Prenessa 8 mg. 30 tablets
The active substance in Prenessa tablets belongs to a group of medicines known as angiotensin converting enzyme (ACE) inhibitors. It works by expanding the blood vessels, making it easier to pump the blood from the heart through them to all parts of the body.
Prenessa Tablets are used for:
Treatment of high blood pressure (hypertension).
To reduce the risk of heart attacks, such as heart attack, in patients with stable coronary heart disease (a condition in which blood supply to the heart is reduced or blocked) and in patients who have already had a heart attack and / or surgery Improving blood supply to the heart by expanding blood vessels that supply it.
2. What you need to know before you take Prenessa
Do not take Prenessa:
if you are allergic (hypersensitive) to perindopril, to any other ACE inhibitor or to any of the other ingredients of this medicine (listed in section 6)
if you have had a hypersensitivity reaction in the past with sudden swelling of the lips and face, neck, possibly on the hands and feet, or asphyxiation or hoarseness after an ACE inhibitor; if you have had a case of angioedema in your family or have had angioedema in other circumstances; if you are pregnant for more than 3 months (also it is advisable to avoid Transmission at the beginning of pregnancy - see Pregnancy section);
if you have diabetes or have impaired kidney function and are being treated with a medicine to lower blood pressure containing aliskiren.
Transferred tablets are not recommended for use in children and adolescents.
Warnings and precautions
Talk to your doctor before taking Prenessa
It is possible that Prenessa is not suitable for you. Therefore, before you start taking Transferra tablets, tell your doctor about the following:
if you have been told you have reduced or blocked blood supply to the heart (unstable angina pectoris)
if you are told that your heart muscle is enlarged or you have a problem with your heart valves;
if you are told that you have a narrowing of the artery that supplies the kidneys with blood (kidney artery stenosis) if you suffer from diabetes,
if you suffer from other kidney, liver or heart disease if you are undergoing dialysis or have had a recent kidney transplant if you are on a salt-restricted diet or if you have had severe vomiting or diarrhea or have used medicines that increase the amount of urine (diuretics)
if you are taking lithium, a medicine used to treat mania or depression if you are taking potassium supplements or salt substitutes containing potassium or other medicines that are associated with increases in serum potassium such as heparin if you undergo a procedure to remove cholesterol from your blood with an apparatus (LDL apheresis),
if you are or will be subjected to treatment to reduce the effects of allergy after bee or ostra sting,
if you have collagenosis (connective tissue disease) such as systemic lupus erythematosus or scleroderma if you are receiving immunosuppressive therapy,
if your blood pressure does not fall sufficiently due to ethnicity (especially in black patients) if you are going to have an operation or a general anesthetic if you suffer from cerebrovascular disease,
if you are taking any of the following medicines used to treat high blood pressure: angiotensin II receptor blocker (ARB) (also known as sartans - for example valsartan, telmisartan, irbesartan), especially if you have kidney problems associated with diabetes, aliskiren.
Your doctor may periodically check your kidney function, blood pressure and the amount of electrolytes (eg potassium) in your blood. See also Do not take Precessa if you are taking any of the following medicines, the risk of angioedema is increased: racemadotril (used to treat diarrhea), sirolimus, everolimus, temsirolimus and other medicines belonging to a class of medicines called mTOR inhibitors (used to avoid rejection of transplanted organs).
You should tell your doctor if you think you are (or may be) pregnant. Transmission is not recommended in early pregnancy and should not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if taken during this period (see Pregnancy).
Other Drugs and Transmission
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Do not take over-the-counter medicines without consulting your doctor. This mainly applies to:
medicines used in colds that contain pseudoephedrine or phenylephrine as active substances,
painkillers, including acetylsalicylic acid (a substance contained in many medicines used as analgesics and lowering tempers
potassium-sparing medicines used to treat heart failure: eplerenone and spironolactone at doses between 12.5 mg and 50 mg per day, medicines used to treat irregular heartbeats (procainamide), medicines to treat diabetes (insulin or oral antidiabetic medicines) , baclofen (used to treat muscle stiffness in diseases such as multiple sclerosis),
gout medicines (allopurinol),
non-steroidal anti-inflammatory drugs (NSAIDs such as ibuprofen, diclofenac), including aspirin to relieve pain, vasodilators including nitrates (medicinal products that cause blood vessel enlargement), heparin (used to thin the blood)
medicines to reduce the immune response of the body or to be administered after transplantation (immunosuppressants such as ciclosporin, tacrolimus), trimethoprim (to treat infections), estramustine (used to treat cancer),
drugs with stimulant action on a particular part of the nervous system, such as ephedrine, adrenaline, noradrenaline or (sympathomimetics), medications for the treatment of mania or depression (lithium)
medicines for the treatment of psychiatric disorders such as depression, anxiety, schizophrenia or other psychosis (tricyclic antidepressants and antipsychotics), injection of gold for the treatment of arthritis (sodium aurothiomalate), medicines most commonly used to treat diarrhea (racemadotril) or to avoid rejection of transplanted organs (sirolimus, everolimus, temsirolimus and other medicines belonging to a class of medicines called mTOR inhibitors). See "Warnings and Precautions *" section.
Your doctor may need to change your dose and / or take other precautions: if you are taking an angiotensin II receptor blocker (ARB) or aliskiren (see also the information titled "Do not take Prestasis" and "Warnings and precautions").
Transfer with food and drink
It is recommended that Transferina be taken before a meal to reduce the effect on the way the medicine works.
Pregnancy and breastfeeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
You should tell your doctor if you think you are (or may be) pregnant. Your doctor will usually advise you to stop taking Presnea before you become pregnant or as soon as you know you are pregnant and will advise you to take another medicine instead of Prenesa. Transfer is not recommended in early pregnancy and should not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if used after the third month of pregnancy.
Tell your doctor if you are breast-feeding or intend to breast-feed. Transfer is not recommended for mothers who are breast-feeding and your doctor may choose another treatment for you if you want to breast-feed, especially if your baby is newborn or was born prematurely.
Driving and using machines
You should not drive or operate machinery until you know how Transmission works. Transmission usually does not affect alertness, but dizziness or weakness due to low blood pressure may occur in some patients, especially at the beginning of treatment or in combination with other antihypertensive drugs.
As a result, the ability to drive or use machines may be impaired. Transferring tablets contain lactose (such as lactose monohydrate)
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
3. How to take Prenesa?
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. If you are not sure, ask your doctor or pharmacist.
The recommended dose for treatment of high blood pressure is 4 mg perindopril (1 tablet Transfer 4 mg) once a day. When necessary, the dose may be increased to 5 mg perindopril (2 tablets Transferase 4 mg or 1 tablet Transferase 8 mg) once a day.
The recommended starting dose for the treatment of stable coronary artery disease is 4 mg perindopril (1 tablet Perindopril 4 mg) once daily; if well tolerated, the dose may be increased to 8 mg peridopril (2 tablets Transferase 4 mg or 1 tablet Transferase 8 mg) once daily.
Take the tablet with a glass of water, preferably at the same time each day, in the morning, before a meal.
During treatment, your doctor will adjust the dose according to the treatment effect as well as your needs.
The dose may be lower than usual and will be determined by a physician:
in elderly patients, in patients with renal impairment,
in patients with high blood pressure caused by narrowing of the arteries supplying blood to the kidneys (Renovascular hypertension), patients who were treated concomitantly
How do you store Prenessa?
Keep out of the reach and sight of children.
Do not use Transferra after the expiry date which is stated on the carton and blister after "EXP / EHR:". The expiry date refers to the last day of that month.
Store in the original package in order to protect from light and moisture. Store below 30 ° C.
Do not dispose of medicines in the sewer or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Contents of the kit and additional information
What does Prenessa contain:
The active substance is tert-butylamine perindopril (perindopril tert-butylamine). Each tablet contains 8 mg of tert-butylamine perindopril, equivalent to 6,676 mg perindopril.
The other ingredients are: calcium chloride hexahydrate, lactose monohydrate, crospovidone type A, microcrystalline cellulose, silica, colloidal anhydrous and magnesium stearate.
What it looks like and what the pack contains:
The tablets are white to off-white, round (12 mm in diameter), slightly biconvex, on one side with scored tablets, bevelled edges. The divider is only for ease of breaking and for easier swallowing, not for splitting in equal doses.
Transferred 8 mg tablets are available in cartons of 10, 14, 28, 30, 50, 56, 60, 90 and 100 tablets in blisters.
Not all pack sizes may be marketed.