Pregnyl amp. 5000 IU 2 ml. 1amp

Pregnyl amp. 5000 IU 2 ml. 1amp
€ 39.00
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PREGNYL contains a hormone known as human chorionic gonadotropin (or briefly hCG) at a dose of 500, 1500 or 5000IU (international units) for ampoule.

Pregnyl amp. 5000 IU 2 ml. 1amp
 
YOUR MEDICINE
 
Medication that has been prescribed is called PREGNYL.
 
PREGNYL contains a hormone known as human chorionic gonadotropin ( or briefly hCG) at a dose of 500 , 1500 or 5000IU ( international units ) for ampoule.
 
PREGNYL has an impact only if it is administered by injection . It is a dry product in a glass ampoule , which is to be dissolved in the solvent contained in the other vial . Furthermore hCG dry substance contains mannitol, disodium hydrogen phosphate , sodium dihydrogen phosphate, and sodium carboxymethylcellulose . Solvent contains sodium chloride (° Mg) and distilled water (1ml).
 
PREGNYL belongs to a group of medicines called gonadotropins. These are hormones that are essential for fertility and reproduction .
 
 
 
HOW DOES PREGNYL AND WHAT IT IS USED
 
PREGNYL exhibit activity as luteinizing hormone (LH), which plays a major role in natural reproduction. Together with follicle stimulating xopMOH (FSH), LH is required for proper growth and development of ova in the female for the production of sperm in the male , and the production of hormones in both genders .. On the back of this leaflet you will find more information about PREGNYL and its use.
 
 
 
BEFORE YOU USE PREGNYL
 
In women :
 
DO NOT USE PREGNYL, if:
 
• You are allergic to gonadotropins or any of the substances contained in PREGNYL.Strogoto observation of patients from doctors is very important. Usually this includes regular reviews of ovaries with ultrasound and blood tests. The results of these tests and examinations will allow the physician to select the most appropriate daily dosage of FSH- preparations. This is important , because if the dose of FSH administered is too high , the ovaries are stimulated over , which very rarely can lead to dangerous complications. Such over- stimulation may begin with pain in the abdomen, which is an important warning, especially if there is also polycystic (presence of multiple cysts ) of the ovary . Regular monitoring of the response of the body with the gonadotropin treatment allows the physician to prevent the occurrence of over- stimulation. If you experience abdominal pain , consult your doctor.
 
 
 
DO NOT USE PREGNYL, if:
 
• You are allergic to gonadotropins or any of the substances contained in PREGNYL.
 
• There is established an androgen -dependent cancer - prostate cancer or breast cancer or suspected ones.
 
Additional monitoring by a physician is recommended for the treatment of men who have not yet entered puberty. This is necessary because PREGNYL can stimulate increased production of the male sex hormone testosterone , which can lead to premature onset of puberty and stopping rastezha.Redovni examinations are necessary , and in some other cases . So be sure to consult your doctor if you have suffered or are suffering from :
 
• A disease of the heart or blood vessels in men - high blood pressure;
 
• A disease of the kidneys;
 
• Epilepsy ;
 
• Migraine headaches.
 
No evidence of interference with the operation of PREGNYL coadministration of other drugs.
 
Pregnancy.
 
If after treatment with gonadotropin pregnancy occurs, it is likely to be multiple and having twins . Slightly increased risk of ectopic pregnancy in women with damaged fallopian tubes. In women undergoing fertility treatment have a slightly increased risk of a miscarriage.
 
Pregnyl should not be used during breastfeeding.
 
Ability to drive and use machines. Existing evidence PREGNYL no effect on alertness and concentration.
 
 
 
 
 
The medicine
 
This medication is given by injection into a muscle that is made by a doctor or nurse or subcutaneous injection , which you can do yourself or Spomolite your partner about it. Your doctor will give you relevant instruktsii._V what dose ? Dose will be determined by your lekar.Obiknoveno in women apply an injection to induce ovulation and up to three for hormonal support the development and normal functioning of the so-called " yellow body " in the ovaries.
 
In men , depending on the symptoms , the injections are made several times per week for several weeks or months.
 
How are the injections ?
 
Before use, the dry substance is dissolved in the solvent. Injections are given slowly into a muscle (eg seat , upper leg or upper arm ) or subcutaneously ( under the skin fold of the abdominal wall , for example) .
 
 
 
Overdose.
 
Toxicity PREGNYL very niska.Pri people found free from symptoms of acute overdose .
 
 
 
POSSIBLE SIDE EFFECTS OF PREGNYL
 
There is evidence that the use of urinary gonadotropins may occur local reactions at the injection site such as pain, redness, swelling , itching and bruising . Sometimes reported the occurrence of allergic reactions manifested by pain and rash at the injection site . In some cases, the rash is generalized and is accompanied by fever.
 
In women :
 
If your ovaries were stimulated too much with FSH- detergent and then is supplied PREGNYL, this can lead to unwanted ovarian over- stimulation. It can present with abdominal pain, accompanied by nausea and diarrhea. These conditions are very rare , and the risk of their occurrence can be reduced by carefully monitoring the development of the eggs during the treatment . If you develop severe abdominal pain , be sure to report it to your doctor, even if it 's just a few days after the last inzhektsiya.Pri men may show a fluid , which is manifested by swelling of the ankles. Sometimes you may experience breast enlargement . If any of these symptoms appear sure to tell your doctor.
 
 
 
HOW TO TAKE CARE OF YOUR MEDICINE
 
PREGNYL Keep in the original container , in the dark at 2 to 8 C, out of reach of children. If the solution obtained after mixing contains particles or is cloudy , the preparation should not be used. The expiry date is marked on the packaging with " exp . " Do not use the drug after this date
 
MORE ABOUT PREGNYL
 
PREGNYL contain human chorionic gonadotropin extracted from the urine of pregnant women, and having an activity of luteinising hormone (LH), which is produced by the pituitary gland of males and females. Together with other pituitary hormone follicle stimulating hormone (FSH) - LH controls the reproductive organs ( ovaries in women and testes in males). Women produce FSH and IH monthly oocyte maturation in one ovary . LH is required for ovulation , i.e. the release of the egg. If the body does not produce enough of these hormones that can lead to infertility. The reasons for it can be and out FSH and LH. Hormonal preparations containing FSH ( and as the case may be - LH) may be used to support the treatment of infertility in the ovulation induction or controlled ovarian ( ovarian ) hyperstimulation ( in vitro fertilization ( fertilization )-IVF, gamete intrafallopian transfer - GIFT and intracytoplasmic sperm injection - ICSI). Daily injection of the preparation will cause maturation of the ovum . Her latest release is supported by applying PREGNYL. Since nature can not be reproduced with absolute precision in the treatment of these hormones can be separated several eggs . This increases the possibility of multiple pregnancy ( twins) . Within the assisted reproduction programs PREGNYL be administered after onset of ovulatsiyata.Pri men , PREGNYL used alone or in combination with FSH in cases of insufficient development of the gonads , delayed puberty or when there are disturbances in the formation of sperm. Since the entire process of development of sperm lasts about 74 days , treatment should be continued for at least 3 months before being confirmed positive promeni.V some cases PREGNYL can be applied in boys in which one or both testicles have not descended into madnata bag.
 
 
 
SOME GENERAL RULES FOR USE OF DRUGS
 
1. This medication is prescribed for treatment of your present condition. It must not be used for treatment of other diseases.
 
2 . Do not give your medicine to other people and do not take drugs prescribed for another.
 
3 . Every doctor who examined you saying what medication you are taking right now. Always wear inside a card on which is written what medications are you currently taking . This can be very important in case of an accident.
 
4 . Make sure to give the people with whom you live or are caring for you to read this leaflet . The information that is provided below the label will be printed in a way that separates it from all other information about the patient .
 
 
 
Physician Information
 
1.1 Posology and method of administration
 
Dosage in women :
 
• Induction and training ovulaiiyata follicle puncture
 
One injection of 5000 to 10000 IU PREGNYL to complete treatment with FSH- preparation .
 
• Maintenance of luteal phase
 
Two or three consecutive injections of 1000-3000 IU was administered for a period of 9 days after ovulation and embryo transfer ( for example on day 3 , 6 and 9Next ovulation induction) .
 
 
 
Dosage in the male
 
• Hipogonadotuopen hypogonadism
 
1000 -2000IU PREGNYL, 2-3 times a week. If the main problem is infertility can be applied and FSH- containing preparation (75 IU daily or 2-3 times a week. Treatment should continue for at least 3 months before any improvement in spermatogenesis . Then treatment can be continued with administration of hCG. during treatment should be discontinued testosterone replacement therapy , if administered one.
 
• Delayed puberty
 
1500 IU 2-3 times per week for at least 6 months.
 
• Cryptorchidism
 
- less than 2 years of age : 250IU twice a week for six weeks ;
 
-2-6 Years : 500-1000 IU twice weekly for 6 weeks
 
, over 6 years: 1500 IU twice weekly for 6 weeks.
 
 
 
Method of administration
 
The dry substance was dissolved by adding solvent. The solution thus obtained since PREGNYL is slowly injected , intramuscularly or subcutaneously.
 
After opening the ampoule can not be resealed in a way ensures that the sterility of the contents should be used immediately.

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