RASILEZ 300 mg.14 tablets
RASILEZ table. 300 mg
RASILEZ WHAT IS AND WHAT IT IS USED
Rasilez belongs to a new class of medicines called renin inhibitors. Rasilez helps to lower high blood pressure. Renin inhibitors reduce the amount of angiotensin II the body. Angiotensin II leads to constriction of blood vessels, which increases blood pressure. Reducing the amount of angiotensin II allows the blood vessels to relax, which lowers blood pressure.
High blood pressure increases the workload of the heart and arteries. If this continues for a long period of time, can damage blood vessels in the brain, heart and kidneys, and can lead to stroke, heart failure, heart attack or kidney failure. Lowering blood pressure to normal reduces the risk of developing these diseases.
BEFORE YOU TAKE RASILEZ
Do not take Rasilez
if you are allergic (hypersensitive) to aliskiren or any of the other ingredients of Rasilez. If you think you may be allergic, ask your doctor;
if you have experienced any of the following forms of angioedema (difficulties in breathing or swallowing, or swelling of the face, hands and feet, eyes, lips and / or tongue):
angioedema with aliskiren;
angioedema with no known cause;
in the last 6 months of pregnancy or if breastfeeding, see section "Pregnancy and breastfeeding"
if you are taking ciclosporin (a medicine used in transplantation to prevent rejection of a transplanted organ or other conditions, such as rheumatoid arthritis or atopic dermatitis), itraconazole (a medicine used to treat fungal infections) or quinidine ( medicine that is used to correct heart rhythm).
Take special care with Rasilez
if you are taking diuretics (a type of medicine known as water tablets, which increases the amount of urine);
if you have impaired kidney function;
if you experience angioedema (difficulties in breathing or swallowing, or swelling of the face, hands and feet, eyes, lips and / or tongue).
If any of these apply to you, tell your doctor before taking Rasilez.
I do not recommend the use of Rasilez in children and adolescents.
No special dosage recommendations for patients aged 65 years or more.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
You may need your doctor to change your dose and / or to take other precautions if you are taking any of the following medications:
ekarstva to increase the amount of potassium in the blood. These include potassium-sparing diuretics, potassium supplements.
furosemide, a drug belonging to the group known as diuretics or water tablets, which is used to increase the amount of urine.
ketoconazole, a medicine used to treat fungal infections.
verapamil, a medicine used to lower blood pressure, to correct hearth rhythm or to treat angina.
certain types of painkillers known as nonsteroidal anti-inflammatory drugs (NSAIDs).
Taking Rasilez with food and drink
You should take Rasilez with a light meal once a day, preferably at the same time each day. You should not take Rasilez together with grapefruit juice.
Pregnancy and lactation
Do not take Rasilez, if you are pregnant. It is important to talk to your doctor immediately if you think you may be pregnant or plan to become pregnant. Do not breastfeed if you are taking Rasilez.
Ask your doctor or pharmacist before taking any medicine.
Driving and operating machinery
You may feel dizzy and this can affect your ability to concentrate. Before driving, operating machinery, or performing other activities that require concentration, you should make sure you know how you react to the effects of Rasilez.
HOW TO TAKE RASILEZ
Always take Rasilez exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.
People who have high blood pressure often do not notice any signs of the problem. Many may feel quite normal. It is very important that you take this medicine exactly as your doctor has told you to get the best results and reduce the risk of side effects. Keep your appointments with your doctor even if you feel well.
The usual starting dose is one 150 mg tablet once daily.
Depending on how you respond to treatment, your doctor may prescribe a higher dose - one tablet of 300 mg once daily. Your doctor may prescribe Rasilez together with other medicines used to treat high blood pressure.
Route of administration
It is recommended to take the tablets with water. You should take Rasilez with a light meal once a day, preferably at the same time each day. You should not take Rasilez together with grapefruit juice.
If you take more than the dose of Rasilez
If you accidentally take too many tablets Rasilez, immediately consult a doctor. You may need medical attention.
If you forget to take Rasilez
If you forget to take a dose of Rasilez, take it as soon as you remember and then take your next dose at the regular time. However, if it is almost time for your next dose, simply take the next tablet at the usual time. Do not take a double dose to make up for a forgotten tablet.
POSSIBLE SIDE EFFECTS
Like all medicines, Rasilez can cause side effects, although not everybody gets them.
Common (affects less than 1 in 10 patients): diarrhea, joint pain (arthralgia).
Uncommon (affects less than 1 in 100 patients): rash (may also be a sign of an allergic reaction or angioedema - see "rare" side effects below), kidney problems, including renal failure (severe reduction the amount of urine), edema of the hands, ankles or feet (peripheral edema), severe skin reaction (toxic epidermal necrolysis and / or oral ligevitsa reactions - redness, blistering of the lips, eyes or mouth, skin peeling, fever).
Rare (affects less than 1 in 1000 patients): allergic (hypersensitivity) reactions and angioedema (whose symptoms may include difficulty breathing or swallowing, rash, itching, hives or swelling of the face, hands and feet, eyes, lips and / or tongue, lightheadedness), raise the level of creatinine in the blood.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist. You may need to stop taking Rasilez.
HOW TO STORE RASILEZ
Keep out of reach of children.
Rasilez not use after the expiry date stated on the carton and blister. The expiry date refers to the last day of that month.
Do not store above 30 ° C.
Store in the original package to protect from moisture.
The active substance is aliskiren (as hemifumarate) 150 mg.
The other ingredients are crospovidone, hypromellose, magnesium stearate, macrogol, microcrystalline cellulose, povidone, colloidal anhydrous silica, talc, titanium dioxide (E 171), iron oxide black (E 172), iron oxide red (E 172).