TAVANIC 500 mg. 5 tablets

TAVANIC 500 mg. 5 tablets
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What is Tavanic tablets and what is it used?

The name of your medicine is Tavanic tablets. Tavanic tablet comprising a drug called levofloxacin. It belongs to a group of medicines called antibiotics. Levofloxacin is a quinolone antibiotic. It works by killing bacteria that cause infections in your body.

Tavanic tablets may be used to treat infections of:

• Sinus
• Veli lungs, in people with long-term breathing problems or pneumonia
• Urinary tract infections, including kidney or bladder
• The prostate gland, if you have prolonged infection
• The skin and underlying tissues, including muscle. Sometimes referred to as soft tissue '.

In some special cases, Tavanic tablets can be used to reduce the likelihood of lung disease called anthrax or worsening of the disease after being exposed to the bacterium that causes anthrax.

2. What you need to know before taking Tavanic tablets?

DO NOT take this medicine and inform our doctor if:

• you are allergic to levofloxacin, any other quinolone antibiotic such as moxifloxacin, ciprofloxacin or ofloxacin or any of the other ingredients of this medicine (listed in section 6 below)
Signs of an allergic reaction include: rash, difficulty in swallowing and breathing, swelling of the lips, face, throat or tongue
• have ever had epilepsy
• you have ever had problems with tendons as tendinitis, which were related to treatment with quinolone antibiotic. Tendon is the link that connects your muscles to the skeleton
• you are a child or adolescent
• are pregnant, may become pregnant or think you may be pregnant
• breast-feeding

Do not take this medicine if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist before taking Tavanic tablets.

Warnings and Precautions

Talk to your doctor or pharmacist before taking your medicine if:

• If you are 60 or more years
• using corticosteroids, sometimes called steroids (see section: Other medicines and Tavanic ")
• you have ever had a seizure (convulsion)
• have brain damage due to stroke or other brain injury
• you have kidney problems
• have a condition known as "glucose-6-phosphate dehydrogenase deficiency." More likely to have serious problems with blood when taking this medicine
• have ever had mental problems
• you have ever had heart problems, it is necessary caution when using this type of medication, if you were born with or have a family history of prolonged QT interval (seen on ECG, electrical recording of the heart), you have an imbalance of salts in the blood (especially low levels of potassium or magnesium in the blood), have a very slow heart rhythm (called bradycardia), have a weak heart (heart failure), have had a heart attack (myocardial infarction), or woman you are elderly, or are taking other medicines which lead to ECG changes (see section,, Other medicines and Tavanic ").
• have diabetes
• you have ever had liver problems
• have myasthenia gravis

If you are not sure that any of these apply to you, talk to your doctor or pharmacist before taking Tavanic tablets.

Other medicines and Tavanic

Talk to your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Because Tavanic tablets can affect the way other medicines work. Also some medicines can affect the operation of Tavanic tablets.

In particular, talk to your doctor if you are taking any of the following drugs: as this will increase the possibility of adverse effects when taking Tavanic:

• Corticosteroids, sometimes called steroids used in inflammation. May be more likely to get the inflammation and / or rupture of tendons.
Warfarin - used to thin the blood. More likely to have bleeding. It may be necessary for your doctor to do regular blood tests to check your blood clotting.

Theophylline - used in breathing problems. More likely to get fit (seizure) if taken with Tavanic.

Non-steroidal anti-inflammatory drugs (NSAIDs) - used for pain and inflammation such as aspirin, ibuprofen, fenbufen, ketoprofen and indometatsii. More likely to receive seizure (convulsions) if you take them with Tavanic tablets. Cyclosporin - used after organ transplantation. More likely to get side effects of cyclosporine.

Drugs with known effect on cardiac rhythm. These include medicines used in abnormal heart rhythms (such as quinidine antiarigmitsi, hydroquinidine, disopyramide, sotalol, dofetilide, ibutilide and amiodarone), for depression (tricyclic antidepressants such as amitriptyline and imipramine) for mental illness (antipsychotics) and bacterial infections (macrolide antibiotics such as erythromycin, azithromycin and clarithromycin)

• Probenecid - used for gout and cimetidine - used in ulcer and heartburn. Particular caution is required when taking any of these medicines with Tavanic. If you have kidney problems. Your doctor may prescribe a lower dose.

Do not take Tavanic tablets at the same time with the following medicines as they may affect the way Tavanic tablets:

• Tablets containing iron (anemia), dietary supplements containing zinc, antacids containing magnesium or aluminum (with acids or burning sensation), didanosine or sucralfate (ulcers of the stomach). See section 3 "If you take a tablet containing iron supplements containing zinc, antacids, sucralfate or didanosine" below.

Urine test for opiates

Urine tests may show false positive results for strong painkillers called opioids in people taking Tavanic tablets. If your doctor has scheduled urine test, tell him that you are taking Tavanic tablets.

Tests for tuberculosis

This medicine may cause false negative results in some tests used in laboratories to search for bacteria causing tuberculosis.

Pregnancy and lactation

Do not take this medicine if:
• are pregnant will become pregnant or think you may be pregnant
• breast-feeding or planning to breast-feed

Driving and using machines

You may get side effects after taking this medicine, including feeling of dizziness, drowsiness, dizziness (vertigo) or changes in vision. Some of these side effects can affect your ability to concentrate and speed of reaction. If this happens, do not drive or do work that requires caution.

3. How to take Tavanic tablets?

Always take this medicine exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist.

Taking the medicine

• Take this medicine by mouth
• Swallow the tablet whole with water
• The tablets may be taken during meals or at any time between meals Protect your skin from sunlight

Protect from direct sunlight while taking this medicine and 2 days after you stop taking it. This is because your skin will be more sensitive to the sun and can be red, burn or get a severe rash with blisters if not, take the following precautions:

• Use a sunscreen with a high SPF.
• Always wear a hat and clothes that cover your arms and legs.
• Avoid exposure to the sun

If you are already taking tablets containing iron supplements containing zinc, antacids, sucralfate or didanosine
• Do not take these medicines at the same time as Tavanic. Take your dose determined from these drugs at least 2 hours before or after Tavanic tablets.

How many tablets to take

• Your doctor will decide how many Tavanic tablets you should take.
• The dose depends on the type of infection you have and where in your body's infection.
• The duration of treatment depends on the severity of your infection.
• If you feel that the effect of the medicine is too weak or strong, do not change the dose yourself, ask your doctor.

Adults and the elderly
Sinus Infection

• Two tablets Tavanic 250 mg, once daily
• or a tablet Tavanic 500 mg, once daily

Lung infection in individuals with prolonged breathing problems

• Two tablets Tavanic 250 mg, once daily
• or a tablet Tavanic 500 mg, once daily


• Two tablets Tavanic 250 mg, once or twice daily
• or a tablet Tavanic 500 mg, once or twice daily

Infection of the urinary tract including the kidneys or bladder

• One or two tablets of Tavanic 250 mg, per day
• or 1/2, or one tablet Tavanic 500 mg, per day

Infection of the prostate gland

• Two Tavanic tablets 250 mg once daily
• or a tablet Tavanic 500 mg, once daily

Infection of the skin and underlying tissues including muscles

• Two Tavanic tablets 250 mg once or twice daily
• or one tablet Tavanic 500 mg, once or twice a day

Adults and the elderly with kidney problems

You may need your doctor give you a lower dose.

Children and adolescents

This medicine should not be given to children or teenagers. If you take more Tavanic tablets than necessary

If you take more tablets than you should, contact your doctor or get other medical advice immediately. Take the medicine pack with you. This is necessary to enable a doctor to know what you have taken. May occur following effects: convulsive seizures, confusion, dizziness, decreased consciousness, presence of tremors and heart problems - leading to irregular heart beat, also sick (nausea) or presence of acids.

If you forget to take Tavanic tablets

If you forget to take a dose, take it as soon as possible after you remember, unless it is too close to the time for your next dose. Do not double the next dose to make up for a missed dose.

If you stop taking Tavanic tablets

Do not stop taking Tavanic, just because you feel better. It is important to complete the course of treatment with tablets that prescribed by your doctor. If you stop taking the tablets too soon, the infection may return, your condition worsen or bacteria to become resistant to the drug.

If you have further questions about this medicine, ask your doctor or pharmacist.

4. Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them. These reactions are usually mild or moderate and often disappear after a short time.

Stop taking Tavanic and see a doctor or go to a hospital immediately if you notice the following side effects:

Very rare (may affect up to 1 in 10,000 people)

• You have an allergic reaction. Signs may include: rash, difficulty swallowing or breathing, swelling of the lips, face, throat or tongue

Stop taking Tavanic and see a doctor immediately if you notice any of the following serious side effects - you may need urgent medical treatment:

Rare (may affect up to 1 in 1000 people)

• Watery diarrhea that may contain blood, sometimes with abdominal cramps, and fever. These may be signs of a severe bowel problem

• Pain and inflammation of the tendons or ligaments, which may lead to rupture. Most frequently involves the Achilles tendon.

• Seizures (convulsions)

Very rare (may affect up to 1 in 10,000 people)

• Burning, tingling or pain. This may indicate a condition called neuropathy


• Severe skin rashes which may include blistering or peeling of the skin around the lips, eyes, mouth, nose and genitals

• Loss of appetite, yellowing of skin and eyes, dark urine, itching, or heaviness in the stomach (abdomen). These may be signs of liver problems, which can include fatal liver failure.

If your eyesight becomes impaired or if you have any other problems with your eyes while taking Tavanic, consult an eye specialist.

Tell your doctor if any of these side effects become severe or last more than a few days:

Common (may affect up to 1 in 10 people)

»Sleep problems

• Headache, dizziness
• Feeling sick (nausea, vomiting) and diarrhea
• Increased levels of certain liver enzymes in the blood

Uncommon (may affect up to 1 in 100 people)

• Changes in the number of other bacteria or fungi, infections caused by fungi called Candida, which may require treatment
• Change in number of white blood cells, which can be seen in the results of some blood tests (leucopenia, eosinophilia)
• Anxiety (restlessness), confusion, nervousness, somnolence, tremor, dizziness (vertigo)
• Shortness of breath (dyspnea)
• Changes in taste, loss of appetite, upset stomach or indigestion (dyspepsia), pain in the stomach area, feeling bloated (flatulence) or constipation
• Itching and skin rash, severe itching or hives (urticaria), excessive sweating (hyperhidrosis)
• Joint pain or muscle pain
• Blood tests may show unusual results due to liver (elevated bilirubin) or renal (creatinine increase) problems
• General weakness

Rare (may affect up to 1 in 1,000 people)

• Easier bruising and bleeding due to low platelet count (thrombocytopenia)
• Reduced number of white blood cells (neutropenia)
• Excessive immune response (hypersensitivity)
• Decreased levels of blood sugar (hypoglycemia). This is important for people with diabetes.
• Seeing or hearing things (hallucinations, paranoia), changes in opinion and thoughts (psychotic reactions) with the risk of suicidal thoughts or actions
• Feelings of depression, mental health problems, anxiety (agitation), vivid dreams or nightmares
• Numbness of the hands and feet (paresthesia)
• Problems with hearing (tinnitus) or vision (blurred vision)
• Unusually rapid heart beat (tachycardia) or low blood pressure (hypotension)
• Muscle weakness. This is important for people with myasthenia gravis (a rare disease of the nervous system).
• Changes in the operation of the kidney and rarely renal failure, which may be due to an allergic renal reaction called interstitial nephritis,
• Fever

Other side effects include:

• Reduced number of red blood cells (anemia), this can make the skin pale or yellow due to damage of red blood cells; low number of all types of blood cells (pancytopenia)
• Fever, sore throat and malaise, which does not pass away. This may be due to a reduced number of white blood cells (agranulocytosis).
• Sharp violation of blood circulation (shock similar to anaphylaxis)
• Increases in blood sugar (hyperglycemia) or low blood sugar leading to coma (hypoglycemic coma). This is important for people with diabetes.
• Changes in smell, loss of sense of smell or taste (parosmia, anoemnya, ageusia)
• Difficulty walking or movement (dyskinesia ekegrapiramidni disorders)
• Temporary loss of consciousness or fainting (syncope)
• Temporary loss of vision
• Violation or hearing loss
• Abnormal fast heart rhythm, life-threatening irregular heartbeat, including cardiac arrest, variation in heart rhythm (called QT prolongation, which can be seen on ECG, electrical activity of the heart)
• Difficulty breathing or wheezing (bronchospasm)
• Allergic lung reactions
• Pancreatitis
• Inflammation of the liver (hepatitis)
• Increased skin sensitivity to sunlight or UV light (photosensitivity)
• Inflammation of the vessels that carry blood throughout the body due to an allergic reaction (vasculitis)
• Inflammation of the tissues in the mouth (stomatitis)
• Rupture or destruction of muscle (rabdomnoliza)
• Redness and swelling of the joints (arthritis)
• Pain, including pain in the back, chest or limbs
• Attacks of porphyria in people who already have porphyria (a very rare metabolic disease)
• Prolonged headache with or without blurred vision (benign nitrakranialna hypertension)

If you get any side effects, tell your doctor or pharmacist.

This includes any possible effects not listed in this leaflet.

5. How to store Tavanic tablets?

Keep out of the reach and sight of children.

This medicine does not require any special storage conditions, but it is best to keep Tavanic tablets in the original blister packs and boxes in a dry place.

Do not use this medicine after the expiry date (EXP) which is stated on the blister and carton after "EXP". The expiry date refers to the last day of that month.

Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information
What Tavanic tablets contain?

The active substance is levofloxacin. Each tablet Tavanic 500 mg tablets contains 500 mg of levofloxacin.

Other ingredients are:

• For the tablet core: crospovidone, hypromellose, microcrystalline cellulose and sodium stsarilfumarat

• For the tablet coating: hpromeloza, titanium dioxide (E 171), talc, macrogol, iron oxide yellow E (172) and red iron oxide (EI72)
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