OSPEXIN 250 mg. 12 tablets
Ospexin is an oral broad-spectrum antibiotic from the group of semi-synthetic cephalosporins. In normal concentrations has a bactericidal effect on microorganisms sensitive proliferating, which results in inhibition of cell wall biosynthesis. Ospexin® is also suitable for patients with sensitive stomachs.
What is Ospexin?
Ospexin® be used in mild to moderate infections caused by susceptible microorganisms cephalosporins, eg .:
• Infections of the genitourinary system, incl. prostatitis caused by E. coli, Pr. mirabilis and Kiebsiellae
• Infections of skin and soft tissue caused by Staphylococci and / or Streptococci
• Infections of the bones and joints, incl. osteomyelitis, caused by staphylococci and / or Pr. mirabilis
• Infections of the respiratory tract caused by S. pneumoniae and Group A beta-hemolytic streptococcus
• Otitis media and pharyngitis caused by S. pneumoniae, H. influenzae, staphylococci, streptococci and Neisseria catarrhalis.
• In stomatologiyata- infections caused by staphylococci and / or streptococci.
• Continuation of initial therapy with parenteral cephalosporins.
When you should not take Ospexin?
You should not take Ospexin at:
• confirmed and suspected hypersensitivity to cephalosporins
• in case of hypersensitivity to penicillin, the likelihood of cross allergy is about 5-10%
• severe systemic infections requiring parenteral therapy with cephalosporins should be treated orally during the acute stage
When necessary precautions when taking Ospexin?
In case of pre-penicillin allergy (see. Contraindications) need caution. In patients who develop severe systemic reactions immediately after taking penicillin, cephalosporins should be appointed only after careful medical evaluation. If a hypersensitivity reaction and particularly anaphylactic shock, treatment should be discontinued and the patient should undergo the usual treatment with adrenaline, possible development of resistant organisms or fungi during prolonged therapy. If a secondary infection, should take the necessary merki.Pri event of severe and persistent diarrhea (bloody streaks, mucoid, and watery diarrhea with cramping dull or diffuse abdominal pain, fever and sometimes tenesmus) should be considered pseudomembranous colitis which is connected to the intake of antibiotic and can be life threatening. In such cases, taking Ospexin® should be discontinued immediately and begin therapy on the basis of bacteriological tests (eg. Oral vancomycin 250 mg four times daily). Intestinal peristaltism drugs are contraindicated.
False positive results could show tests for determining glucose in urine and direct test of Coombs (also in newborns whose mothers were taking cephalexin during birth). In such cases, they may be used methods based on the glucose oxidase reaction. Several cases of mild transient increased levels of SGOT and SGPT were found after therapy tsefaleksin.Tsefalosporinite may affect the determination of ketone bodies in urine. Warning to diabetitsite1 scoop of Ospexin 250mg / 5mf suspenztta contains approximately 2.4 g zahar.Koi other products influence the effect of Ospexin® or may be affected by product? Because cephalosporins, such as cephalexin and act only on replicating organisms they should not be combined with bacteriostatic antibiotitsi.Ednovremennata use with probenecid (eg. 0.5 g orally four times daily, which is contraindicated in children under 2 years of age) leads to inhibition of renal eliminirane.Kombiniraneto cephalosporins with loop diuretics (ethacrynic acid, furosemide) or other potentially nephrotoxic antibiotics (aminoglycosides, polymyxin, colistin) may increase the nephrotoxic efekt.Ednovremennoto use of cephalosporins and oral anticoagulants may prolong prothrombin vreme.Tsefalosporinite can reduce the effect of oral contraceptives. It is an interaction between cephalexin and metformin, leading to accumulation of metformin.Kakvi food and drinks you should avoid? Food does not affect the effect of Ospexin. Avoid alcoholic beverages during treatment with Ospexin
What special precautions should be taken during pregnancy and breastfeeding? There is no evidence of teratogenic effects of cephalexin during pregnancy. It should be borne in mind that the cephalexin passes into breast milk.
What to be aware when driving, operating machinery or insecure (eg. Climbing stairs)?
No data Ospexin® influence on the ability to drive or operate machinery.
Dosage, route and duration of administration:
Ospexin dosage depends on the severity of the infection and is determined only by the doctor!
How much and how often you can take Ospexin?
The daily dose for infection by susceptible organisms (Gr +) is 1-4 g. The daily dose for infection with less susceptible organisms (Gr -) is 4-6 g or more, divided into 2, 3 or 4 single dozi.Dnevnata dose should be less than 1g. Usually 3 x 1 tablet 1000 mg.
The daily dose is 25-50 (up to 100) mg / kg, divided into 2, 3 or 4 unit doses. Infants and children up to 6 years of age should not take more than 100mg / kg daily. In older children and adults daily dose may exceed 4 g only if absolutely neobhodimo.Detsa to 1 year 3 x Yz -1 scoop (1 / 2-1 capsule 250mg) Children 1-3 years 3 x 1 scoop (1 capsule 250 mg) Children aged 6-10 years 3 x 1 tablet 500 mg Children aged 10-14 years 3-4 x 1 tablet 500 mgPri mild, uncomplicated urinary tract infections, skin infections and soft tissue and streptococcal pharyngitis, the total daily dosage may be divided into two doses of 12 chasa.Klinichni studies showed that in the treatment of otitis media is a suitable daily dose of 75-100 mg / kg, divided into 4 priema.Lechenieto must continued 2-5 days after symptoms have resolved. Upon infection with beta-hemolytic streptococci is recommended treatment for at least 10 days to prevent relapse.
Dosage in impaired elimination
Standard doses should be reduced in spuchai of znachtelno impaired renal function. Patients on dialysis therapy cephalexin should take 250 mg 1-2 times a day and an additional 500 mg after each dialysis treatment, which is equivalent to a total dose of 1 g on the day of dialysis.
When and how you can take Ospexin?
Ospexin taken orally with or without food. Capsules and coated tablets are taken with a glass voda.Ospexin 250mg / 5ml granules have been developed for pediatric use. The vial is filled with drinking water right up to the mark and immediately shake vigorously. Add more water to the mark and shake again (LOC granules + 37ml water = 60ml suspension 55d granules + 62ml water = 100ml suspension). Shake the vial before each dose.
What should I do if Ospexin® film was adopted in very large amounts (intentional or inadvertent overdose)?
If you swallow large doses of Ospexin, immediately consult your physician Symptoms of overdose Ospexin® largely overlap profile of adverse events, incl. nausea, vomiting, epigastric discomfort, diarrhea and haematuria.
What side effects can cause the application of Ospexin film?
Adverse reactions are relatively rare. So far, no reported serious side effects. Uncommonly arise gastrointestinal upsets such as diarrhea (which in most cases subside spontaneously even more during therapy), also headache * weakness, dizziness, confusion, eosinophilia and neutropenia, stomatitis, vaginal candidiasis, anal pruritus. When diarrhea occurs during treatment, it should discuss the likelihood of the development of pseudomembranous colitis (see. Special precautions). A single occurrence of cases of impaired renal function were reversible. As with some penicillins and cephalosporins, in rare cases can occur cholestatic zhaltenitsa.Alergichni skin reactions manifested as pruritus, urticaria or hives are very rare (erythema multiforme syndrome, Stevens-Johnson). In general allergic reactions to cephalosporins are less prominent than those of the penicillins. They occur more frequently in patients with known allergy to penicillin. Anaphylactic reactions occur very ryadko.Nablyudavani are isolated cases of interstitial nephritis. Allergy symptoms usually resolve after discontinuation.
What measures should be taken in relation to side effects?
If you notice any of these side effects, please inform your doctor. He / she will decide, depending on the severity, what measures to predprieme.Molya tell your doctor if you notice any side effects not listed in this leaflet.
Keep out of reach of children! The product should be stored in the original container at a temperature below 25 ° S.Srokat life of the product is printed on the packaging.
Do not use after the expiry date!