NEOKALTSIN spray 200 IU 2 ml. 14 doses

NEOKALTSIN spray 200 IU  2 ml. 14 doses
€ 57.00
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NEOKALTSIN Nasal Spray is a synthetic salmon calcitonin, calcitonin-like natural hormone in the body. Calcitonin is a hormone regulating calcium metabolism.



NEOKALTSIN spray 200 IU / 2 ml. 14 doses
 

Pharmaceutical form / content:

Nasal spray 200 IU. / Dose of active substance: Synthetic salmon calcitonin
 

 CONTENTS

 
Active ingredient: Salmon Calcitonin
 
Excipients: Sodium chloride, sodium methylparaben E219, E217 sodium propyl paraben, sodium edetate, 0.1N hydrochloric acid, distilled water.
 

  PHARMACEUTICAL FORM

 
Nasal spray solution.
 
  Content of active substance:
 
1 bottle containing 2 ml at least 14 doses of 200 IU. Synthetic calcitonin.
 

 DESCRIPTION OF THE PACKAGE:

 
NEOKALTSIN Nasal Spray is a colorless, clear solution containing in 5ml glass bottle equipped with a spray pump counting doses. 2 ml vial (14 doses)
 
  Pharmacotherapeutic group
 
Medicine stopping bone loss (osteoporosis).
 

 WHAT YOU SHOULD KNOW ABOUT medication prescribed by your doctor.

 
 General Information
 
NEOKALTSIN Nasal Spray is a synthetic salmon calcitonin, calcitonin-like natural hormone in the body. Calcitonin is a hormone regulating calcium metabolism. It has the opposite effect to that of parathyroid hormone. Calcitonin significantly reduced calcium release from bone in conditions with higher bone mineral metabolism, such as Paget's disease and forms of osteoporosis, characterized by increased bone resorption. Because of reduced renal phosphate reabsorption of sodium and calcium, calcitonin increases the excretion of calcium circulating in high doses. Moreover, calcitonin reduces gastric and pancreatic secretion without affecting gastrointestinal motility. The main objective of kalpitonina are bones. All bone effects of calcitonin developed by osteoclasts, which are located on the receptors for the hormone. Calcitonin reduces the number and activity of osteoclasts. Salmon calcitonin is biologically more active than other types of calcitonin due to the much higher affinity for receptors and a much larger metabolic resistance to fragmentation. After prolonged use of salmon calcitonin for 7-12 months to develop antibodies to the hormone, but it rarely affects clinical effect. As is the case with any other kind of calcitonin and calcitonin salmon when administered to patients with chronic disease Paget, may cause some of them clearance or elevation of serum alkaline phosphatase and urinary hydroxyproline. This phenomenon is probably due to the existence of osteoclasts, which are resistant to the hormone. In such cases, the physician should consider whether treatment should be continued based on the clinical picture.
NEOKALTSIN contain synthetic salmon calcitonin, free of foreign animal proneini.
 
 Indications
 
Treatment of established post-menopausal osteoporosis to reduce the risk of vertebral fractures. It was demonstrated reduction in risk of hip fracture.
 
  Contraindications
 
Hypersensitivity to calcitonin. Application should be avoided in pregnant women or nursing mothers. Calcitonin is contraindicated in patients with hypocalcemia.
 

 SPECIAL WARNINGS AND PRECAUTIONS FOR USE

 General
 
Patients with chronic rhinitis, intranasal administration of calcitonin should be done under medical supervision due to increased bioavailability in such cases. In patients prone to allergic reactions, skin test is recommended prior to initiating therapy. Consult with your doctor.
 
Prerequisites for use
 
Treatment with kaltsitoninovi preparations shown in cases where bone mass is more or less non-conforming to the age and sex standard deviation in the presence of risk factors for osteoporosis and further aggravating factors.
Be considered during use
When starting treatment with salmon calcitonin in rare cases there may be a transient but significant increase in sodium and water excretion.
 

  Adult patients

 
Patients over 65 years old dosage adjustment is necessary by the treating
doctor.
 
Use in pregnant women is not recommended because there is no clinical experience. If you become pregnant during treatment with NEOKALTSIN nasal spray, tell your doctor.
 
 Breastfeeding
 
Do not breast-feed your baby during treatment NEOKALTSIN nasal spray.
 
 Children
 
NEOKALTSIN nasal spray is not recommended for children due to lack of experience.
 
 Effects on ability to drive and use machines
 
Intranasal calcitonin may cause transient dizziness.
 
 Special warnings regarding the excipient
None.
 

 DRUG INTERACTIONS AND OTHER


 

No interaction or incompatibility with other drugs or substances.
 
 Dosage
 
 Note: Before the first use of the nasal spray pump the device must be pressed several times (6 times) successfully when the first dose is reached. The bottle can be stored at room temperature and its content to be used within one month. The recommended dose of intranasal calcitonin for treatment of established post-menopausal osteoporosis is 200 IU a day. The use of intranasal calcitonin is recommended in conjunction with adequate inteyk calcium and vitamin D. Treatment should be administered for a long period of time.
 
  OVERDOSE AND TREATMENT
 
To date, no serious reactions have been reported following overdose.
 

  SIDE EFFECTS

 
Side effects of a general nature (nausea, vomiting, flushing of the face and hands, skin rash) associated with 10% of patients with parenteral use of calcitonin, rarely occur in intranasal form of treatment. Local reactions such as rhinitis, rhinorrhea, and congestion or dryness of the nasal mucosa were observed occasionally.
  

 WHAT TO DO IN CASE OF Missed dose

 
If you need to take medication for a long time and you miss a dose you should take it as soon as possible but no later than 4:00. However, if the next scheduled dose is near, skip the missed dose and continue with treatment as usual.
Do not double doses.
 

  EXPIRATION DATE OF PRODUCT

 
It is marked on the inner and outer packaging. Do not use if the expiration date has passed.
 

  SPECIAL WARNING ON CONSERVATION OF PRODUCT

 
NEOKALTSIN nasal spray should be stored in a refrigerator (2-8 ° C) before use. After opening the bottle can be stored at room temperature and must be used within 30 days.
 

 INFORMATION FOR PROPER USE OF MEDICATION

 
 This medicine has been prescribed by your doctor and is targeted only for your medical problem. It should not be given to others or used for other disease without first consulting your doctor.
  If during the course of treatment appears a problem with medicine, the fastest way, tell your doctor or pharmacist from whom it was purchased.
  If you have any question concerning information on medicine you are taking or need further clarification regarding your medical problem, do not hesitate to request information from your doctor or pharmacist.
  The drug, which is prescribed to you according to the instructions given primate to be effective and safe.
  In the interest of your health and safety, please read all information related to the drug, which is prescribed.
  Do not store medicine in the bathroom, because the heat and humidity can change it and make it bad for your health.
  Do not store medication longer than necessary or after its expiry date.
  For safety reasons keep the drug in children.
 


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