Sumamed table. 500 mg. 3 tablets
Sumamed table. 500 mg. 3 tablets
What Sumamed tablets 500 mg?
Antibacterials for systemic use. Macrolide antibiotic.
Antimicrobial activity and action
Azithromycin is the first azaliden antibiotic makrolidi.Azitromitsin a new class of broad spectrum of activity and is active against most strains of the following microorganisms:
Gram - positive bacteria: Streptococcus pneumonie, S. pyogenes, S. agalactiae, S.viridans, streptococcus group C, F and G and Staphylococcus aureus;
Gram - negative bacteria: Haemophilus influenzae, H. paramfluenzae, H. ducreyi, Moraxella catarrhalis, Bordetella pertussis, B. parapertussis, Legionella pneumophilia, Brucella melitensis, Helicobacter pylori, Campylobacter jejuni, Neisseria gonorrhoeae and Gardnerella vaginalis;
Anaerobic bacteria: Bacteroides bivius, Clostridium perfringens, and Peptostreptococcus species and Peptococcus;
Other organisms: Chlamydia trachomatis, C pneumoniae, Mycoplasma pneumoniae, Ureaplasma urealytium, Treponema pallidum and Borellia burgdorferi
Azithromycin is well absorbed after oral administration and rapidly passes from the serum into the tissues. It is widely distributed throughout the body and achieves high and sustained tissue concentrations. Azithromycin concentrates in phagocytes that migrate into the infected and thus increases the distribution of the drug in the infected tissues. Its half-life is prolonged, and the release of tissue is slow. The primary route of elimination is via the bile, urine excretion of azithromycin niska.Farmakokinetichnite properties provide a short and simple dosing regimen, once daily for 3 days.
What used Sumamed tablets 500 mg?
Sumamed tablets 500 mg is used to treat infections caused by susceptible organisms following:
infections of the upper respiratory tract bacterial pharyngitis / tonsillitis, sinusitis and otitis media;
infections of the lower respiratory tract bacterial bronchitis, acute exacerbation of chronic bronchitis, interstitial and alveolar pneumonia;
infections of skin and soft tissue infections: erythema chronicum migrans (I Lyme disease), erysipelas, impetigo and secondary pyoderma;
sexually transmitted diseases: uncomplicated urethritis / cervicitis;
gastric and duodenal infection caused by Helicobacter pylori.
In what cases should not take Sumamed tablets 500 mg?
Sumamed 500 mg tablets should not be used in case of hypersensitivity to macrolide antibiotics.
Special precautions for use
Pharmacokinetics of Sumamed 500 mg tablets provide short and simple dosing regimen. Not requiring an extended application of Sumamed 500 mg tablets in the above indication than recommended on the label.
What other drugs affect the action of Sumamed 500 mg tablets or are affected by it?
Antacids affect absorption rate Sumamed tablets 500 mg. It is recommended that an interval of at least 2 hours after administration of Sumamed tablets 500 mg and antacid lekarstvo.Pri patients receiving ergot alkaloids, ergotism can be increased by concomitant administration of some macrolide antibiotics, but no evidence of probable interaction between ergot derivatives and Sumamed tablets 500 mg. It is known that macrolide antibiotics interact with digoxin, cyclosporin, astemizole, triazolam, midazolam. Although no evidence of interaction between Sumamed tablets 500 mg and these products, it is advisable to concomitant use is strictly monitorirane.Pri concomitant use of your medicine and warfarin, or oral anticoagulants may experience increased bleeding tendency. Tell your doctor about all the medicines you take, including those obtained without prescription.
Should be exercised when administering Sumamed ® tablets 500 mg in patients with impaired hepatic function.
What should I keep in mind during pregnancy and lactation?
Reproduction studies in animals have not shown adverse effects on the fetus. Because animal studies are not always predictive of human response, Sumamed 500 mg tablets should be used during pregnancy and lactation only if strictly necessary
Dosage, method and duration of administration
In what quantity and how often you should take Sumamed tablets 500mg?
Sumamed 500 mg tablets should be taken once a day at least one hour before or two hours after meals.
Upper and lower respiratory tract and skin and soft tissue (with the exception of erythema migrans): 500 mg (one tablet of 500 mg as a single dose) for 3 days.
For all erythema migrans dosage is 3 g: 1 g (two tablets of 500 mg) once the first day, followed by 500 mg (one tablet of 500 mg) from the second to the fifth day as single daily doses.
STDs: 1 g (two tablets of 500 mg) once, only once.
Gastric and duodenal infection caused by Helicobacter pylori: 1 g as a single daily intake (two tablets of 500 mg) for 3 days in combination with amoxicillin 1 g twice daily for 7 days and omeprazole 20 mg twice daily for 7 dni.Ne require dose adjustment in the elderly.
Overdose and other errors in use
What should you do if you take more than Sumamed tablets 500 mg?
There are no data on overdose with Sumamed tablets 500 mg. Overdose with macrolide antibiotics may experience hearing loss, severe nausea, vomiting and diarrhea. In case you need to induce vomiting and immediately seek medical attention.
What should you do if you forget to take Sumamed tablets 500mg?
The missed dose should be taken as soon as possible, and the next - at intervals of 24 chasa.Ne take a double dose of medicine to make up the missed reception!
Sumamed 500 mg tablets rarely causes transient and mild side effects. Can occur (nausea, diarrhea, stomach pain, vomiting, and flatulence), and rash. You can Reversible elevations of liver enzymes. For a change, they return to normal two or three weeks after the lechenieto.Vazmozhni Hypersensitivity reactions such as rashes, hives or fotochuvstvitelnost.V rare cases of serious allergic (rarely fatal) reactions. Some of them are as a result of recurrence of symptoms, leading to an extension of the period of observation and lechenie.Mnogo rarely, reversible effects on the central nervous system, such as fatigue, headache, dizziness, smell and taste disturbance, tingling, nervousness and insomnia. Sometimes you can be pain in stavite.Ryadko reported irregular heartbeat (palpitations and arrhythmias including tachycardia). In instances of any side effects, including those that are not listed in this leaflet, please consult your doctor or pharmacist.
Special precautions for storage
Do not store above 25 ° C. Keep out of reach of children! Apply only on prescription!
Active substance: 1 coated tablet 500mg Sumamed tablets contain 500mg azithromycin dihydrate.
Tablet core: calcium hydrogen phosphate, hypromellose, maize starch, prezhelatinozno starch, microcrystalline cellulose, sodium lauryl sulfate, magnesium stearate.
Film coating: hypromellose, indigotine dye (E132), titanium dioxide (E171), polysorbate 80, talc.