Metoprolol. 50 mg. 20 tablets

Metoprolol. 50 mg. 20 tablets
€ 9.00
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High blood pressure
- Coronary artery disease
- Hyperkinetic heart syndrome
- tachyarrhythmias
- Intense or long-term treatment after myocardial infarction (prevention of re-infarction)
- Prophylactic migraine.

Metoprolol. 50 mg. 20 tablets

 
 
Active substance : Metoprolol tartrate
Ingredients:
Each tablet contains :
Active substance : metoprolol tartrate, 50 mg;
Other ingredients : croscarmellose sodium 8.625 mg, lactose monohydrate 107.375 mg, polyvinylpyrrolidone 5.000 mg, magnesium stearate 1.500 mg, colloidal anhydrous silica 1.250 mg, talcum 3.750 mg.
 
Pharmacological group and packaging:
Original package with 20 tablets Original package with 50 tablets Original package with 100 tabletkiLekarstvo blocking beta receptors ( beta-blockers )
 
indications:
- High blood pressure
- Coronary artery disease
- Hyperkinetic heart syndrome
- tachyarrhythmias
- Intense or long-term treatment after myocardial infarction (prevention of re-infarction )
- Prophylactic migraine
 
Contraindications :
When you should not use Metoprolol Stada 50 ? Metoprolol Stada 50 should not be used in :
Metoprolol Herds ® 50 should not apply to :
- Second or third degree AB block
- Sinus syndrome
- Disorders of the sino-atrial cardiac impulse conduction ( block CA - ) ,
- Shock,
- Manifest myocardial insufficiency
- Bradycardia ( heart rate below 50 beats per minute before treatment )
- Hypotension (systolic blood pressure less than 90 mm Hg ) ,
- Increased acidity of the blood ( acidosis )
- Advanced forms of interference in the peripheral arterial circulation
- Bronchial hyperactivity (e.g., bronchial asthma ) ,
- Enovremenno treatment with MAO inhibitors ( except MAO -p ) inhibitors ,
- Proven hypersensitivity to Metoprolol Stada 50 or other beta blockers .
Intravenous calcium antagonists of the verapamil or diltiazem type or other antiarrhythmics (such as disopyramide ) are contraindicated in patients treated with Metoprolol Stada 50 ( except under conditions of special surveillance ) .
 
Goat should not use Metoprolol Stada 50 only after consultation with your doctor ?
Under the following conditions Metoprolol Stada 50 should be used only with particular vnimanie.Obsadete your doctor also if you have suffered any of these predi.Metoprolol Stada 50 should be used with caution in :
patients with first degree AB block
- Diabetics with a strong instability of blood glucose concentrations (due to risk of severe hypoglycaemic attack )
- Patients on a strict diet for long periods of time and those exposed to heavy physical exertion (due to risk of severe hypoglycaemic attack ), patients with pheochromocytoma ( hormone - secreting tumors of the medullary portion of the adrenal gland ), Metoprolol Stada 50 in these cases can be used after pre- treatment with alpha -blockers,
- Patients with decreased hepatic function .
In patients with hereditary or already developed psoriasis beta blockers are prescribed only after careful consideration of the anticipated benefits against the potential risks . Beta-blockers may enhance susceptibility to allergens and the severity of anaphylactic reactions. Therefore, they should be used only if they are indispensable in patients with a predisposition to severe hypersensitivity reactions and those receiving specific anti-allergic drugs ( due to risk of excessive anaphylactic reactions) .
 
What you should know if you are pregnant or breastfeeding ?
Metoprolol Stada 50 should be used during pregnancy ( especially during the first 3 months) only under strict indications and rigorous assessment of the expected benefits against the potential risks.
There is evidence to suggest that metoprolol reduced placental perfusion and therefore may impair fetal growth . The use of other beta-blockers was associated with miscarriage , premature birth and fetal death intramatochna . Treatment with metoprolol should be discontinued 48-72 hours before the estimated date of birth, because the drug can cause bradycardia , hypotension and hypoglycemia in the newborn . If this is not possible, the newborn should be monitored closely during the first 48-72 hours after razhdaneto.Metoprololat is excreted in breast milk at levels similar to maternal serum levels . Infants should be monitored for signs of beta- blockade. The amount of metoprolol, taken with milk may be reduced by breast-feeding after 3-4 hours after taking this medicine.
 
Precautions for use :
In case of severe hepatic dysfunction elimination of Metoprolol Stada 50 is delayed and therefore the dose should be namalena.Tay as warning signs of reduced concentration in blood sugar may be masked , need regular blood- sugar. When wearing contact lenses should be taken into account the reduction in the tear fluid . In patients with severe renal failure in some cases have been reported worsening of renal function during treatment with beta-blockers . Therefore, treatment with Metoprolol Stada 50 must be accompanied by careful monitoring of renal function. Interruption or change of treatment is only allowed as medical advice . If treatment with Metoprolol Stada 50 should be interrupted or discontinued after prolonged use , it should be done slowly because abrupt withdrawal can lead to cardiac ischemia by provoking angina pectoris ( angina ) , heart attack or high blood pressure.
 
What you should consider when driving , operating machinery or working on unstable platforms ?
Patients taking this drug should be under constant medical supervision. Individually different reactions can alter attention to such an extent as to impair the ability to actively participate in road traffic, operating machinery or working on unstable platforms . This applies more prominently at the beginning of treatment , an increase in dose or abrupt change of treatment , and the concomitant use of alcohol.
 
Drug interactions:
Which drugs interfere with the action of Metoprolol Stada 50 or vice versa ?
Co-administration of Metoprolol Stada 50 with insulin or oral antidiabetic agents , the effect of the latter can be enhanced by mask or dilute the symptoms of low blood sugar concentration (hypoglycemia ) , rapid heartbeat (tachycardia) , especially tremor . Hence the need for regular monitoring of blood zahar.Ednovremennata use of Metoprolol Stada 50 and tricyclic antidepressants , barbiturates, phenothiazines, glyceryl , diuretics, vasodilators , and other antihypertensive drugs can cause a severe drop in blood pressure.
Concomitant Metoprolol Stada 50 with calcium channel blockers such as nifedipine can cause rapid drop in blood pressure and, in isolated cases - the development of heart failure.
Cardiodepressant action Metoprolol Stada 50 and that of antiarrhythmic drugs may be superimposed .
Patients taking concomitant Metoprolol Stada 50 and calcium channel blockers of the verapamil or diltiatsema atniaritmichni or other means (such as disopyramide ) should be carefully monitored because there is a risk of hypotension , bradycardia or heart rhythm disorders .
 
Note:
Intravenous treatment with calcium channel blockers of the verapamil or diltiatsema atniaritmichni and other intravenous drugs ( such as disopyramide ) is contraindicated in patients treated with Metoprolol Stada 50 (except for mode intensive care ) .
Co-administration of Metoprolol Stada 50 and cardiac glycosides , reserpine , alpha -methyldopa , clonidine, guanfacine or clonidine can cause severe reductions in cardiac rhythm or conduction delays cardiac impulse . Venzapnoto interruption of the use of clonidine in both treatment Metoprolol Stada 50 may lead to an excessive increase in blood pressure . Therefore , when clonidine was administered simultaneously with Metoprolol Stada 50 should not be interrupted until the reception of metoprolol was not stopped a few days earlier . Only then clonidine mine is progressively reduced to discontinuation ( see prescribing information for clonidine ) .
Concurrent use of Metoprolol Stada 50 with noradrenaline , adrenaline or other sympathomimetics (eg, constituting the preparations cough , nasal drops or eye ) can cause a significant increase in blood pressure. Patients treated with 50 Metoprolol Stada can react less dose of epinephrine commonly used in the treatment of allergic reactions.
MAOIs must be used concurrently with Metoprolol Stada 50 because of the risk of an excessive increase of the blood pressure.
Indomethacin and rifampicin may reduce the antihypertensive effect of Metoprolol Stada 50.Tsimetidinat may increase the plasma concentration of Metoprolol Stada 50 . Metoprololat may reduce the excretion of other drugs (eg, lidocaine ) . Concurrent use of Metoprolol Stada 50 and narcotics / analgesics may cause very low blood pressure. Negative inotropic effects of these drugs can be naslozhat.Nerv but muscular blockade with peripheral muscle relaxants (eg, succinylcholine halide, tubocurarine) can be enhanced by inhibition of beta- receptors of Metoprolol Stada 50 . If Metoprolol Stada 50 can not be stopped before procedures requiring general anesthesia or prior use of peripheral muscle relaxants, anasteziologyt must be informed of its use.
Note that this information applies to recently used drugs.
 
Dose , route and duration of administration :
The instructions below apply if the doctor has prescribed otherwise. Please spazvaytegi for effective and safe treatment with Metoprolol Stada 50 .
How many tablets Metoprolol Stada 50 and how often should I apply ?
The dosage should be individually adjusted, mainly as the result of treatment and should not be ' changed without medical advice .
If the doctor advises otherwise , it is recommended that the following dosage:
- Hypertension :
1 tablet of Metoprolol Stada 50 once or twice a day or 1-2 tablets daily (equivalent to 50-100 mg daily metoprolol tartrate ) . If necessary , the daily dose may be increased to 2 tablets twice daily ( equivalent to 200 mg metoprolol tartrate per day).
- Coronary artery disease :
1 tablet of Metoprolol Stada 50 once or twice a day or 1-2 tablets daily (equivalent to 50-100 mg daily metoprolol tartrate ) . If necessary , the daily dose may be increased to 2 tablets twice daily ( equivalent to 200 mg metoprolol tartrate per day).
- Hilerkinetichen heart syndrome:
1 tablet of Metoprolol Stada 50 once or twice a day or 1-2 tablets daily (equivalent to 50-100 mg daily metoprolol tartrate ) . If necessary , the daily dose may be increased when the blood pressure monitor on 2 tablets twice daily ( equivalent to 200 mg metoprolol tartrate per day).
 
tachyarrhythmias :
2 tablets Metoprolol Stada 50 once or twice daily (equivalent to 100-200 mg metoprolol tartrate ) .
- Intense or long-term treatment during or after a heart attack :
Metoprolol Stada 50 is used in patients who are not contraindicated treatment with beta-blockers .
a) Intensive Care
For severe myocardial infarction , treatment should begin immediately after admission to the hospital with 5 mg intravenous metoprolol tartrate in continuous monitoring of ECG and blood pressure. Patients who suffer well first bolus injection is given at intervals of 2 minutes an additional 2 single doses of 5 mg intravenously metoprolol tartrate for a total dose of 15 mg.Pri patients who tolerate well total intravenous dose (15 mg metoprolol tartrate ) during the next 48 hours is given every 6 hours 1 tablet , starting 15 min after the last inzhektsiya.Pri patients who tolerate less than 15 mg metoprolol tartrate by the intravenous , oral therapy should be started gently with 1x25 mg metoprolol tartrate .
b) Maintenance dose
Thereafter, patients should receive a maintenance dose of 2 tablets Metoprolol Stada 50 2 times a day. In the event that the heart rate and / or blood pressure is reduced so that the required therapeutic intervention or in the case of other complications , treatment with Metoprolol Stada 50 must be stopped immediately .
- Preventive migraine :
2 tablets Metoprolol Stada 50 once or twice daily (equivalent to 100-200 mg daily metoprolol tartrate ) . Patients with severely impaired liver function , eliminating Metoprolol Stada 50 is delayed and therefore the dosage should be reduced.
 
How and when should I take Metoprolol Stada 50 ?
The tablets should be swallowed whole with plenty of water after a meal. Unless otherwise specified , a single dose of Metoprolol Stada 50 must be taken in the morning , and two-time - morning and evening.
How to share Metoprolol Stada 50 ?
Put the tablet Metoprolol Stada 50 on a hard surface with the groove up . Press your thumb on top and the tablet will break into two equal pieces.
 
How long should I take Metoprolol Stada 50 ?
The duration of treatment should be determined by your doctor.
 
Overdose and other errors in the application :
What should you do in case of an overdose ( intentional or unintentional ) of Metoprolol Stada 50 ?
In case of overdose , please contact your doctor immediately . Depending on overdose may cause severe hypotension , bradycardia, to the point of cardiac arrest, heart failure and cardiogenic shock. Other signs of overdose may include difficulty breathing , bronchospasm , vomiting, clouding of consciousness , and in isolated cases - generalized seizures .
In case of overdose or very slow heart beat or hypotension , treatment with Metoprolol Stada 50 should be stopped .
 
What should you do if you take more than the prescribed dose or you miss a dose ?
Continue with Metoprolol Stada 50 as prescribed and do not take a double dose next priem.Kakvo need to do if you interrupt or stop treatment prematurely ? Treatment with Metoprolol Stada 50 may be interrupted or suspended only under medical instruction. Abrupt stopping can cause myocardial ischemia by exacerbation of angina ( angina ) , myocardial infarction , or an increase in blood pressure .
 
Undesirable effects :
Especially at the beginning of treatment there were isolated reports of disturbances in the central nervous system such as fatigue, dizziness , depression, dizziness , confusion , headache, sweating , nightmares or abnormal increased activity of dreaming , sleep disturbances and hallucinations . These side effects are usually mild and transient.
In rare cases have been reported gastrointestinal symptoms , including nausea , vomiting , abdominal pain, constipation or diarrhea, which also have transitional harakter.Ponyakoga may experience dyspnea exertional, and rarely - bronchospasm (see Contraindications ) . Has single reports of paresthesia and a feeling of cooling of the extremities and less muscle weakness or muscle cramps.
There have been isolated reports of aggravated symptoms in patients with intermittent claudication and impaired peripheral circulation ( including patients with Raynaud's syndrome ) . There was rarely reported lower blood pressure such as when rising from a lying position (orthostatic hypotension ), sometimes with loss of consciousness, syncope , palpitations , bradycardia, atrioventricular conduction disturbances , exacerbation of myocardial failure with peripheral edema and / or dyspnea on exertion .
In patients with angina pectoris may not be excluded that the deterioration of these attacks , observed in individual cases .
Patients with bronchospastic disease ( especially those with obstructive airway disease ) can obtain apnea, because this drug increases airway resistance .
There have been rare reports of dry mouth, conjunctivitis or reduced tear secretion (to be considered in patients wearing contact lenses) and isolated reports of disturbances in zrenieto.Metoprolol Stada 50 may mask the symptoms of tireotoksikoza.Imalo is rarely reported " unlock " latent diabetes or worsening of the symptoms one. Patients complying with the absolute diet long period of time , and those subjected to great physical stress can be obtained if use hypoglycaemia whilst Metoprolol Stada 50 . The warning symptoms of hypoglycaemia (especially tachycardia and tremor ) may be maskirani.V isolated cases there have been reports of decreased libido and impotence . There were also isolated reports of hair loss, hearing impairment and tinnitus , weight gain, personality changes (eg, emotional lability, short term memory loss ), thrombocytopenia (reduced platelet count ) or leukopenia ( decrease in white blood cells ) , allergic rhinitis or Alzheimer 's Peyroni.Imalo occasionally allergic skin reactions ( erythema , pruritus , exanthema , photosensitivity ) . treatment Metoprolol Stada 50 may be associated with disruption of the lipid metabolism . While total cholesterol was generally normal , HDL- cholesterol was reduced and plasma triglycerides were povisheni.Prodalzhitelnata use of Metoprolol Stada 50 in isolated cases has been associated with arthropathy (affecting one or more joints) .
There have been isolated reports of elevations of serum transaminases (GOT, GPT) or hepatitis.
 
Cautionary Notes :
Beta-blockers in isolated cases may provoke or worsen psoriasis or induce psoriasiform skin rashes, beta-blockers may enhance susceptibility to allergens and the severity of anaphylactic reactions. Patients with a history of severe hypersensitivity reactions and those of specific immunotherapy / desensitization can get excessively strong anaphylactic reactions. If you get any side effects not listed in this leaflet, make sure your doctor or pharmacist.
 
Shelf life and storage instructions :
The deadline date is printed on the box. Do not use after this date. Store at a temperature not higher than +25 ° C. Keep all medicines out of reach of children!
 
 
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