OSPEXIN 500 mg. 24 tablet

SANDOZ
OSPEXIN 500 mg. 24 tablet
€ 24.00
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What is Ospexin and what it is used
Ospexin contains cephalexin (the group of semisynthetic cephalosporins). This is an antibiotic that kills many different bacteria by inhibiting cell wall biosynthesis. Therefore, it can be used in a wide range of diseases.
Ospeksin is absorbed very well in the body. As the availability of food does not affect significantly the absorption, patients with sensitive stomachs can also accept Ospexin during meals.
Ospexin is well distributed in various tissues of the body.
Ospexin is released in an active form in the urine.

Diseases that can be treated with Ospexin are infections caused by microorganisms sensitive to cephalexin, such as:
Infections of the genitourinary system, incl. prostatitis;
Infections of skin and soft tissues;
Infections of the bones and joints;
Respiratory tract infections;
Infections of the ear, nose or throat;
Dental infections.
After considerable improvement and confirmation that the infecting organism is susceptible, treatment with cephalosporin injections can last Ospexin

2. What you need to know before taking Ospexin
Do not take Ospexin
If you are allergic (hypersensitive) to cephalexin or other cephalosporins or any of the other ingredients of Ospeksin;
Severe systemic infections should be treated from the start with injectable antibiotics.
Warnings and Precautions
Please inform immediately your doctor about any unusual or adverse reaction (see "Undesirable effects").
In the case of pre-sensitized to penicillin is possible increased sensitivity and to tsafaleksin. If you have been diagnosed allergy, particularly to penicillin, you should inform your doctor.
You should tell your doctor if you suffer from increased sensitivity (allergy type hives) or asthma. Treatment should be stopped immediately and consult a doctor in case of symptoms of allergy such as skin rashes, itching, trembling, hives, difficulty breathing, shortness of breath, diarrhea or the occurrence of stomach pains.
If severe and persistent diarrhea, should be considered the probability of inflammation of the colon. In this case it should stop taking Ospeksin and seek medical advice.
Blood samples and liver function tests are recommended for a longer duration of treatment, and functional analysis of the kidney in the presence of renal disease.
During continuous treatment is possible growth of bacteria or fungi, which are not sensitive to cephalexin. In these cases we need to take the necessary measures.
As with other medicines if you are pregnant should not use this product only after consulting your doctor. So you should inform him if you are pregnant or planning a pregnancy.
If you have diabetes, please do not take Ospeksin before discussing it with your doctor.

biochemical reactions
Cephalosporins may cause sometimes false positive results in the test for determining glucose in urine. In these cases, may be used methods based on the glucose oxidase reaction to measure glucose in urine.
Direct test of Coombs (blood test for antibodies against red blood cells) can also give false positive results.
Cephalosporins may affect the determination of ketone bodies in the urine (metabolic products, which are obtained by hard digestion of fat) in the urine.

Other medicines and Ospexin
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
Ospeksin should be administered concomitantly with other antibiotics only explicit recommendation of your doctor as some antibiotics may enhance the action of Ospeksin, while others may weaken it.
Concomitant use with probenecid (a drug that reduces uric acid), may result in increased and prolonged presence of the cephalexin blood.
The combination of cephalosporins with loop diuretics (drugs that increase the excretion of urine) as ethacrynic acid or frusemide, or with other antibiotics damaging kidneys (aminoglycosides, polymyxin B, colistin), may enhance the damaging effects on the kidney.
Concomitant use of cephalosporins and oral anticoagulants may prolong clotting.
Cephalosporins may reduce the effect of oral contraceptives. It is therefore recommended to use additional means of contraception.
Concomitant use of cephalexin and metformin (a medicine for diabetes mellitus), may lead to undesirable high levels of metformin.
Please tell your doctor if you are taking other medicines, and ask which ones are safe to take with Ospexin

Taking Ospexin with food and drink
The film-coated tablets should be swallowed whole with a glass of water. They can be administered on an empty stomach or with food.
HOW TO TAKE OSPEXIN
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.

Unless advised otherwise, the usual dose is:
Adults and adolescents
Daily dose in infections with highly sensitive to cephalexin microorganisms (gram-positive) is 1-4 g.
Daily dose infections with less sensitive to cephalexin micro-organisms (Gram negative) is 4-6 g.
The daily dose can be divided into 2, 3 or 4 individual doses. If necessary, your doctor may prescribe even higher doses.

children
For children under 6 years, the drug comes in liquid form.
The daily dose is 25-50 (up to 100) mg / kg body weight, divided into 2,3 or 4 individual doses.
Children aged 6-10 years: 3 x 1 tablet of 500 mg per day.
Children aged 10-14 years: 3-4 times one tablet of 500 mg per day.
Adolescents and adults should not take a daily dose, in excess of 4 g (= 8 Film-coated tablets Ospeksin 500 mg; = 4 film-coated tablets Ospeksin 1000 mg) without the explicit recommendation of the physician.
In adults, the daily dose should be at least 1 g (= 2 coated tablets Ospeksin or 1 film coated tablet Ospeksin 1000 mg).

Duration of treatment
Your doctor will tell you how long to take Ospeksin. Do not stop treatment without discussing it with your doctor.
Treatment should continue for 2-5 days after symptoms have resolved. Infection with beta-hemolytic streptococci (i.e. angina, scarlet fever) should be treated at least 10 days in order to avoid complications.

Dosage in renal impairment
If renal function is severely reduced, your doctor will lower the dose or increase the time between taking doses. So you should tell your doctor if you suffer from kidney disease.

If you take more than the amount Ospexin
Even accidentally swallow large doses of Ospeksin, it usually does not cause symptoms of poisoning. Overdose can cause stomach / intestinal complaints and disorders of fluid and electrolyte balance.
If you take too many tablets Ospeksin, please contact your doctor.

If you forget to take Ospexin
If you forget to take a tablet, you should do it as soon as you remember. Do not take a double dose to make up the missed dose.

If you stop taking Ospexin
Even if your condition improve or all symptoms have disappeared completely, you should not change or discontinuation of Ospeksin without you consult your doctor to make sure that your condition will not deteriorate or become ill again.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
As with all drugs, this drug may cause side effects, although not everyone gets them.
If you get any side effects, contact your doctor or pharmacist. This includes any possible effects not listed in this leaflet.

The frequency of adverse reactions is defined by:
Very common: (> = 1/10);
Common ((> = 1/100 <1/10);
Uncommon ((> = 1 / 1,000 <1/100);
Rare: ((> = 1/10 000 <1/1000);
Very rare (<1/10 000).
Infections and parasitic diseases
Uncommon: fungal infections of the genital itching around the anus.
Blood and lymphatic system
Rare: changes in the blood (decreased white blood cell count, low platelet count).
Immune System
Common: allergic reactions in prior allergy to penicillin;
Rare: allergic reactions to cephalosporins (generally are lighter in comparison with allergy to penicillin);
Very rare symptoms of acute hypersensitivity with swelling of the skin and mucous membranes (anaphylactic shock) or circulatory collapse.
Allergic symptoms usually disappear after discontinuation of the drug.

Nervous system
Uncommon: headache, weakness, dizziness, confusion.
Dysfunctions of the stomach / intestines
Uncommon: gastrointestinal symptoms (such as diarrhea, nausea, vomiting, loss of appetite), which, however, often be improved even without stopping treatment, inflammation of the oral mucosa. If you develop diarrhea during treatment, care should be taken for possible inflammation of the colon (pseudomembranous colitis).
Disorders of the liver and bile
Very rare transient jaundice and inflammation of the liver;
Transient increases in liver enzymes (SGOT, SGPT).
Skin and subcutaneous
Very rare allergic skin reactions eg. itching, hives or other rashes (erythema multiforme, Stevens-Jones).
Renal and urinary
Very rare violations of renal function (blood in the urine, increased thirst and excessive urine, fatigue) are temporary and disappear after discontinuation of the drug. If these symptoms occur, you should contact your doctor who will decide whether to continue treatment. In rare cases it is found inflammation of the kidneys.
In case of adverse reaction, you should stop taking the drug and seek immediate medical attention.

5. How to store Ospexin
Keep out of reach of children.
Do not use Ospeksin after the expiry date stated on the packaging. The expiry date refers to the last day of that month.
Store at a temperature below 25 ° C.
Store in the original package in order to protect from light and moisture.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and other information
What Ospeksin
Ospexin 500 mg film-coated tablets:
The active substance is cephalexin. Each tablet contains 500 mg of cephalexin.
The other ingredients are macrogol 6000, magnesium stearate, sodium starch glycolate (type A), povidone, lactose, sodium saccharin, peppermint oil, titanium dioxide (E 171), talc, hypromellose.

Ospexin 1000 mg film-coated tablets:
The active substance is cephalexin. Each tablet contains 1000 mg cephalexin.
The other ingredients are macrogol 6000, magnesium stearate, sodium starch glycolate ((type A), povidone, lactose, sodium saccharin, peppermint oil, titanium dioxide (E 171), talc, hypromellose.

Ospexin looks like and contents of the pack
Ospexin 500 mg film-coated tablets:
Oblong, biconvex tablet, scored on both sides, about 7 x 18 mm, white to pale yellowish color. Film-coated tablet can be divided into equal halves.

Ospeksin 1000 mg film-coated tablets:
White to pale yellowish oblong, biconvex tablet, approximately 10 x 21 mm.
Packs containing 12, 24, 100 and 1000 film-coated tablets.
Not all pack sizes may be marketed.
€ 24.00
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