Myconafine table. 250 mg. 14 table
Myconafine table. 250 mg. 14 table
Myconafine WHAT IS AND WHAT IT IS USED
Myconafine is a synthetic product. Its antifungal effect is due to inhibition of enzymes that play a key role in the formation of important substances of fungi. Depending on the concentration, the product can destroy the fungal cell. Myconafine is used to treat:
onychomycosis (nail fungal infection) of the hands and feet caused by dermatophytes;
Tinea capitis (fungal infection of the scalp);
Fungal infections of the skin caused by dermatophytes;
Mycosis of smooth skin - tinea corporis (body), tinea cruris (a calf), tinea pedis (on foot);
Skin infections caused by organisms of the genus Candida (eg Candida albicans).
Unlike local forms of tablets Myconafme product is not effective against Pityriasis versicolor.
WHAT YOU NEED TO KNOW BEFORE TREATMENT WITH Myconafine
Product is used in hypersensitivity to Mikonafin.Pri this medicinal product, please note the following:
The product is used with caution in patients with chronic or active liver disease. Before beginning treatment, it is necessary to evaluate existing liver disease '. In these cases, hepatotoxicity may occur. Patients should be advised to monitor unexplained symptoms of nausea, anorexia, pain in the right upper abdomen honor of or jaundice, dark urine and fatigue.
In patients with pre-existing renal disease (creatinine clearance <50 ml / min) application of the product is not recommended. Treatment should be discontinued at the onset of progressive morbilliform rash.
Rarely can meet and skin reactions like syndrome Stevens-Johnson syndrome and toxic epidermal necrolysis, which also require discontinuation of therapy terapiyata.Pri Myconafme can meet changes in the ocular lens and retina.
In patients with immune deficiency necessary blood counts, particularly when treatment continues for more than six weeks. Upon the occurrence of secondary neutropenia (neutrophil count <1000 kl./m3) treatment product is discontinued and appoint appropriate treatment.
Application Myconafine intake of food and drink
Taking the product is not affected by food and drink.
Before taking any medicines, check with your doctor or farmagtsevtTay the treatment of nail fungus (onychomycosis) may be delayed, treatment is not recommended during pregnancy.
Before taking any medicines, check with your doctor or farmatsevtSled product acceptance he found in breast milk. The ratio between the amount in milk and plasma is 7:1 and therefore not be used during breastfeeding.
Driving and operating machinery
Myconafine not affect your ability to drive or operate machinery.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines soon, even if they have not been prescribed by a doctor
Effect of other medicinal products on terbinafine - separation of terbinafine may be accelerated by drugs that increase metabolism and can be inhibited by drugs that inhibit the metabolism of certain enzymes in the liver (P450 enzyme system). In these cases it may be necessary to adjust dozata.Tsimetidin reduces the release of terbinafine by 33%. Rifampicin enhances separation by 100%.
Effect of terbinafine on other drugs - not affect the excretion of antipyrine and digoksin.Terbinafin may increase the effects of caffeine by 19%. Terbinafine inhibits the metabolism of products mediated by CYP2D6 tricyclic antidepressants, beta-blockers, selective serotonin reuptake inhibitors , antiarrhythmics class 1C products and MAO inhibitors Type B. It increases the clearance of desipramine by 15%. Terbinafine may reduce the effect of tsikrosporin 15%.
HOW TO USE Myconafine
Always Myconafine as your doctor has told you to medical prescription! Apply product in ustata.Vazrastni - 250 mg once daily.
Children over two years, depending on body weight <20 kg - 62,5 mg once daily (half tablet of 125 mg); 20-40 kg - 125 mg once daily,> 40 kg - 250 mg once daily.
The duration of treatment depends on the cause and location of the infection:
In onychomycosis treatment arms still six weeks to three months, and for onychomycosis of the feet - 3 to 6 months, while abnormal nail growth may be needed longer treatment;
Tinea capitis - 4 weeks;
Skin enfektsii - tinea pedis (interdigitalna, plantar type "loafers") - 2 to 6 weeks; tinea corporis, cruris - 2 to 4 weeks;
For smooth skin infections by dermatophytes and Candida skin - 2-4 weeks. Elderly
There is no evidence that these patients require different dosages or the side effects of it are different from those in younger patients. We take into account the possibility of altered renal and hepatic function in these patients.
If you take too much of the drug:
When taking a higher dose than prescribed immediately seek help from a doctor! Data Myconafine overdose is limited. Up to 5 g (20 times the therapeutic dose) were administered without serious adverse reactions. Symptoms usually include nausea, vomiting, abdominal pain, confusion, rash, frequent urination, glavobolie.Preporachva to eliminate product with charcoal and symptomatic treatment
If you forget to Myconafine:
If you forget to take the next dose, take the missed as soon as possible, but do not take both to the next.
POSSIBLE SIDE EFFECTS
Like all medicines, Myconafine can cause adverse reactions reaktsiiNezhelanite are ranked by frequency using the following convention: very common> 1/10, common> 1/100 to <1/10, uncommon> 1/1000do <1/100; Rare> 1/10000 to <1/100S) very rare <1/10000.
No special conditions sahranenie.Da Keep out of reach of children Do not use after the expiry date stated on the package!
Shelf life: 3 (three) years
Myconafine tablets 250 mg Terbinafine
Active substance in one tablet: Terbinafine hydrochloride, eq. a Terbinafine 250 mgPomoshtni ingredients: microcrystalline cellulose, croscarmellose sodium, colloidal silicon dioxide, ???????????????????????????, magnesium stearate.
Myconafme tablets 250 mg x 10 blister AL / PVC-PVdC film 3 blisters (30 tablets) at kutiyaMyconafme tablets 250 mg x 14 in blister AL / PVC-PVdC film first (14 tablets) or 2 blisters (28 tablets) in a box