Ospen syrup 400 mg. 60 ml

SANDOZ
Ospen syrup 400 mg. 60 ml
€ 12.00
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What is the active substance?
Ospen 400: 5 ml (1 measuring spoon) contains 400 000 IU of benzathine fenoksimetilpenitsilin-
 
What else contains Ospen?
Ospen 400: simethicone, propyl, metilparahidroksi benzoate, tutti frutti flavor, yellow ferric oxide, croscarmellose sodium, anhydrous citric acid monohydrate, magnesium aluminum silicate, trisodium citrate dihydrate, sodium saccharin, sorbitol and water.
Formulation and packaging:
Ospen 400, 750 oral suspension in original packs of 60 and 150 ml.
 
What is Ospen?
Phenoxymethylpenicillin is a highly potent oral penicillin. Acting bactericidal sensitive lroliferirashti microorganisms by inhibiting biosynthesis of cell walls. The spectrum of action of phenoxymethylpenicillin is practically identical to the that of benzylpenicillin. It includes streptococci groups A, C, G, H, L and M, Streptococcus pneumoniae, penicillinase-non producing staphylococci and Neisseriae; Erysipelothrix rhusiopathiae, Listen'ae, corynebacteria, Bacillus anthracis, actinomycetes, streptobacilli, Pasteurellamultocida, Spirillum minus and spirochetes of the species Leptospira, Treponema, Borrelia and other spirochetes, and also reditsaNaimenovanie of the medicinal product: Ospen® 400, 750 also oral suspension sensitive. From enterococcal strains (group B streptococci D) show some sensitivity.
 
What is Ospen?
Ospen used for prevention and treatment of mild to moderate infections caused by organisms susceptible to penicillin:
 
Infections of the ear, nose and throat
Diseases caused by streptococci (scarlet fever, tonsillar angina, Alzheimer's Vinsent, pharyngitis, pharyngotonsillitis purulent nasopharyngitis, acute otitis media, sinusitis) .Infektsii respiratory patishtaBakterialen bronchitis, bacterial pneumonia and bronchopneumonia, except those requiring parenteral therapy.
 
Skin infections
Erysipelas, erizipeloid, pyoderma (eg. Contagious impetigo, furunculosis), abscess, flegmon.Erythema migrans and other clinical manifestations of Lyme disease.
other infections
Bite wounds (eg. The face wounds or deep wounds on the hands) and burns.
 
Prevention of:
Streptococcal infections or complications from them eg. rheumatic fever or chorea minor, arthritis, endocarditis, glomerulonephritis. Bacterial endocarditis in patients with congenital or rheumatic heart problems before and after minor surgery like removing tonsils, removing teeth, etc. Pneumococcal infections in children with sickle cell anemia. In conditions such as severe pneumonia, empyema, sepsis, pericarditis, endocarditis, meningitis, arthritis and osteomyelitis, treatment in the acute stage should be parenteral.
 
When you should not take Ospen?
Known hypersensitivity to penicillins. In patients with known hypersensitivity to cephalosporins should be considered possible cross alergiya.Peroralno application of penicillin is not indicated in patients with gastrointestinal diseases which cause prolonged diarrhea or vomiting, as the absorption of the drug can be namali.Preporachva Caution in patients with allergic diathesis or with bronchial astma.Koga necessary precautions when adopting Ospen? Treatment should be discontinued if allergic reactions occur and to apply the usual means such as adrenaline, antihistamines and corticosteroids.
When staphylococcal infections recommends a bacteriological examination.
For perioperative prophylaxis in patients receiving penicillin, which require to undergo surgery (removal of tonsils, removing teeth, etc.), For the prevention of rheumatism dose should be udvoi.Pri patients undergoing long-term treatment is recommended full blood count and differential count, and liver function and babretsite.Osobeno attention should be paid to the possibility of the development of resistant strains of microorganisms and fungi with continued dosing. Since infectious mononucleosis is a viral disease, it is not appropriate treatment with antibiotics. If, however, be used, may be increased cases of skin obrivi.Poyavata of severe and persistent diarrhea should arouse suspicion of pseudomembranous colitis caused by antibiotics (watery diarrhea with blood and mucus, to diffuse dull cramping abdominal pain, fever and occasionally painful colic). Since this condition can be life-threatening, the adoption of Ospen should be discontinued immediately and to appoint a specific treatment according to the results of bacteriological testing (eg. Oral vancomycin 250 mg four times daily). Adoption of antiperistaltichni products is contraindicated.
 
Warning to diabetics:
Ospen syrup contains no sugar. It contains no artificial sweeteners.
 
What other products influence the effect of Ospen or may be affected by product?
As penicillins act only against proliferating microorganisms, Ospen® should not be combined with bacteriostatic antibiotics. Combinations with other antibiotics should be administered only if the expected synergistic or at least additive effect. Doses of participating in the combination drugs must comply with their effective doses (Exception: in case of a synergistic effect of the combination dose of the drug with higher toxicity can be reduced) .It be considered competitive inhibition of elimination when co-administered with anti-inflammatory, anti-rheumatic, antipyretics (particularly indomethacin, phenylbutazone and salicylates in high doses) or probenetsid.Rezorbtsiyata of Ospen se'namalyava its adoption hrana.Podobno with other antibiotics, Ospen® may reduce the efficacy of oral kontratseptivi.Po time treatment Ospen results of examination of urine glucose by reducing (non-enzymatic methods), and those of the examination of urobilinogen may be a false positive.
 
What special precautions should be taken during pregnancy and lactation?
So far there are no data showing embryotoxic, teratogenic or mugagenen effects when applying Ospen during pregnancy. It should be borne in mind that Ospen can pass into breast milk.
 
 
Dosage, method and duration of administration:
  Ospen dosage depends on the severity of the infection and is determined only by the doctor! How much and how often you can take Ospen? In case there are no special medical prescription, children up to 12 years into 50 000 -100 000 Ill / kg day in three divided doses.
Total dose range:
Children from 3 to 12 months (6-10 kg): 3 times daily Y2 scoop Ospen 400Detsa from 1 to 6 years (10-22 kg): 3 times daily 1 scoop Ospen 400 or 3 times a day 1/2 spoon Ospen 750 children from 6 to 12 years (22-38 kg): 3 times daily 2 scoops Ospen 400 or 3 times daily 1 measuring spoon Ospen 750Lechenieto should continue 2-5 days disappearance of symptoms. The World Health Organization recommends that penicillin streptococcal infections can be administered for 10 days.
 
Special dosage recommendations for prevention:
• prevention of streptococcal infections (e. Scarlet fever): Upon contact, the oral administration of penicillin in therapeutic doses for 10 days may stop disease progression.
• Prevention of relapse in rheumatic fever and / or chorea minor: Children from 3 to 12 months: 2 times a day 1/2 scoop Ospen® 400. Children over 1 year: 2 times daily 1 scoop Ospen 400 or LA volumetric spoon Ospen 750
• Prevention of endocarditis after minor surgical interventions eg. removal of the tonsils, removing teeth: Children weighing up to 30 kg: 30-60 minutes prior to surgery 4 scoops Ospen 400, then after surgery 1 scoop every 6 hours for 2 days or more.
 
Dosage in patients with renal insufficiency:
Since penicillin low toxicity is generally not necessary to decrease the dosage in the case of damage to the kidneys or the liver.
 
What should I do if Ospen was adopted in very large amounts (intentional or inadvertent overdose)?
If you swallow large doses of Ospen®, immediately consult your doctor! Symptoms of overdose largely overlapping side effects. Possible gastrointestinal disorders and disorders of fluid and electrolyte balance.
What side effects can cause the application of Ospen?
Hypersensitivity reactions
Possible allergic reactions: urticaria, angioneurotic edema, erythema multiforme, exfoliative dermatitis, fever, joint pain or anaphylactic shock with collapse and anaphylactoid reactions (asthma, purpura, gastrointestinal symptoms). They are not common and usually much lighter than those of parenteral administration of penitsilin.Pri patients with mycosis, allergic reactions can be triggered by potentiation of allergenicity of metabolites from skin fungi and penicillin.
Gastrointestinal symptoms
Sometimes there is nausea, diarrhea, vomiting, feeling of fullness in the stomach, stomatitis, glossitis. Diarrhea during treatment should arouse suspicion of pseudomembranous colitis (see also "Special precautions").
haematological abnormalities
Eosinophilia, positive results using the direct method Coombs, hemolytic anemia, leukopenia, thrombocytopenia and agranulocytosis is extremely ryadko.Kakvi measures must be taken in relation to side effects? If you notice any of these side effects, please inform your doctor. He / she will decide, depending on their weight, what measures predprieme.Molya tell your doctor if you notice any side effects not listed in this leaflet.
 
Storage Instructions:
Keep out of reach of children! The product should be stored refrigerated (2-8 ° C); keep away from direct light.
The shelf life of the product is printed on the packaging.
Do not use after the expiry date! After first opening the expiry date of the suspension is 14 days under refrigeration.
€ 12.00
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