Methergin 125 mg. 30 tablets
Metilergometrinat is a semisynthetic derivative of the natural ergot ergometrine. Methergin drug exerts its effects by causing muscle contraction of the uterus.
Methergin used in obstetrics for:
• active management of the third stage of labor (as a means of stimulating the release of the placenta and reduce blood loss);
• improve the tone of the uterus and control of bleeding during and after the third stage of labor, cesarean birth or after abortion;
• treatment of incomplete involution of the uterus, lochia-audiometry (enlargement of the uterus as a result of the retention of secretions, blood or tissue debris, which can not be eliminated)
and bleeding after birth.
Methergin should not be used for the induction or augmentation of labor!
2. BEFORE YOU TAKE Methergin
Do not use Methergin:
• If you are allergic / a (you are hypersensitive) to Methergin, ergot alkaloids or to any of the excipients listed at the beginning of this leaflet.
If you think you may be allergic, ask your doctor.
• If you are pregnant.
• If you are in the first or second stage of labor (before displaying the baby's head).
• In the presence of very high blood pressure.
• If you suffer from a condition known as pre-eclampsia or eclampsia.
• If you have occlusive vascular disease, including coronary heart disease.
• If you have an infection (eg. "Milk fever").
If you suffer from any of these conditions, tell your doctor and do not take Methergin.
Caution with Methergin:
• If you have mild or moderate hypertension.
• If you have impaired kidney or liver function.
If any of these conditions apply to you, tell your doctor before taking Methergin.
Methergin and elderly Methergin is not intended for use in the elderly.
Methergin and children
Methergin is not intended for use in children.
Methergin should not be used during pregnancy. Your doctor will discuss with you the potential risks of taking Methergin during pregnancy.
Methergin passes into breast milk and is not recommended during lactation.
Your doctor will discuss with you the potential risks of taking Methergin during lactation.
Driving and using machines
Methergin may cause dizziness and convulsions, and therefore you must be especially careful when driving or operating machinery, especially at the beginning of treatment.
Important information about some of the ingredients of Methergin
Methergin coated tablets contain lactose. If your doctor has told you that you have an intolerance to some sugars (eg. Lactose), contact your doctor for advice before taking Methergin.
Can you use Methergin if you are taking other medicines?
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines. Remember medicines obtained without a prescription.
It is particularly important to tell your doctor if you are taking any of the following medications:
If you are being treated for infection with drugs ordered macrolide antibiotics such as erythromycin, clarithromycin, troleandomycin.
• If you are treated by HIV / AIDS drug ritonavir. nelfinavir. indinavir or delavirdine.
• If you are being treated for a fungal infection like ketoconazole, itraconazole or voriconazole.
• If you are treated with drugs with vasoconstrictor activity, including medicines for migraine such as sumatriptan or containing ergot alkaloids such as ergotamine. Methergin may enhance their effect.
• If you are treated with bromocriptine (a medicine used to suppress lactation). Simultaneous administration with Methergin.
Some anesthetics can reduce the effectiveness of Methergin.
3. HOW TO USE Methergin?
Carefully follow your doctor's instructions. Do not exceed your recommended dose. Take your medicine exactly as directed by your doctor. Do not change the dosage and discontinuation of therapy without consulting your doctor.
What you get?
Treatment of incomplete involution of uterus lohiometra and bleeding postpartum: 0.125 to 0.250 mg orally (1 or 2 tablets) three times a day.
If you forget to take Methergin
If you miss a dose, do not take and do not double the next dose and continue your regular dosing schedule.
If you take more Methergin than necessary
Symptoms of overdose are: nausea; vomiting; hypertension; low blood pressure; tingling, numbness and pain in the extremities; respiratory depression; seizures; loss of consciousness.
If you accidentally take too much Methergin, immediately contact your doctor. You may need medical attention.
4. POSSIBLE SIDE EFFECTS
Methergin can cause some side effects in some people.
Some uncommon side effects (less common than 1 in every 100 people, but more often than 1 in 1000) may be serious.
Immediately contact your doctor:
• If you experience seizures (convulsions).
• If you have chest pain.
Some very rare effects (less than 1 in every 10,000 people) could be serious:
Tell your doctor immediately:
• If you have unexplained shortness of breath, "cutting" chest pain or clouding of consciousness.
• If you have signs of allergy such as a rapid fall in blood pressure, flushing and / or swelling.
• If you have numbness, tingling in the fingers or toes and pale or cold hands or feet.
• If you have hallucinations.
• If you have swelling in a certain place, redness, pain due to clot in a vein (thrombophlebitis symptoms).
Other side effects
Common (less than 1 in 10 people but more than 1 in every 100 people): headache, elevated blood pressure, skin reactions, abdominal pain.
Uncommon (less than 1 in every 100 people, but more than 1 in 1,000 people): dizziness, low blood pressure, nausea, vomiting, profuse sweating.
Rare (less than 1 in 1,000 people): slow heart rate, heart rate, irregular heartbeat.
Very rare (less than 1 in 10,000 people): ringing in the ears, nasal congestion, diarrhea, muscle cramps.
If any of these effects so bad to you, tell your doctor.
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE Methergin
• Methergin coated tablets: Store below 30 ° C.
• Do not use Methergin after the expiry date stated on the packaging.
• Store in original container.
• Keep away from children.
• 5 years from date of manufacture.