OSPEXIN 250 mg. / 5 ml. 60 ml

SANDOZ
OSPEXIN 250 mg. / 5 ml. 60 ml
€ 8.00
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What is the active substance?
Ospexin 250 mg / 5 tons! A suspension of beads
1 measuring spoon (5 ml) contains 250 mg of cephalexin
Ospexin 250 mg capsules
1 capsule contains 250 mg cephalexin
Ospexin 500 mg film-coated tablets
1 tablet contains 500 mg of cephalexin
Ospexin 1000 mg film-coated tablets
1 film-coated tablet contains 1000 mg of cephalexin
 
What else contains Ospexin?
Ospexin 250mg / 5ml granules for oral suspension; Sodium benzoate, sodium saccharin, sucrose, yellow iron oxide (E 172), simethicone, citric acid, flavors (strawberry powder, raspberry powder, apple powder), guar galactomannan, flavor "tutti frutti "
 
Ospexin 250 capsules; Magnesium stearate, microcrystalline cellulose, indigotine, yellow ferric oxide, titanium dioxide. gelatin
Ospexin 500, 1000 tablets; Macrogol 6000, magnesium stearate, carboxymethyl starch sodium, povidone, lactose, sodium saccharin, peppermint oil, titanium dioxide (E 171), talc, hypromellose
 
 
Formulation and packaging:
Ospexin 250 mg / 5 ml granules, individual packing 60 ml / 100 ml granules for oral suspension
Ospexin 250 mg capsules: individual pack of 12 capsules Ospexin 500 mg / 1000 mg
film-coated tablets: individual pack of 12, 20 film-coated tablets
 
What is Ospexin?
Ospexin is an oral broad-spectrum antibiotic from the group of semi-synthetic cephalosporins. At normal concentrations has a bactericidal effect on microorganisms sensitive proliferating, which results in inhibition of cell wall biosynthesis. Ospexin is also suitable for patients with sensitive stomachs.
 
What is Ospexin?
Ospexin be used in mild to moderate infections caused by susceptible microorganisms cephalosporins, eg .:
• Infections of the genitourinary system, incl. prostatitis caused by E. coli, Pr. mirabilis and Kiebsiellae
• Infections of skin and soft tissue infections caused by Staphylococci and / or Streptococci
• Infections of the bones and joints, incl. osteomyelitis, caused by staphylococci and / or Pr. mirabilis
• Infections of the respiratory tract caused by S. pneumoniae and Group A beta-hemolytic streptococcus
• Otitis media and pharyngitis caused by S. pneumoniae, H. influenzae, staphylococci, streptococci and Neisseria catarrhalis.
• In stomatologiyata- infections caused by staphylococci and / or streptococci.
• Continuation of initial therapy with parenteral cephalosporins.
 
 
When you should not take Ospexin?
You should not take Ospexin at:
• confirmed and suspected hypersensitivity to cephalosporins
• in case of hypersensitivity to penicillin, the probability of cross allergy is about 5-10%
• severe systemic infections requiring parenteral therapy with cephalosporins should be treated orally during the acute stage
 
When necessary precautions when adopting Ospexin?
In the case of pre-penicillin allergy (see. Contraindications) need attention. In patients who develop severe systemic reactions immediately after taking penicillin, cephalosporins should be appointed only after careful medical evaluation. If a hypersensitivity reaction and particularly anaphylactic shock, treatment should be discontinued and the patient should undergo the usual treatment with adrenaline, as is the development of resistant organisms or fungi during prolonged therapy. If a secondary infection, should take the necessary merki.Pri event of severe and persistent diarrhea (bloody streaks, mucoid and watery diarrhea with cramping or dull diffuse abdominal pain, fever and sometimes tenesmus) should be considered pseudomembranous colitis which is associated with the antibiotic and may be life threatening. In such cases, taking Ospexin should be discontinued immediately and begin therapy on the basis of bacteriological tests (eg. Oral vancomycin 250 mg four times daily). Antiperistaltichni drugs are contraindicated.
biochemical reactions
False positive results may show tests for determining glucose in urine and direct test of Coombs (also in newborns whose mothers were taking cephalexin during birth). In such cases, may be used methods based on the glucose oxidase reaction. Several cases of mild transient elevations of SGOT and SGPT were found after therapy tsefaleksin.Tsefalosporinite may affect the determination of ketone bodies in urine. Warning to diabetitsite1 measuring spoon Ospexin® 250mg / 5mf suspenztta contains about 2.4 g zahar.Koi other products influence the effect of Ospexin or may be affected by product? Because cephalosporins such as cephalexin and act only on proliferating microorganisms they should not be combined with bacteriostatic antibiotitsi.Ednovremennata use with probenecid (eg. 0.5 g orally four times daily, which is contraindicated in children under 2 years of age) leads to inhibition of renal eliminirane.Kombiniraneto cephalosporins with loop diuretics (ethacrynic acid, furosemide) or other potentially nephrotoxic antibiotics (aminoglycosides, polymyxin, colistin) may increase the nephrotoxic efekt.Ednovremennoto administration of cephalosporins and oral anticoagulants may prolong prothrombin vreme.Tsefalosporinite can reduce the effect of oral contraceptives. Possible interaction between cephalexin and metformin, leading to accumulation of metformin.Kakvi food and drinks you should avoid? Food does not affect the effect of Ospexin®. Avoid alcoholic beverages during treatment with Ospexin
What special precautions should be taken during pregnancy and breastfeeding? There is no evidence of teratogenic effects of cephalexin during pregnancy. It should be borne in mind that the cephalexin passes into breast milk.
 
What to be aware when driving, operating machinery or insecure (eg. Climbing stairs)?
No data Ospexin influence on the ability to drive or operate machinery.
 
Dosage, method and duration of administration:
Ospexin dosage depends on the severity of the infection and is determined only by the doctor!
 
How much and how often you can take Ospexin?
adults
The daily dose for infection by susceptible organisms (Gr +) e is 1-4. The daily dose for infection with less susceptible organisms (Gr -) is 4-6 g or more, divided into 2, 3 or 4 single dozi.Dnevnata dose should be less than 1g. Usually 3 x 1 tablet of 1000 mg.
 
children
The daily dose is 25-50 (up to 100) mg / kg, divided into 2, 3 or 4 unit doses. Babies and children up to 6 years of age should not take more than 100mg / kg daily. In older children and adults daily dose may exceed 4 g only if absolutely neobhodimo.Detsa 1 year 3 x Yz -1 spoon (1 / 2-1 capsule 250mg) Children 1-3 years 3 x 1 scoop (1 capsule 250 mg) Children aged 6-10 years 3 x 1 tablet 500 mg Children aged 10-14 years 3-4 x 1 tablet 500 mgPri light, uncomplicated urinary tract infections, skin and soft tissue and streptococcal pharyngitis, the total daily dosage may be divided into two doses of 12 chasa.Klinichni studies show that the treatment of otitis media is a suitable daily dose of 75-100 mg / kg, divided into 4 priema.Lechenieto must continued 2-5 days after symptoms have resolved. Upon infection with beta-hemolytic streptococci is recommended treatment for at least 10 days to prevent relapse.
Dosage in impaired elimination
The standard dosage should be reduced in spuchai of znachtelno impaired renal function. Patients on dialysis therapy cephalexin should take 250 mg 1-2 times a day and an additional 500 mg after each dialysis treatment, which is equivalent to a total dose of 1 g on the day of dialysis.
 
When and how you can take Ospexin?
Ospexin be taken orally with or without food. Capsules and coated tablets are taken with a glass voda.Ospexin® 250mg / 5ml granules have been developed for pediatric use. The vial is filled with drinking water right up to the mark and immediately shake vigorously. Add more water to the mark and shake again (LOC granules + 37ml water = 60ml suspension 55d granules + 62ml water = 100ml suspension). Shake the vial before each dose.
 
What should I do if Ospexin film was adopted in very large amounts (intentional or inadvertent overdose)?
If you swallow large doses of Ospexin®, immediately consult your doctor! Symptoms of overdose Ospexin largely overlap profile of adverse events, incl. nausea, vomiting, epigastric discomfort, diarrhea and haematuria.
 
What side effects can cause the application of Ospexin tablets?
Adverse reactions are relatively rare. So far, no reported serious side effects. Uncommonly occur gastrointestinal upsets such as diarrhea (which in most cases resolves spontaneously even more during therapy), also headache * weakness, dizziness, confusion, eosinophilia and neutropenia, stomatitis, vaginal candidiasis, anal pruritus. If diarrhea occurs during treatment, you should discuss the likelihood of development of pseudomembranous colitis (see. Special precautions). Single occurrence of cases of impaired renal function are reversible. As with some penicillins and cephalosporins, in rare cases it may be cholestatic zhaltenitsa.Alergichni skin reactions manifested as pruritus, urticaria or hives are very rare (erythema multiforme syndrome, Stevens-Johnson). In general allergic reactions to cephalosporins are less prominent than those to penicillins. They occur more frequently in patients with known allergy to penicillin. Anaphylactic reactions occur very ryadko.Nablyudavani are isolated cases of interstitial nephritis. Allergy symptoms usually resolve after discontinuation.
 
What measures should be taken in relation to side effects?
If you notice any of these side effects, please inform your doctor. He / she will decide, depending on their weight, what measures predprieme.Molya tell your doctor if you notice any side effects not listed in this leaflet.
 
Storage Instructions:
Keep out of reach of children! The product should be stored in the original container at a temperature below 25 ° S.Srokat life of the medicinal product is printed on the packaging.
Do not use after the expiry date!
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