Ospen 30 tablets 1000 mg

SANDOZ
Ospen 30 tablets 1000 mg
€ 17.00
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What is Ospen?
Phenoxymethylpenicillin is a highly potent oral penicillin. Acting bactericidal sensitive lroliferirashti microorganisms by inhibiting biosynthesis of cell walls. The spectrum of action of phenoxymethylpenicillin is practically identical to the that of benzylpenicillin. It includes streptococci groups A, C, G, H, L and M, Streptococcus pneumoniae, penicillinase-non producing staphylococci and Neisseriae; Erysipelothrix rhusiopathiae, Listeriae, corynebacteria, Bacillus anthracis, actinomycetes, streptobacilli, Pasteurellamultocida, Spirillum minus and spirochetes of the species Leptospira, Treponema, Borrelia and spirochetes other, and also the number of anaerobes (eg. Peptokoki, peptostreptokoki, fuzobakterii, clostridia) are also sensitive. Of enterococcal strains (streptococcus group D) Sams show some sensitivity.
 
What is Ospen?
Ospen used for prevention and treatment of mild to moderate infections caused by organisms susceptible to penicillin:
Infections of the ear, nose and throat
Diseases caused by streptococcus (scarlet fever, tonsillar angina, disease Vinsent, pharyngitis, pharyngotonsillitis purulent nasopharyngitis, acute otitis media, sinusitis).
 
Respiratory tract infections
Bacterial bronchitis, bacterial pneumonia and bronchopneumonia, except those requiring parenteral therapy.
 
Skin infections
Erysipelas, erizipeloid, pyoderma (eg. Contagious impetigo, furunculosis), abscess, flegmon.Erythema migrans and other clinical manifestations of Lyme disease. Other infektsiiRani bites (eg. The face wounds or deep wounds on the hands) and burns.
Prevention of:
Streptococcal infections or complications from them eg. rheumatic fever or chorea minor, arthritis, endocarditis, glomerulonephritis. Bacterial endocarditis in patients with congenital or rheumatic heart problems before and after minor surgery like removing tonsils, removing teeth, etc. Pneumococcal infections in children with sickle cell anemia. In conditions such as severe pneumonia, empyema, sepsis, pericarditis, endocarditis, meningitis, arthritis and osteomyelitis, treatment in the acute stage should be parenteral.
 
When you should not take Ospen?
Known hypersensitivity to penicillins. In patients with known hypersensitivity to cephalosporins should be considered possible cross alergiya.Peroralno application of penicillin is not indicated in patients with gastrointestinal diseases which cause prolonged diarrhea or vomiting, as the absorption of the drug can be namali.Preporachva Caution in patients with allergic disorders or of asthma.
 
When necessary precautions when adopting Ospen?
Treatment should be discontinued if allergic reactions occur and to apply the usual means such as adrenaline, antihistamines and kortikosteroidi.Pri staphylococcal infections recommends a bacteriological examination. For perioperative prophylaxis in patients receiving penicillin, which require to undergo surgery (removal of tonsils, removing teeth, etc.), For the prevention of rheumatism dose should be udvoi.Pri patients undergoing long-term treatment is recommended full blood count and differential count, and liver function and babretsite.Osobeno attention should be paid to the possibility of the development of resistant strains of microorganisms and fungi with continued dosing. Since infectious mononucleosis is a viral disease, it is not appropriate treatment with antibiotics. If, however, be used, may be increased cases of skin obrivi.Poyavata of severe and persistent diarrhea should arouse suspicion of pseudomembranous colitis caused by antibiotics (watery diarrhea with blood and mucus, to diffuse dull cramping abdominal pain, fever and occasionally painful colic). Since this condition can be life-threatening, the adoption of Ospen should be discontinued immediately and to appoint a specific treatment according to the results of bacteriological testing {eg. oral vancomycin 250 mg four times daily). Adoption of antiperistaltichni products is contraindicated.
 
What other products influence the effect of Ospen or may be affected by product?
As penicillins act only against proliferating microorganisms, Ospen® should not be combined with bacteriostatic antibiotics. Combinations with other antibiotics should be administered only if the expected synergistic or at least additive effect. Doses of participating in the combination drugs must comply with their effective doses (Exception: in case of a synergistic effect of the combination dose of the drug with higher toxicity can be reduced) .It be considered competitive inhibition of elimination when co-administered with anti-inflammatory, anti-rheumatic, antipyretics (particularly indomethacin, phenylbutazone and salicylates in high doses) or probenetsid.Rezorbtsiyata of Ospen reducing its adoption hrana.Podobno with other antibiotics, Ospen® may reduce the efficacy of oral kontratseptivi.Po during treatment Ospen with the results of examination of urine glucose by reducing (non-enzymatic methods), and those of the examination of urobilinogen may be a false positive.
 
What special precautions should be taken during pregnancy and lactation?
So far there are no data showing embryotoxic, teratogenic or mugagenen effects when applying Ospen during pregnancy. It should be borne in mind that Ospen can pass into breast milk.
 
What to be aware when driving, operating machinery or insecure (eg. Climbing stairs)?
No data Ospen influence on the ability to drive or operate machinery.
 
Dosage, method and duration of administration:
Ospen dosage depends on the severity of the infection and is determined only by the doctor!
 
How much and how often you can take Ospen?
Daily doses of Ospen are 50000-100000 IU / kg body weight for adults and 3.5 -4.5 million IU for adolescents and adults. Oral treatment with penicillin is generally recommended that the total daily dose be divided into 2 to 3 doses. In both children and adults the daily dose of Ospen should not be lower than 25 000 iU / kg bw. Adults tolerate slightly daily doses up to 6,000,000 IU.
General dosage regimen
Children over 6 years: 1000000 -1500000 IU (2-3 Ospen 500 tablets) daily. Adolescents (over 40 kg) and adults (over 60 kg): 1 tablet Ospen 1000 every 8 hours (three times daily) .Vazrastni overweight, elderly and pregnant women: 1% Ospen 1000 tablets every 8 hours (three times daily) or one tablet Ospen 1500 every 8 hours (tid). If necessary, the daily dose may be uvelichena.Lechenieto should last 3 days after the disappearance of symptoms. Prevent complications, patients with streptococcal infections should not take this medicine at least 10 days.
 
Special dosage regimen for prophylaxis
Streptococcal disease (eg. Tonsillar angina, scarlet fever): Contact oral administration of therapeutic doses of penicillin for 10 days you can stop the disease. Rheumatism, chorea minor and sickle cell anemia: Children weighing less than 30 kg should take Ospen® 500-1 / 2 tablet every 12 hours (twice a day); children weighing more than 30 kg and adults should take Ospen 500 -1 tablet every 12 hours (twice a day) or Ospen®1000 - 1/2 tablet every 12 hours (twice daily) Prophylaxis against endocarditis (after minor surgical procedures such as removal of the tonsils, removing the teeth, etc.): Children weighing less than 30 kg should take 3 tablets Ospen 500 for about 1 hour before surgery and then 1 tablet 6 hours after surgery. Adolescents weighing over 30 kg and adults should take 6 tablets Ospen 500 (respectively 3 tablets Ospen 1000, or 2 tablets Ospen 1500) about one hour before surgery and then 3 tablets Ospen 500 (respectively 1 1/2 tablets 1 tablet or Ospen®1000 Ospen 1500), 6 hours after surgery.
Dosing in patients with reduced separation
Since Ospen have generally low toxicity is not necessary to reduce the dose in patients with renal impairment or liver. The need to reduce the dosage must be determined individually. In patients with anuria the dose should be decreased or the interval between doses can be extended.
 
When and how you can take Ospen?
The film-coated tablets should be swallowed without chewing with a glass of water one hour before meals.
 
What should I do if Ospen film was adopted in very large amounts (intentional or inadvertent overdose)?
If you swallow large doses of Ospen®, immediately consult your doctor! Symptoms of overdose largely overlapping side effects. Possible gastrointestinal disorders and disorders of fluid and electrolyte balance.
 
What side effects can cause the application of Ospen tablets?
Hypersensitivity reactions
Possible allergic reactions: urticaria, angioneurotic edema, erythema multiforme, exfoliative dermatitis, fever, joint pain or anaphylactic shock with collapse and anaphylactoid reactions (asthma, purpura, gastrointestinal symptoms). They are not common and usually much lighter than those of parenteral administration of penitsilin.Pri patients with mycosis, allergic reactions can be triggered by potentiation of allergenicity of metabolites from skin fungi and penicillin.
Gastrointestinal symptoms
Sometimes there is nausea, diarrhea, vomiting, feeling of fullness in the stomach, stomatitis, glossitis. Diarrhea during treatment should arouse suspicion of pseudomembranous colitis (see also "Special precautions").
haematological abnormalities
Eosinophilia, positive results using the direct method Coombs, hemolytic anemia, leukopenia, thrombocytopenia and agranulocytosis are rare.
 
What measures should be taken in relation to side effects?
If you notice any of these side effects, please inform your doctor. He / she will decide, depending on their weight, what measures predprieme.Molya tell your doctor if you notice any side effects not listed in this leaflet.
Storage Instructions:
Keep out of reach of children! The product should be stored in the original container at a temperature below 25 ° S.Srokat life of the medicinal product is printed on the packaging. Do not use after the expiry date!
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