PIRAMEM 400 mg. 60 capsules

ACTAVIS
PIRAMEM 400 mg. 60 capsules
€ 19.00
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What is Piramem and what it is used
Piramem the group consisting of nootropic drugs, derivatives of gamma-aminobutyric acid. Piramem improves and restores violations in cognition (learning ability, memory, attention and mental performance) due to brain diseases and intoxications (poisoning). It does not have psychostimulant and soothing effect. Piramem improves the rheological properties of the blood.

Piramem apply to:
Adults
Improving impairment of memory and attention, and the lack of motivation due to brain diseases and disabilities (so called psycho-organic syndrome);
Treat sudden, involuntary muscle contractions (ie cortical (cortical) myoclonus), alone or in combination with other drugs;
Treatment of vertigo and related imbalances, with the exception of dizziness of vascular or mental origin;
For prophylaxis and remission of sickle cell vaso-occlusive crisis (ie vascular crisis - blockage of small blood vessels) in sickle cell anemia (an inherited disease in which abnormal structure of the hemoglobin and changed the shape of red blood cells) .
children
Treatment of speech disorders (dyslexia), in combination with other appropriate measures such as speech therapy;
For prophylaxis and remission of sickle cell vaso-occlusive crisis.
2. What you need to know before taking Piramem
Do not take Piramem if:
you are allergic to the active substance or any of the other ingredients of this medicine (listed in section 6);
You have a brain hemorrhage;
suffer from kidney failure last stage;
suffer from so Huntington's chorea.
Warnings and Precautions
Talk to your doctor or pharmacist before taking Piramem:
if you have heavy bleeding or if your risk of bleeding is increased (eg. you have gastrointestinal ulcers, bleeding disorders in the past you had bleeding in the brain have undergone major surgery (including dental));
have severe kidney disease. Your doctor can assess the need for change in the daily dose, if you have any disturbances in the function of the kidneys. In elderly patients need periodic monitoring of renal function;
it is necessary to bear in mind that the abrupt discontinuation of treatment in patients with myoclonus may lead to recurrence of the symptoms or its deterioration.
Administration of a daily dose lower than recommended in patients with sickle cell anemia may provoke renewed crisis.
It is recommended that elderly patients to regularly visit your doctor to adjust the dose if necessary.

Other medicines and Piramem
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
With concomitant piracetam with thyroid hormones is reported occurrence of confusion, irritability and sleep disturbances in.
Concomitant treatment with anticoagulants and antiplatelet aggregants (anti-clotting drugs and medication to thin the blood) including acetylsalicylic acid (low dose) increases the risk of bleeding.

Piramem with food, drinks and alcohol
No evidence of the need for special diets or restrictions on certain types of foods and beverages during treatment with the product.

Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.

pregnancy
There are no adequate data from the use of piracetam in pregnant women. Not recommended use of the product during pregnancy unless clearly necessary after the discretion of the physician.

breastfeeding
Piracetam is excreted in human milk, therefore not recommended its use during lactation. In the event that treatment with the product is essential, breast-feeding should be discontinued.

Driving and using machines
Some of the side effects (drowsiness, depression) related to taking the product can have an adverse effect on the ability to drive and use machines, which must be taken into account.

Piramem contains lactose monohydrate, wheat starch and E110
Piramem 400 mg film-coated tablets and Piramem capsules contain lactose monohydrate. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this product.
Piramem 400 mg capsules contain E110, which might cause allergic reactions. Piramem 400 mg film-coated tablets contain wheat starch. It is suitable for people with celiac disease (gluten enteropathy). Patients with wheat allergy (different from celiac disease) should not take this product.

3. How to take Piramem
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.

Adults
Treatment of myoclonus (sudden involuntary muscle contractions) with cortical origin initial daily dose is 7,2 g, which increased by 4,8 g every 3-4 days up to a maximum daily dose of 24 g, divided into 2 or 3 accepts. Treatment with protivomioklonichni other medicinal products should be maintained at the same dose.
Depending on the clinical outcome achieved if possible dosage of other such medicinal products should be reduced. Once started, treatment with piracetam should be continued as long as the original cerebral disease continues. Every 6 months should attempt to lower the dose or treatment discontinuation.
Caution - patients with kidney problems need to take lower doses (see. Precautions for use). The duration of treatment depends on the nature of the disease and the response you your symptoms. If you think the effect of the drug is too strong or too weak, talk to your doctor or pharmacist.
Symptomatic treatment of psihoorganichen syndrome (deterioration of mental activity)
The recommended daily dose ranges from 2.4 to 4,8 g, divided into 2 or 3 doses. Treatment begins with daily doses of 4,8 g piracetam during the first few weeks, after which the daily dose was decreased to 2,4 g.

Treatment of vertigo (dizziness and tinnitus)
The recommended daily dose ranges from 2.4 to 4,8 g, divided into 2 or 3 doses.

Prophylaxis and remission of sickle cell vaso-occlusive crisis
Recommended daily dose for prophylaxis is 160 mg / kg taken orally, divided into 4 doses.
The recommended daily dose for remission is 300 mg / kg, administered into a vein divided into 4 (use the forms for injection and infusion administration.
Daily dose lower than 160 mg / kg or irregular intake may lead to renewed crisis.

Children and adolescents
Treatment of Dyslexia (difficulty in reading and understanding of reading) in combination with speech therapy
For children aged 8 years and adolescents recommended daily dose is 3,2 g, in two divided doses.

For prophylaxis and remission of sickle cell vaso-occlusive crisis
Recommended daily dose for prophylaxis is 160 mg / kg taken orally. The recommended daily dose for remission is 300 mg / kg, administered into a vein.
Daily dose lower than 160 mg / kg or irregular intake may lead to renewed crisis.
Piracetam can be administered to children over 3 years suffering from sickle cell anemia at the recommended daily dose (in mg / kg). Piracetam has been administered to a limited number of children aged 1 to 3 years.

Method of administration
Piramem tablets and capsules should be administered orally and be swallowed with liquid. Can be taken with or without food. Recommended daily dose be taken two to four times.

Duration of treatment
You should take Piramem as long as advised by your doctor. In the treatment of chronic diseases optimum effect is usually achieved after 6 to 12 weeks.

If you take more than the amount Piramem
If you accidentally or on purpose you use more than the prescribed dose, contact your doctor immediately or go to the nearest hospital. Do not take your medicine more often or for longer than prescribed to avoid overdose.

If you forget to use Piramem
Do not take a double dose to make up the missed dose. Apply the usual dose as soon as possible after you remember and continue treatment as usual.

If you stop taking Piramem
To avoid the resumption of complaints discontinuation of treatment with Piramem should be gradual - every 2 days the dose was decreased by 1,2 g.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them. The occurrence of any of the following effects and they worry you, tell your doctor.

Frequencies they can be:
Very common (affecting more than 1 in 10 patients);
common (affects up to 1 in 10 patients);
Uncommon (affects up to 1 in 100 patients);
rare (affects up to 1 in 1000 patients);
very rare (affects up to 1 in 10,000 patients);
not known (from the available data can not be estimated).
During treatment with piracetam possible following adverse reactions:
common:
nervousness;
Increased physical activity (hyperkinesia);
Weight gain.
Uncommon:
depression;
drowsiness;
Weakness (asthenia).
Not known:
Disturbances in blood clotting (bleeding disorders);
Severe allergic reaction that causes breathing difficulties and dizziness, hypersensitivity;
Agitation, anxiety, confusion, hallucinations;
Difficulty with coordination of movement, impaired balance, aggravated epilepsy, headache, insomnia;
Dizziness (vertigo);
Pain in the abdomen, pain in the upper abdomen, diarrhea, nausea, vomiting;
Severe allergic reaction which causes swelling of the face or throat (angioneurotic edema), dermatitis (inflamed and irritated skin), pruritus, urticaria.

5. How to store Piramem
At temperatures below 25 ° C.
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton. The expiry date refers to the last day of that month.
Do not use this medicine if you notice changes in the appearance of tablets or capsules.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer use. These measures will help to protect the environment.

6. Contents of the pack and other information
What Piramem:
Piramem 400 mg hard capsules
The active substance is piracetam (piracetam) 400 mg.
The other ingredients are lactose monohydrate; silica colloidal anhydrous (Type R-972); silica colloidal anhydrous (type 200); talc; magnesium stearate; gelatin capsule (gelatin, E104, E171, E110).

Piramem 400 mg tablets
The active substance is piracetam (piracetam) 400 mg.
The other ingredients are lactose monohydrate; cellulose, microcrystalline; wheat starch; silica colloidal anhydrous; magnesium stearate; copovidone; talc.
The composition of the film coating: methacrylic acid-ethyl acrylate copolymer (1: 1), talc, titanium dioxide, macrogol 6000, polysorbate 80.

Piramem 800 mg tablets
The active substance is piracetam (piracetam) 800 mg.
The other ingredients are copovidone, crospovidone, magnesium stearate.
The composition of the film coating: methacrylic acid-ethyl acrylate copolymer (1: 1), talc, titanium dioxide, macrogol 6000, macrogol 400, polysorbate 80, silica colloidal anhydrous, magnesium stearate.

Piramem looks like and contents of the pack
Piramem 400 mg hard capsules
Yellow, solid, cylindrical capsules.
10 pieces in blister 6 blisters in a box.

Piramem 400 mg tablets
White or almost white, round biconvex tablets.
10 pieces in blister 4 blister pack.
€ 19.00
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