolemia
In clinical trials mean reduction in LDL cholesterol is about 21%. In these studies atorvastatin was administered at doses up to 80 mg daily.
The dosage of Torvakard in patients with homozygous familial hypercholesterolemia is 10-80 mg daily. Torvakard must be administered concomitantly with other therapeutic methods for lowering cholesterol (LDL apheresis) or, when these therapies are not available.
Experience in the treatment of homozygous familial hirepholesterolemiya in children is only a small number of pediatric patients (aged 4 to 17 years. Treatment of children should only be carried out by a specialist. Torvakard recommended starting dose for these patients is 10 mg daily. Could be increased to 80 mg daily, depending on response and tolerability. no data on the effect of this treatment on the development of children.
• Dosage in patients with impaired renal function and elderly patients elderly need a special dosage adjustment in these patients as kidney disease do not affect the treatment Torvakard.
In clinical studies it has been found that the particular adjustment of the dosage to patients in the elderly are also not necessary.
Method of administration
How and when should you take Torvakard?
Torvakard can be taken with a little liquid at any time of day without regard to food.
How long should I use Torvakard?
Torvakard is designed for continuous use.
What to do when he accepted a lower dose or Torvakard one dose is missed?
Do not double the dose, proceed according to the adopted scheme.
What to do if you experience muscle pain, feeling of weakness and fever?
Seek medical advice immediately and consult on the further use of Torvakard.
Overdose: What to do if you take too many tablets Torvakard (intentional or accidental overdose)?
No specific treatment of overdosage with atorvastatin. In case of overdose, get medical help.
Like other medicines Torvakard can have adverse reaktsii.Torvakard generally well tolerated. Adverse reactions were usually mild and transient.
The following adverse reactions have been described by patients using atorvastatin (the active ingredient contained in Torvakard) with a frequency of occurrence greater than 1%: nausea, constipation, flatulence, indigestion, abdominal pain, diarrhea, pain in muscles or joints v_garba pain, tingling sensation (tingling), edema, feeling of weakness, headache, dizziness and insomnia.
In patients taking medicinal products containing a drug atorvastatin was observed, like other drugs of this group, increased liver enzymes, which is usually mild and transient and did not require discontinuation of treatment.
Moreover, sometimes it is reported that the level of another enzyme - creatine phosphokinase (CK). In rare cases, this increase is associated with muscle pain, tenderness or weakness of the muscles. If you notice any unusual muscle pain, muscle cramps, or feeling faint, please tell your doctor as soon as possible.
Rarely experienced other side effects, but a direct connection with the administration of atorvastatin was not always proven: muscle inflammation (myositis), muscle disorders (myopathy, rhabdomyolysis), non-inflammatory diseases of the nerves (peripheral neuropathy), inflammation of the pancreas inflammation of the liver, jaundice, vomiting, decreased appetite, or vice versa, weight gain, impotence, increased or decreased blood sugar, chest pain, decreased platelet count (thrombocytopenia), hair loss and memory impairment. Allergic reactions have been reported in susceptible individuals, especially skin rashes, hives and itching. Rarely can be severe allergic reactions. If you develop an allergic reaction with swelling or shortness of breath or skin reaction affecting extensive area, seek medical pomosht.V case of possible side effects as quickly as possible, tell your doctor who will decide what should be napravi.Ako notice any side effects that is not described in this information leaflet, please tell your doctor or pharmacist.
No special storage requirements.
Shelf life: 2 years