PANCEF 400 mg. 10 tablets
PANCEF 400 mg. 10 tablets
PANCEF WHAT IS AND WHAT IT IS USED
Pancef (cefixime) is an oral antibiotic cephalosporin. Cefixime showed activity, both in vitro and in clinical infections against most strains of the following organisms: Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, Moraxella catarrhalis, Escherichia coli, Proteus mirabilis, Neisseria gonorrhoeae and the like.
Pancef recommended for the treatment of infections caused by cefixime-sensitive microorganisms, namely:
acute infections of the upper and lower respiratory tract, including. pharyngitis and tonsillitis, acute bronchitis and acute exacerbations of chronic bronchitis, pneumonia, acute and exacerbated chronic sinusitis;
urinary tract infections;
uncomplicated gonorrhea (cervical / urethral).
2 BEFORE YOU TAKE PANCEF
Do not take Pancef if:
you are allergic (hypersensitive) to cefixime, other cephalosporin antibiotics, or any of the excipients of Pancef.
Take special care with Pancef if:
you have or have ever had an allergic reaction to penicillin, other drugs or in case of other allergic manifestations (allergic reaction may include rash, itching, swelling, unusual joint pain, or difficulty breathing). If an allergic reaction to the drug should be discontinued;
have kidney problems or diseases of the gastrointestinal tract (especially colitis).
Continuous treatment with cefixime may lead to superinfection with non-susceptible organisms.
If severe watery diarrhea, accompanied by fatigue and fever (pseudomembranous colitis), stop using Pancef and tell your doctor.
Pancef tablets should not be administered to children under 12 years.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
It is essential if you are taking any of the following medicines:
probenecid - delays the elimination of cefixime and increases plasma concentration;
Carbamazepine - cefixime increases the concentration of carbamazepine in concomitant;
aminoglycosides - aminoglycosides increase the risk of kidney damage;
anticoagulants - cefixime may prolong prothrombin time.
Taking cefixime can lead to false positive some laboratory tests.
While taking the drug should not be done protivotifna vaccination.
Taking Pancef with food and drink
Pancef can be taken regardless of meals.
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
The medicinal product is not recommended for pregnant women, especially during the first three months and the last six weeks, and in nursing mothers should proceed with caution.
Driving and using machines
Cefixime not affect your ability to drive or operate machinery.
3 HOW TO TAKE PANCEF
Always take Pancef exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist.
Adults: The usual dose is 400 mg (one tablet) as a single daily oral dose or divided into two equal oral dose of 200 mg (half tablet) every 12 hours.
The treatment time is generally 7-14 days depending on the severity of the infection.
Streptococcal infections are to be treated at least 10 days.
For the treatment of urinary tract infections in women is recommended single dose of 400 mg (one tablet), or three-day treatment. For the treatment of uncomplicated cervical / urethral gonococcal infections recommended single dose of 400 mg (one tablet).
Patients with severe renal insufficiency should not take half the standard dose (200 mg or half a tablet) daily.
If you take more than you should Pancef
If you take more than you should, immediately contact your doctor or pharmacist.
In case of overdose, gastric lavage is recommended. There is no specific antidote. Cefixime can be removed by hemodialysis or peritoneal dialysis.
If you forget to take Pancef
In case of failure of the intake, the next dose should be taken as soon as possible. If it is almost time for your next dose, the missed dose should be skipped and the treatment should continue the established pattern. Do not take a double dose to make up for a missed dose.
If you stop taking Pancef
Do not stop taking medication without consulting your doctor. Do not stop taking Pancef, just because you feel better as the infection may reoccur.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 POSSIBLE SIDE EFFECTS
As with all medications, Pancef can cause side effects, although not everyone gets them.
If any of these symptoms occur, it is important to tell your doctor because if you do not pay attention may occur more serious complications.
Adverse reactions are listed according to their frequency:
Uncommon (affecting less than 1 in 100 patients but more than 1 in 1000 patients): diarrhea, abdominal pain, indigestion, flatulence (bloating), nausea and vomiting, headache, or dizziness.
Rare (affecting less than 1 in 1000 patients but more than 1 in 10,000 patients): hypersensitivity reactions (skin rashes, urticaria, drug fever and itching), transient elevations in ALT, AST and alkaline phosphatase, genital itching, vaginitis, candidiasis.
Very rare (affecting less than 1 in 10 000 patients but more than 1 in 100 000 patients): transient thrombocytopenia, leukopenia and eosinophilia (abnormalities in the number of certain types of blood cells), prolonged prothrombin time, heavy skin reactions such as erythema multiforme syndrome Steven Johnson; reactions resembling serum sickness, pseudomembranous colitis, transient elevations in blood urea nitrogen and creatinine.
If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5 HOW TO STORE PANCEF
Keep out of reach of children.
This medicinal product does not require any special storage conditions. Do not use Pancef film-coated tablets after the expiry date stated on the package (for expiry date abbreviation used). The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6 FURTHER INFORMATION
The active substance is cefixime. Each tablet contains 400 mg of cefixime in form of a trihydrate.
Other ingredients are: starch, pregelatinized; cellulose, microcrystalline; calcium hydrogen phosphate dihydrate; gelatin; corn starch; sodium lauryl sulfate; magnesium stearate; hypromellose; macrogol 4000: titanium dioxide.
Pancef looks like and contents of the pack
Pancef coated tablets are white to slightly pale cream colored oblong, biconvex tablets with a dividing line on one side.
The film-coated tablets are packed in a brown glass bottle. Carton contains 5 or 10 tablets (1 bottle) and the package user.
The film-coated tablets are packed in transparent PVC / TE / PVdC / AI blister. Carton contains 5 tablets (one (1) blister) and Package Leaflet or 10 tablets (two (2) blister) and the package user.