SIOFOR. 850 mg. 30 tablets

SIOFOR. 850 mg. 30 tablets
€ 15.00
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Siofor 850 is a medicament for the treatment of non-insulin-dependent diabetes mellitus in adults (type 2 diabetes). 

SIOFOR. 850 mg. 30 tablets

 
 
What is in your medicine?
drug
One tablet contains 850 mg metformin hydrochloride.
Excipients
Hypromellose, povidone, magnesium stearate , macrogol 6000, titanium dioxide ( E171 ) .
 
package
Siofor 850 in packs of 30, 60 or 120 tablets.
 
 
How does Siofor 850
Siofor 850 is a medicament for the treatment of non-insulin - dependent diabetes mellitus in adults ( type 2 diabetes ) .
 
 
What cures Siofor 850
Siofor 850 is a medicament for the reduction of high blood sugar levels in adult patients with diabetes ( type 2 diabetes mellitus in adults) ; particularly beneficial effect was observed in patients with obesity in which dieting alone or with a physical activity may not achieve adequate control of blood sugar. Siofor 850 can be used alone ( monotherapy) or in combination with other drugs , blood glucose lowering , or with insulin .
After failure of diet in patients with obesity and diabetes ( type 2 diabetes ), treatment with metformin as first- choice have been shown to decrease complications associated with diabetes .
 
 
When not to apply Siofor 850 ?
You should not use Siofor 850 in the following cases :
• Hypersensitivity to metformin hydrochloride or to any of the excipients of Siofor 850 ;
• increased acidity of the blood in diabetes (diabetic ketoacidosis ) , a condition preceding the coma ( coma ) ;
• renal failure or renal dysfunction (renal failure with elevated levels of creatinine in the blood) ;
• acute conditions that lead to impaired renal function , for example:
- Fluid loss during prolonged vomiting or severe diarrhea ( dehydration) ;
- Severe infections ;
- Circulatory failure ( shock) ;
• before, during and 48 hours after studies with intravascular administration of iodinated contrast media ;
• acute or chronic disease that may lead to a shortage of oxygen in the tissue ( tissue hypoxia ) , such as :
- Heart failure or pulmonary function ( respiratory failure) ;
- A recent myocardial infarction;
- Circulatory failure ( shock) ;
• hepatic dysfunction , acute alcohol intoxication , alcoholism ;
• breastfeeding.
 
What you should know before you start treatment with Siofor 850 ?
The risk of excessive accumulation of the drug and increased acidity of the blood lactate ( lactic acidosis) is mainly determined by renal function. Therefore preliminary determination of normal renal function is indispensable for the initiation of treatment with Siofor 850 .
Therefore, the evaluation of kidney function by determining the levels of serum creatinine should be repeated at intervals of at least once a year, even more often. If serum creatinine is the upper limit of normal, the assessment should be done at least two to four times a year. It should be noted that it is not always the levels of serum creatinine are significant, particularly in the elderly . Then evaluation of renal function prior to the start of treatment is required to measure other indicator - the clearance of creatinine .
Particular care is required in conditions which can be expected to change in renal function (e.g., at the beginning of the administration of certain drugs to treat high blood pressure or of rheumatic diseases ) .
Particular attention is required and impaired liver function.
In studies with intravascular administration of iodinated contrast media are at risk of acute renal failure. Therefore, you should discontinue Siofor ® 850 before this study. Treatment may be resumed two days after the survey , and only once the normal renal function.
If you are scheduled for surgery with general anesthesia , the use of Siofor ® 850 should be stopped two days before the operation. Treatment may be resumed two days after surgery and only after ascertaining normal renal function.
Tell your doctor if you are suffering from a bacterial or viral infection ( eg influenza , respiratory tract infection , urinary tract infections ) .
During treatment with 850 Siofor keep dieting and pay particular attention to the distribution of carbohydrate intake during the day . If you are overweight , you should continue to follow the diet to reduce weight under medical supervision.
Ingestion of large amounts of alcohol , the risk of hypoglycemia and lactic acidosis. Therefore, during treatment with Siofor ® 850 should avoid alcohol .
 
 
special warnings
In the event of undue accumulation , metformin can cause or facilitate the occurrence of lactic acidosis - a complication which, if left untreated, can lead to life-threatening condition (eg coma) . Cause of lactic acidosis can not only be an overdose , but the failure of contraindications . Therefore contraindications must be strictly adhered to (see "When should not apply Siofor ® 850 ?") .
Symptoms of lactic acidosis may starting to look like the side effects of metformin on the gastrointestinal tract : nausea , vomiting , diarrhea, abdominal pain. Within a few hours can manifest the full clinical picture with muscle pain and cramps, deep breathing noisy and blurred consciousness to coma. This requires immediate treatment in a hospital setting .
 
 
What interactions occur between Siofor 850 and other medicines you are taking ?
Please tell your doctor or pharmacist if you are currently taking other medicines or have recently applied other medicines , even if without a prescription.
During prolonged treatment with Siofor 850 , the initiation of a new treatment , and discontinuation of other medicines may affect blood sugar levels .
Please tell your doctor or pharmacist if you are currently or have recently taken the following medications ; corticosteroids, certain medicines for NZ high blood pressure ( ACE inhibitors) , drugs that increase urine output ( diuretics) , certain drugs for the treatment of bronchial asthma ( beta- sympathomimetics) , iodinated contrast media and medications containing alcohol .
 
 
During the administration of 850 Siofor should avoid foods and drinks containing alcohol.
Can not be used in children Siofor 850 ?
Due to lack of experience Siofor 850 should not be used in children.
 
 
Can be used Siofor 850 in elderly patients ?
Since the elderly often observed renal impairment , the dose of 850 Siofor tryavba be determined according to renal function. Therefore , renal function should be monitored regularly by your doctor.
 
Can be used Siofor 850 during pregnancy and lactation ?
pregnancy
Patients with diabetes who are pregnant , or planning a pregnancy , should not take Siofo / f 850 . In this case, to achieve a normal blood sugar levels need to take insulin . Therefore timely notify your doctor so he can change your treatment of insulin.
 
breastfeeding
You should not use this medication during breastfeeding .
 
 
Affect you Siofor 850 ability to drive and use machines ?
Treatment with Siofor 850 itself does not lead to excessive blood sugar ( hypoglycemia) and therefore has no effect on ability to drive and use machines. Combination therapy with insulin or other medicines that lower blood sugar can lead to excessive blood sugar ( hypoglycemia) and impair your ability to drive and use machines or work without safe support.
 
 
How and how much time should be used Siofor ® 850 ?
Apply Siofor 850 always as prescribed by your doctor. Please consult your doctor or pharmacist if you are not completely sure.
The dosage of Siofor 850 is determined by the physician and is individual for each patient , depending on the blood glucose levels and visited regularly by a physician.
 
 
Dosage instructions
Unless otherwise prescribed by your doctor , the usual starting dose is two to three tablets Siofor 850 per day (equivalent to 1700 mg to 2550 mg metformin hydrochloride), which is taken during or after meals. The maximum daily dose of three tablets per day Siofor 850 (equivalent to 2550 mg metformin hydrochloride).
The tablet was swallowed whole , during or after eating a sufficient quantity of liquid .
With the use of two or more tablets taken them to be distributed throughout the day , eg . one tablet each after breakfast and dinner.
Please consult your doctor if you feel that the effect of Siofor0 850 is too strong or weak.
 
 
What should I do in case of overdose with Siofor 850 ?
Please tell your doctor if you take a larger dose than usual Siofor 850 . Overdose with SioforR 850 does not lead to excessive blood sugar ( hypoglycemia) , but may increase the risk of lactic acidosis (see " Special warnings " ) .
 
 
What should I do in case of missing intake Siofor ® 850 ?
If you forget to take Siofor 850, take your normal dose on the next intake and try to follow the prescription for the future. In any case after ingestion miss compensate by taking more tablets .
 
 
What can be expected when discontinuing treatment with Siofor 850 ?
If self discontinue Siofor 850 without telling your doctor , you can expect an uncontrolled increase in blood glucose levels . This will in time lead to the onset of late diabetic complications , eye damage , kidney and vessels.
 
 
What side effects may cause Siofor 850 ?
As with all medications , Siofor 850 may lead to adverse reactions.
The incidence of adverse events is estimated as follows:
Very often more than 1 in 10 patients treated
Often in less than 1 in 10 but more than 1 in 100 patients treated
Nechesgi in less than 1 in 100 , but more than 1 per 1000 patients treated
Rare in less than 1 in 1,000 , but more than 1 out of 10,000 patients treated
Very rare in less than 1 in 10,000 patients treated , including isolated instances
 
 
Adverse effects:
Gastrointestinal Disorders
very common
Nausea , vomiting and diarrhea , abdominal pain, loss of appetite. This usually occurs at the beginning of treatment and resolved spontaneously in most cases. In order to avoid these symptoms , it is recommended Siofor 850 be taken during or after meals two or three times a day, the dose is gradually increased .
If complaints continue for a long time , consult your doctor .
Common
metallic taste
 
 
Metabolism and nutrition disorders
very rare
Severe metabolic disorders due to occurrence of lactic acidosis. Signs of this can be vomiting and abdominal pain, which may be accompanied by muscle aches and cramps , or severe malaise (see " Special warnings " ) .
Suspicion of lactic acidosis, please consult your doctor and discontinue Siofor 850 .
 
Disorders of the skin and subcutaneous
very rare
Redness of skin (mild erythema ) in patients with drug intolerance .
Tell your doctor or pharmacist if you notice any side effects not listed in this leaflet .
Keep out of reach of children!
Do not use after the expiry date printed on the package !
 
 
 
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