Ovitrelle amp. 0.25 mg. 1 amp
Ovitrelle amp. 0.25 mg. 1 amp
Ovitrelle amp. 0.25 mg. 1amp
Ovitrelle 250 micrograms / 0,5 ml solution for injection in pre-filled syringe.
The active substance is Choriongonadotropin alfa. Each pre-filled syringe contains 250 micrograms / 0,5 ml (equivalent to S 6500).
Druitt ingredients are mannitol, methionine, poloxamer 188, diluted phosphoric acid, sodium hydroxide, water for injections.
Ovitrelle WHAT IS AND WHAT IT IS USED
Ovitrelle is a solution for injection in pre-filled syringe (1 pc. Per pack).
Ovitrelle is a medicinal product containing choriogonadotropin alfa, which is very similar to horionoviya gonadotropin, which naturally occurs in humans, but is created in the laboratory using a special recombinant DNA technology. It belongs to the family of hormones called gonadotrophins, which participate in the normal control of reproduction.
Ovitrelle is used in women undergoing Assisted Reproductive Technologies (APT), such as in vitro fertilization (IVF). Before that apply other medications that cause growth and development of multiple follicles, which eventually produce eggs. Then apply Ovitrelle to induce follicular maturation.
Ovitrelle is also used in women who do not produce eggs (a condition called anovulation) or produce too few eggs (oligoovulatsiya), having already been implemented other drugs to induce follicle development.
BEFORE YOU USE ovitrelle
Before starting treatment, your fertility as well as that of your partner will need to be tested and evaluated.
Do not take Ovitrelle:
if you are pregnant or breast-feeding;
if you increase the ovary or one or more large ovarian cysts;
if you have vaginal bleeding of unknown origin;
If you are diagnosed with cancer of the ovaries, uterus, or breast;
if you have a tumor of the hypothalamus or pituitary gland;
If you have an active thromboembolic disease (severe inflammation of the veins or blood clots in the veins);
if you have a known allergy to this or a similar product or any of its ingredients;
if you have a disease that makes it impossible for the pregnancy (eg lack of uterus, developmental disorders, ovarian fibrosis) or if you are menopausal age;
if you had an ectopic pregnancy in the past three months.
Be especially careful when using Ovitrelle:
Ovitrelle therapy may increase the risk of the syndrome of ovarian hyperstimulation (OHSS) (see also "Possible nizhelani effects"). This condition occurs when the ovaries over-respond to treatment and develop too many follicles. The most common symptom is pain in the abdomen. If you feel pain or discomfort in the abdomen should not take this medicine, but talk to your doctor or nurse as soon as possible. You should not have sexual intercourse for at least 4 days, or use barrier contraception metodi.
Compared with natural conception in patients undergoing this treatment the incidence of multiple pregnancies and births is increased. Most of them are bliztsnatsi. In auxiliary fertilization techniques (APT) number of fruits is related to the number of embryos.
The risk of OHSS or multiple pregnancy is reduced if the usual dose of Ovitrelle and the whole treatment cycle posledyava carefully (eg by ultrasound and blood tests to measure levels of estradiol).
Pregnancy and lactation
If you are pregnant or breastfeeding should not apply Ovitrelle. Taking other medicines:
Please tell your doctor if you are taking or have recently taken any other medicines, even those without a prescription.
HOW TO USE ovitrelle
Always Ovitrelle, strictly following the instructions of your doctor. If you are unsure you should ask your doctor.
Ovitrelle dosage of one pre-filled syringe (250 micrograms / 0.5 sh1) applied once. Your doctor will tell you exactly when you should have a shot.
If you feel that the effect of Ovitrelle is too strong or too weak, you should consult your doctor.
How to apply Ovitrelle?
Ovitrelle is administered by subcutaneous injection. Each prefilled syringe is for single use only and should be used only clear solution without particles.
The injection can be done by your doctor or nurse, but it is also possible you or your partner must be trained to give the injection at home.
If you apply Ovitrelle yourself at home, please carefully read the following instructions:
Wash your hands. It is important that your hands and all objects that use be as clean as possible
Assemble everything you will need. Note that tampons soaked in alcohol are not included.
Find a clean area and lay out everything. two swabs, wipes, one pre-filled syringe containing product;
Immediately inject the solution: Your doctor or nurse will have already instructed you where to inject (ie abdomen or anterior thigh). Clean the chosen area with an alcohol swab. Firmly pinch the skin and insert the needle at an angle of 45 ° to 90 ° using a motion similar to a dart. Inject under the skin just as you were taught. Do not inject directly into a vein. Inject the solution by gently pressing the plunger. Take as much time as you need to inject all the solution. Immediately withdraw the needle and clean the skin with an alcohol swab using a circular motion.
Dispose of all used items.
Immediately after the injection, discard the empty syringe into a suitable container. Any unused solution should be discarded.
If you use more Ovitrelle than you need
If given too much Ovitrelle, the risk of developing the syndrome of ovarian hyperstimulation, which is further described in "Be cautious when using Ovitrelle" and in "Possible side effects". You should consult your doctor in case you observe these symptoms.
If you forget to use Ovitrelle
You should contact your doctor.
POSSIBLE SIDE EFFECTS
Like all medicines, Ovitrelle can have side effects. The majority of adverse reactions reported to date were mild or moderate in nature. The most frequently reported side effects were fatigue, pain and reaction injection.
Syndrome svrahsimulatsiya the ovaries (OHSS) was observed in approximately 4% in clinical trials. Most of these cases were mild or
character. This syndrome is characterized by large ovarian cysts. The first symptoms of this syndrome are pain in the lower abdomen, possibly accompanied by nausea, vomiting and weight gain. In the event of such symptoms as quickly as possible to make careful medical examination.
Commonly reported side effects are abdominal pain, nausea and vomiting, headache, inflammation and reactions at the injection site, dizziness. Diarrhea, depression, irritability, restlessness, and chest pain have also been reported in some cases, but is not considered common.
Ectopic pregnancy, ovarian torsion and other complications may occur as a result of assisted conception techniques that your doctor can use.
Keep out of reach of children.
Store in a refrigerator (2 ° C - 8 ° C). Store in original container. Ovitrelle 250 micrograms solution can be stored at room temperature (at or below 25 ° C) for more than 30 days without being returned to the refrigerator during this time. Ovitrelle should be discarded if not used within 30 days.