OSPEXIN 1000 mg. 24 tablets

SANDOZ
OSPEXIN 1000 mg. 24 tablets
€ 29.00
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What is Ospexin and what it is used
Ospexin contains cephalexin (the group of semi-synthetic cephalosporins). This is an antibiotic that kills many different bacteria, by inhibiting the cell wall biosynthesis. Therefore, it can be used in a wide range of diseases.
Ospexin absorbed very well in the body. As the presence of food does not affect significantly the absorption, patients with sensitive stomachs can also accept Ospeksin during meals.
Ospexin is widely distributed in various tissues of the body.
Ospexin was separated into an active form in the urine.

Diseases that can be treated with Ospexin are infections caused by microorganisms sensitive to cephalexin, such as:
Infections of the genitourinary system, incl. Prostatitis;
Infections of skin and soft tissues;
Infections of the bones and joints;
Respiratory tract infections;
Infections of the ear, nose or throat;
Dental infections.
After a significant improvement and confirmation that the infecting organism is susceptible, treatment with cephalosporin injections can continue Ospeksin.

2. What you need to know before taking Ospexin
Do not take Ospexin
If you are allergic (hypersensitive) to cephalexin or other cephalosporins or to any of the ingredients of Ospexin
Severe systemic infections must be treated from the beginning with injectable antibiotics.
Warnings and Precautions
Please inform your doctor immediately about any unusual or adverse reaction (see "Undesirable effects").
In the case of pre-sensitized to penicillin, it is possible to increase sensitivity and tsafaleksin. If you have ever been diagnosed allergy, particularly to penicillin, you should inform your doctor.
You should tell your doctor if you suffer from increased sensitivity (allergy type hives) or asthma. Treatment should be stopped immediately and consult a doctor in case of symptoms of allergy such as skin rashes, itching, trembling, hives, difficulty breathing, shortness of breath, diarrhea or abdominal pain occurs.
If severe and persistent diarrhea, should be considered possibility of inflammation of the colon. In this case it should stop taking Ospexin and seek medical advice.
The blood samples and liver function tests are recommended for a longer duration of treatment, and functional analysis of the kidney in the presence of renal disease.
In long-term treatment is possible growth of bacteria or fungi, which are not sensitive to cephalexin. In these cases, they must take the necessary measures.
As with other medicines, if you are pregnant, you should use this product only after consulting your doctor. Therefore, you must inform him if you are pregnant or planning a pregnancy.
If you have diabetes, please do not take Ospexin before discussing it with your doctor.

Biochemical reactions
Cephalosporins can sometimes cause false positive results in tests for determining glucose in urine. In such cases, they may be used methods based on the glucose oxidase reaction to measure glucose in urine.
The direct test of Coombs (blood test to detect antibodies to red blood cells) can give false positive results.
Cephalosporins may affect the determination of ketone bodies in the urine (metabolic products, which are obtained by decomposition of the hard fat) in the urine.

Other medicines and Ospexin
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
Ospexin should be administered concomitantly with other antibiotics only explicit recommendation of your doctor as some antibiotics may enhance the action of Ospexin, while others may weaken it.
Concomitant use with probenecid (a drug that reduces uric acid) may result in increased and prolonged presence in the blood of cephalexin.
Combining cephalosporins with loop diuretics (drugs that increase the excretion of urine), as ethacrynic acid or furosemide, or other antibiotics, damaging the kidneys (aminoglycosides, polymyxin, colistin) may increase the damaging effects on the kidneys.
Concomitant administration of cephalosporins and oral anticoagulants may prolong clotting.
Cephalosporins may reduce the effect of oral contraceptives. It is therefore recommended to use additional means of contraception.
Concomitant use of cephalexin and metformin (a drug for diabetes mellitus), may lead to undesirable high levels of metformin.
Please tell your doctor if you take other drugs and ask which ones are safe to take with Ospeksin.

Taking Ospexin with food and drink
The film-coated tablets should be swallowed whole with a glass of water. They can be taken on an empty stomach or with food.

Pregnancy and lactation
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, talk to your doctor before taking this medicine.
As with other drugs in pregnancy Ospeksin should be taken only on the recommendation of your doctor. Ospeksin small amounts are excreted in breast milk. There are no known side effects in pregnant women, unborn or newborn children.

Driving and using machines
Ospeksin not affect your ability to drive or operate machinery.

3. HOW TO TAKE Ospexin
Always take this medicine exactly as your doctor tells you. If you're not sure, ask your doctor or pharmacist.

Unless advised otherwise, the usual dose is:
Adults and adolescents
Daily dose in infections with highly sensitive to cephalexin microorganisms (gram-positive) is 1-4 g.
Daily dose infections with less sensitive to cephalexin microorganisms (gram-negative) is 4-6 g.
The daily dose can be divided into 2, 3 or 4 unit doses. If necessary, your doctor may prescribe even higher doses.

Children
For children under 6 years, the drug is available in liquid form.
The daily dose is 25-50 (up to 100) mg / kg body weight, divided into 2,3 or 4 individual doses.
Children aged 6-10 years: 3 times 1 tablet of 500 mg per day.
Children aged 10-14 years: 3-4 times 1 tablet of 500 mg per day.
Adolescents and adults should not take daily doses greater than 4 g (= 8 film-coated tablets Ospeksin 500 mg; = 4 film-coated tablets Ospeksin 1000 mg) without the express recommendation of the physician.
In adults, the daily dose should be at least 1 g (= 2 tablets Ospeksin film 1 or film coated tablet Ospeksin 1000 mg).

Duration of treatment
Your doctor will tell you how long to take Ospeksin. Do not stop treatment without first discussing it with your doctor.
Treatment should continue for 2-5 days after symptoms have resolved. Infection with beta-hemolytic streptococci (ie angina, scarlet fever) should be treated at least 10 days in order to avoid complications.

Dosage in renal impairment
If renal function is severely reduced, your doctor will reduce the dose or increase the time between doses. So you should tell your doctor if you suffer from kidney disease.

If you take more dose Ospexin
Even accidentally swallow large doses of Ospexin, it usually does not cause symptoms of poisoning. Overdose can cause stomach / intestinal complaints and disorders of fluid and electrolyte balance.
If you take too many tablets Ospeksin, please contact your doctor.

If you forget to take Ospexin
If you forget to take a tablet, you should do it as soon as you remember. Do not take a double dose to make up the missed dose.

If you stop taking Ospexin
Even when your condition improve or all symptoms have disappeared completely, you should not change or stop treatment with Ospeksin without you consult your doctor to make sure that your condition will not deteriorate or get sick again.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
If you get any side effects, contact your doctor or pharmacist. This includes all listed in this leaflet.

The incidence of adverse reactions is defined as:
Very common (> = 1/10);
Common: ((> = 1/100, <1/10);
Uncommon ((> = 1/1000, <1/100);
Rare: ((> = 1 / 10,000, <1/1000);
Very rare (<1/10 000).
Infectious and parasitic diseases
Uncommon: fungal infections of the genitals, itching around the anus.
Blood and lymphatic system
Rare: changes in the blood (reduced white blood cell count, low platelets).
Immune system
Common: allergic reactions prior allergy to penicillin;
Rare: allergic reactions to cephalosporins (usually lighter in comparison with allergy to penicillin);
Very rare: hypersensitivity symptoms of acute swelling of the skin and mucous membranes (anaphylactic shock) or circulatory collapse.
Allergic symptoms usually disappear after discontinuation of the drug.

Nervous system disorders
Uncommon: headache, weakness, dizziness, confusion.
Violations of the function of the stomach / intestines
Uncommon: gastrointestinal symptoms (such as diarrhea, nausea, vomiting, loss of appetite), but often improved even without stopping treatment, inflammation of the lining of the mouth. When diarrhea occurs during treatment, care should be taken for possible inflammation of the colon (pseudomembranous colitis).
Liver and biliary
Very rare: transient jaundice and inflammation of the liver;
Transient increase in liver enzymes (SGOT, SGPT).
Skin and subcutaneous
Very rare: allergic skin reactions eg. itching, hives or rash (erythema multiforme, Stevens-Jones).
Renal and urinary tract
Very rare: Deterioration of renal function (blood in urine, increased thirst and increased urination, fatigue) are temporary and disappear after discontinuation of the drug. If these symptoms occur, you should contact your doctor who will decide whether to continue treatment. In rare cases, inflammation of the kidneys found.
In case of adverse reaction, you should stop taking the drug and seek immediate medical attention.

5. How to store Ospexin
Keep out of reach of children.
Do not use Ospeksin after the expiry date stated on the packaging. The expiry date refers to the last day of that month.
Keep at temperatures below 25 ° C.
Store in the original package in order to protect from light and moisture.
Medicines should not be disposed of in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.

6. Contents of the pack and further information
What Ospexin
Ospexin 500 mg film-coated tablets:
The active substance is cephalexin. Each tablet contains 500 mg of cephalexin.
The other ingredients are macrogol 6000, magnesium stearate, sodium starch glycolate (type A), povidone, lactose, sodium saccharin, peppermint oil, titanium dioxide (E 171), talc, hypromellose.

Ospexin 1000 mg film-coated tablets:
The active substance is cephalexin. Each tablet contains 1,000 mg cephalexin.
The other ingredients are macrogol 6000, magnesium stearate, sodium starch glycolate ((type A), povidone, lactose, sodium saccharin, peppermint oil, titanium dioxide (E 171), talc, hypromellose.
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