Papaverine. 20 mg. 1 ml. 10 ampules

Papaverine. 20 mg. 1 ml. 10 ampules
€ 9.00
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Papaverinum hidrohlorikum 2% reduces the tonus of the smooth muscles i.spazama of arteries, as well as extravascular smooth muscle of the bronchi, stomach, intestines,, ureter,. biliary tract, uterus. 

Papaverine. 20 mg. 1 ml. 10 ampules 

Contents of the ampoule 20 mg / ml - 1 ml:
Active substance : Papaverine ( like papaverine hydrochloride 20 mg / lml)
Excipients: Ascorbic acid , anhydrous sodium sulfite , sodium metabisulfite , hydrochloric acid lmol / 1, water for injections.
PHARMACEUTICAL FORM AND Pharmacotherapeutic group
Solution for injection .
Papaverinum hidrohlorikum 2% reduces the tonus of the smooth muscles i.spazama of arteries , as well as extravascular smooth muscle of the bronchi , stomach, intestines , , ureter , . biliary tract , uterus .

In which cases can be applied Papaverinum hidrohlorikum 2% ?
Conditions associated with spasm of the gastrointestinal and genitourinary road, vascular spasms of central and peripheral blood vessels. Disorders of cerebral circulation. Alone or in combination with phentolamine for treatment of erectile function impaired .

In which cases should not apply the product ?
Hypersensitivity to the active substance or to any of the excipients , AV- block ( conduction disorder of the heart) , myocardial infarction in the acute stage , ritymni irregular heartbeats , recent stroke , increased intracranial pressure , impaired liver function, glaucoma (increased intraocular pressure), children up to 30 months , and intravenous under 15.
The product should not be used in patients with Parkinson's disease taking levodopa because of the risk of worsening of the disease.

When the product should be administered with caution ?
Be used with caution in liver disease. Treatment should be discontinued at the onset of symptoms of liver disorders ( abnormal liver function tests ), some gastrointestinal complaints ( lazy bowel ) , jaundice or eosinophilia (an increase in certain white blood cells) or . an intramuscular or intravenous administration is necessary to monitor heart function by electrocardiogram .
It should be borne in mind that the performance of Papaverinum hidrohlorikum 2% can be reduced in smokers .
The presence of sulfites ( metabisulfites ) as excipients in the medicinal product may cause allergic reactions, including anaphylactic symptoms and bronchospasm in susceptible people, especially those with a history of asthma or allergy.
Pregnancy and lactation

It is not known whether Papaverinum hidrohlorikum 2% may adversely affect reproductive capacity or cause fetal harm when administered to pregnant women. Although there are no reports linking the use in pregnant women with possible defects , it is only assigned in cases where the potential benefit to pregnant women exceed the potential risk to the fetus.
It is not known whether Papaverinum hidrohlorikum , 2% is excreted in breast milk. Probability of its excretion can not be excluded completely. To this . now, however, there was no message arising problem.s infants .
Impact on alertness in drivers and work with machines
Papaverinum hidrohlorikum - 2% should be used with caution when driving or operating machinery due to the possible sedative ( calming ) effect.
Drug interactions.

You should inform your doctor in case of any concomitant medicinal products in order to avoid any possible interaction between them.
What other drugs affect the action of Papaverinum hidrohlorikum 2% ?
By concomitant use of products that lower blood pressure may intensify this effect.
The effect of Papaverinum hidrohlorikum 2% on the smooth muscle is removed when co-administered with morphine. Antispasmodic action Papaverinum hidrohlorikum 2% can be enhanced by barbiturates ( sleeping pills ) , neuroleptics ( drugs that affect the central nervous system) , narcotic and non-narcotic painkillers .
Papaverinum hidrohlorikum 2% mrzhe reduce the effect of . levodopa (product for the treatment of Parkinson's disease) when co-administered .
Activity Papaverinum hidrohlorikum 2% reduced when coadministered with sulfonamides .
It can be combined successfully with phenobarbital diol novphylline atropine .
The dose and duration of treatment is determined by the doctor depending on the severity of the disease and tolerability of the drug.
Papaverinum hidrohlorikum 2% is administered parenterally , intravenously, intramuscularly and subcutaneously. Intravenous route of administration (1-2 ml 2% solution) is recommended when looking for a quick effect. Inject slowly and gently for 1 - 2 minutes to avoid undesired effects. Subcutaneous and intramuscular dose is administered in 1-2 ml of 2% solution .
Parenteral doses range from 20 to 40 mg, and can be injected in 3 h.
 The maximum single dose for subcutaneous , intramuscular and intravenous administration is 0,1 g, the maximum daily dose is in the range of 0,3 g
In children, the dosage is l, 5 mg / kg 4 times daily weight intramuscularly or intravenously . For children up to 15 years contra - venous administration.
- In . Impotence can be administered in a single dose intracavernous 20-40 -mg, but not higher than 60 mg. In combination with phentolamine should be administered more than 3 times per week.
What side effects may occur when applying Papaverinum hidrohlorikum 2% ?
In the application of this product may experience adverse reactions :
- Cardiovascular system - fast heart rate , ventricular premature complexes ( palpitations ) , atrioventricular block ( conduction disorder of the heart) , hypotension ( low blood pressure).
- Digestive system - dry mouth, nausea , abdominal discomfort, constipation or diarrhea, anorexia ( loss of appetite ) , elevated liver enzymes;
- Nervous - tiredness, dizziness, sedation ( calming ) , drowsiness, headache.
- Respiratory system - respiratory disease - skin - facial flushing, skin rash , sweating . Intracavernosal administration may cause . Dose-dependent priapism .
- For all adverse , effects , including side effects not listed in this leaflet immediately tell your doctor.
What to do if Papaverinum hidrrhlrrium 2% was administered at very high doses ( intentional or accidental overdose ) ? . Symptoms of overdose Papaverinum hidrohlorikum 2% include vasomotor ( vasodilation ) instability , flushing, weakness, nausea , diarrhea , vomiting, CNS depression , nystagmus ( involuntary rhythmic movements of the eyeballs ) , lightheadedness , dizziness, fast heart rate .
A careful control of the general condition of the patient , the condition of the airways , data from blood gas analysis and clinical laboratory tests . When seizures may need including diazepam . In the hypotensive effect of 2% Papaverinum hidrohlorikum appointed intravenous fluids , vasopressor or inotropic agents (eg dopamine) .
Storage Instructions

In original packaging in a dry and dark place at a temperature not higher than 25 ° C.

Two years from date of manufacture.
Do not use after expiry date

€ 9.00
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