PULMOZYME inhaler 1000 U ml. 2.5 ml. 6. dose
PULMOZYME inhaler 1000 U / ml. 2.5 ml. / 6. dose
What is Pulmozyme?
Pulmozyme contains active substance dornase alpha (also known as recombinant human DNase I or rhDNase), constituting a protein produced artificially , similar to the natural protein in the body called DNase. Pulmozyme works by helping to dissolve thick mucus produced in the lungs of patients with cystic fibrosis ( CF ) . Each single use vial contains 2500 U (2.5 mg) dornase alpha -active substances and calcium chloride dihydrate, sodium chloride and water. Pulmozyme is a clear colorless solution for inhalation. Ampoules in packs of 6 and 30 .
For what use Pulmozyme?
Pulmozyme is used to treat patients with cystic fibrosis. It helps to break the thick mucus in the airways and thereby improves lung function. Pulmozyme is suitable for patients with forced vital capacity greater than 40% of the rate and over 5 years for improvement of lung function.
When not to apply Pulmozyme?
If you are allergic to Pulmozyme or any of it contains substances.
When you need to be especially careful when treated with Pulmozyme?
Tell your doctor if you are taking other medicines, including those you have bought without a prescription . This is especially important as the simultaneous use of more than one drug may intensify or weaken the effect of the drugs. It is possible to continue the standard treatment of cystic fibrosis, while taking Pulmozyme ( e.g. , antibiotics, bronchodilators, pancreatic enzymes , vitamins , corticosteroids and analgesics ) .
Pulmozyme should not affect your ability to drive or operate machinery.
Pulmozyme Can be used during pregnancy and lactation ?
The safety of Pulmozyme in pregnant women. Therefore, you should inform your doctor if you are pregnant , think you are pregnant or intend to become pregnant. Your doctor will decide whether to make treatment with Pulmozyme. It is not known whether this medication passes into breast milk . Your doctor will decide whether you are using Pulmozyme, when breast-feeding. Mothers who do not breastfeed may conduct treatment with Pulmozyme.
How should you take Pulmozyme?
Always use Pulmozyme in the manner prescribed by your doctor. Usually the dose for adults and children is the content of one ampoule inhaled daily . Experience in children under five years is limited . In elderly ( over 21 years) may need Pulmozyme inhalation twice daily for one ampoule. Your doctor will decide which is the most appropriate dose for you.
This drug should be administered with a nebulizer with compressed air ( jet ) . Most ultrasonic nebulizers are inappropriate. Your doctor can recommend the appropriate type . Break the top of one ampoule Pulmozyme and empty the contents into the chamber of a jet nebulizer before use. Then follow the instructions for using the nebulizer and compressor.
When preparing a jet nebulizer for administration of Pulmozyme, please remember the following important features :
Before use, make sure it is clean nebuliser .
Do not dilute solution Pulmozyme.
Do not mix in jet nebulizer Pulmozyme with other drugs or solutions.
Discard any unused solution should not use it again.
If this is reusable nebulizer , be sure to clean it after use. The manufacturer of nebulizer can offer advice on the best way to clean the nebulizer after administration of Pulmozyme.
To obtain the maximum effect , Pulmozyme should be inhaled daily . If you forget to take a dose, take it as soon as you remember and then continue as before. You should not take more than one dose a day, unless your doctor tells you .
During treatment with Pulmozyme should continue with standard chest physiotherapy . It is also important to see your doctor in accordance with his instructions .
Pulmozyme overdose or if someone else take this medicine immediately contact your doctor , pharmacist or nearest hospital .
What are the possible side effects of treatment with Pulmozyme?
Like all drugs , Pulmozyme can cause side effects, although not everybody gets them .
The most commonly reported sore throat, chest pain and hoarseness . These effects are not serious . In single cases have been reported laryngitis (inflammation of the vocal cords ) , conjunctivitis and skin rash with or without itching. Fever, runny nose and sneezing, shortness of breath and irritation in the stomach were observed in severely ill patients in clinical trials. When you begin treatment , your lung function may deteriorate and the amount of secretion to increase above normal - this effect is usually temporary and is seen in the use of any drug that is given as an aerosol ( droplets in air ) .
If you have concerns about any of these or other side effects , check with your doctor.
How should I store Pulmozyme?
Ampoules should be stored in a refrigerator at 2-8 º C
protected from strong light .
You should avoid exposure to high temperatures. Ednokratkno exposure to high temperature ( up to 24 hours at a temperature not higher than 30 ? C ) does not damage the product.
Keep this medicine out of the reach and sight of children.
Do not use this medicine after the expiry date ( gGoden to) stated on the packaging . Remainder back to the pharmacy. Keep it only if your doctor tells you to.