SOLKOZHIN Fl. 0.5 ml

SOLKOZHIN Fl. 0.5 ml
€ 26.00
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Benign lesions of the cervix as:
     ectopic vaginal portion of the cervix (ectopia, eritroplakiya, psevdoerozii)
     area of transformation
     ovula Nabothi (after incisions)
     polyps and postoperative cervical granulomas (after hysterectomy).

SOLKOZHIN Fl. 0.5 ml


1 ml of solution contains:
Nitric acid 70% (Nitric acid 70%) 537,0 mg
Acetic acid, glacial (Acetic acid, glacial) 20,4 mg
Oxalic acid dihydrate (Oxalic acid dihydrate) 58,6 mg
Zinc nitrate hexahydrate (Zinc nitrate hexahydrate) 6,0 mg
For a full list of excipients, see section 6.1.


Vaginal Solution


 Therapeutic indications
Benign lesions of the cervix as:
 ectopic vaginal portion of the cervix (ectopia, eritroplakiya, psevdoerozii)
 area of transformation
 ovula Nabothi (after incisions)
 postoperative granulomas and polyps of the cervix (after hysterectomy).
 Posology and method of administration
Solkogin vaginal solution is designed for use on local surface
cervical and can be applied only by an obstetrician.
 Remove the cervical mucus with a cotton swab. Cervix by staining with 3% vinegar solution size of the cervical lesion is clearly visible.
 Treat lesion swab moistened with a solution of mild Solkogin clapping movements.
 After 1-2 minutes, repeat the procedure with a new cotton swab with Solkogin solution. Dual application has proven effective.
 After treatment, the patient can go home without any special instructions or restrictions for bathing, swimming, or sexual intercourse.
 In case of ectopia with deep fissures, which Solkogin solution can not penetrate well enough after the first treatment recommended examination and re-treatment after 4 to 6 days.
 Typically, the patient is re-examined 4 weeks after treatment. If by that time the lesion is not completely healed, requiring repeated application of Solkogin solution twice a checkup 4 weeks later.
Solkogin no relevant indication for use in children.
Malignant changes in vaginal part of cervix dysplasia and cellular hypersensitivity to the active substances.
 Special predupreyasdeniya and precautions for use
Avoid contact with the preparation of the external genitalia and vaginal mucosa. Solkogin solution should not be applied to the inflamed areas. In the event of the use of pain medication should be discontinued.
Attention! Improper use of Solkogin solution (eg, the use of too much) can cause damage to the mucosa and underlying tissues.
Solkogin solution contains acids. Care must be taken to avoid contact with clothes, skin and especially eyes. In case of misuse, the affected area should be immediately cleaned with a wet cotton swab. If the solution gets into your eyes, you should immediately rinse with plenty of water or diluted basis, such as 1% sodium bicarbonate solution ..
 Interaction with other medicinal products and other forms of interaction
No interaction studies.
 Pregnancy and lactation
Solkogin treatment during pregnancy must be avoided: No data on the use of Solkogin on animals or in pregnant women. The potential risk for humans is unknown.
 Effects on ability to drive and use machines
Solkogin not affect your ability to drive and use machines as a topical application.
Based on MedDRA convention, adverse reactions are classified as follows:
Very common (> 1/10)
Common (> 1/100 to <1/10)
Uncommon (> 1/1, 000 to <1/100)
Rare (> 1/10, 000 to <1/1, 000)
Very rare (<1/10000), not known (data can not be estimated)
The following adverse events, information on the frequency.
 In case of improper conduct treatment, such as accidental contact with the vagina or external genitalia may appear burning and itching.
 In case of improper use (when used too much) underlying tissue can be damaged.
When using a larger amount of the drug can occur burning and itching (see 4.8).

 Pharmacological Properties

 Pharmacodynamic properties
Pharmacotherapeutic group: organic acids, ATC code: G02CX 00
As a result of their specific composition, solution Solkogin affect various epithelial tissues of the cervix. When the drug is in contact with the surface and transformed ectopic cervical observed immediate devitalization and fixing in vivo ectopic tubular epithelium and subepithelial stroma (if erozio). Multilayered squamous epithelium Porcius and vagina, which is more resistant, virtually unaffected. Devitalization it for a few minutes and can be recognized by clear yellow, or gray staining of tissues. The reaction is acid burning in the literal sense, as devitalized tissue remains in place and forms a protective coating that dropped a few days due to idiopathic reepitelizatsiyata with squamous epithelium.
 Pharmacokinetic properties
Pharmacokinetics of Solkogin solution were investigated. It acts locally. Acid and nitrogen ions reducing products contained in Solkogin solution leads to rapid pathological devitalization and tissue fixation. Absorption during this process seems insignificant, given the small amount of administered drug can be expected systemic action.
 Preclinical safety data
Preclinical data reveal no special hazard for humans based on conventional studies of safety pharmacology, repeated dose toxicity, genotoxicity, carcinogenicity, and reproductive toxicity.
Single dose toxicity:
There were no toxic signs or symptoms in rabbits treated once on the vaginal mucosa. Beyond the expected mild to moderate irritation or corrosive effects were not established other local effects on the vulva.
Double dose toxicity:
There were no systemic effects in rabbits treated three times at intervals of 10 days in the vaginal mucosa. Mild to moderate irritation, including erythema, edema and ulceration of the outer part of the vagina were observed. Repeated administration resulted in a well-marked degree of inflammation in chronic ulceration and scarring with subsequent constrictive changes of the vagina.
When properly used, it can be considered safe. Moreover, the amount of absorbed substances for topical application is minimal.


 List of excipients
Purified water.
 Shelf Life
3 years
 Special precautions for storage
Do not store above 25 ° C.
Solkogin solution is highly caustic (corrosive) and should be stored out of reach of children.
Do not use after the expiration date printed on the package. The crystals, which are formed during the transport of the product at low temperatures disappear after a short warm-up (1-2 minutes) of the vial to 40 ° C (
 Nature and contents of container
Clear glass vial with a nominal volume of 2 ml; rubber stopper with aluminum cap. Contains 0,5 ml of solution.

€ 26.00
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