Metamizole amp. 500 mg. Ml. 2 ml. 10 amp

Metamizole amp. 500 mg.  Ml. 2 ml. 10 amp
€ 19.00
Add to Cart
Metamizole Sodium is a product of the group Pyrazolone short-and temperature decreasing analgesic effect.
 



Metamizole amp. 500 mg. / Ml. 2 ml. 10 amp
 
INGREDIENTS:
1 ml of the solution contains as active substance 500 mg Metamizole sodium and excipient Water for Injections to 1 ml.
 
 
PHARMACEUTICAL FORM II CONTENTS ;
Solution for injection in dark vials or no J 2 ml in a blister.
 
 
 
ACTION:
Metamizole Sodium is a product of the group Pyrazolone short- and temperature decreasing analgesic effect.
 
 
INDICATION :
For transient response of acute moderate to moderately strong pain (post surgery pain spasms in smooth muscle of the urinary and biliary) . To ss only with a prescription.
 
 
CONTRAINDICATIONS :
Allergies, including to other pyrazolone drugs and prostaglandpnovata synthesis inhibitors (such as aspirin , indomethacin, Voltaren , piroxicam ), disturbance in hematopoiesis ( granulocytopenia and thrombocytopenia ), a genetically determined absence of the specific enzyme glucose-6- phosphate dehydrogenase deficiency, fulminant hepatic porphyria . Use in hematologic patients is only in exceptional cases, strictly controlling the performance of the hematopoietic and accurate assessment of the potential risk. Not recommended drug administration during the first and last trimester of pregnancy and during lactation , and children up to 13 years.
 
 
SPECIAL PRECAUTIONS FOR USE:
Parenteral administration in children and patients with impaired renal function should be avoided. Intravenous administration of the product is only in exceptional cases because of the risk of severe allergic reactions, including anaphylactic shock and collapse. Injection under the skin should be avoided as local irritation and risk of developing abscesses . In patients with increased risk of anaphylaxis should have a careful assessment of the risk / benefit . Parenteral administration of Metamizole can cause hipotnniya , especially in patients with dehydration starting circulatory collapse politravma etc. . It is possible to red coloration of the urine as a result of the separation of the metabolite rubazonova acid .
 
 
 
Interactions :
With concomitant administration of Metamisole sodium with other nonsteroidal anti-inflammatory drugs may increase the risk of allergies. When co-administered with medicinal products containing gold salts , and other bone marrow suppressants products increases the risk of agranulocytosis . Metamisole sodium may reduce the excretion of methotrexate and increase plasma levels and toxicity . Alcohol potentiates the analgesic effect of Metamizole Sodium . Synergistic and combine successfully with peripheral M - holinolititsi , aminophenazine , quinine , codeine . It can be combined with atropine Buscolysin other antispasmodics . Chloramphenicol and other myelotoxic drugs potentiate the risk of side effects from the haematopoietic . Its effects are potentiated by tricyclic antidepressants, oral contraceptives medicines alopurpnol due to enzyme inhibition and delay of its biotransformation . As a result of hepatic enzyme induction Metamizole Sodium reduces the activity of coumarin anticoagulants . Lowered plasma levels of cyclosporine . Tempidon enhance and prolong the effect of Metamizole Sodium . Not alter the effect of uterokinetichnite and uterotonic drugs.
 
 
SPECIAL WARNINGS FOR USE IN PREGNANCY , BREASTFEEDING AND CHILDREN :
Not recommended drug administration during pregnancy , especially in the first and last trimester and during lactation , and in children up to 13 years.
 
 
 
EFFECTS ON THE ABILITY TO DRIVE AND USE MACHINES :
No evidence of adverse effect on alertness and reflexes due to the medicinal product can be administered to drivers and handlers l ! Ashina . As a precaution , patients should be advised of the possible occurrence of hipotiniya and related symptoms.
 
 
HOW TO USE AND DOSAGE:
Parenteral ( for intramuscular administration).
Upon intramuscular administration to adult patients, the maximum single dose is 500 mg, the maximum daily dose is 1.5 g. Not recommended for long term use ( more than a few days) , unless explicitly prescription.
Parenteral administration in children up to 13 years should be avoided.
 
 
 
ACTION OF OVERDOSE :
Overdose occur epileptiform convulsions , decreased urine output , cyanosis ( bluish ) , collapse, menieropodobni phenomena , nausea , abdominal pain . There is no specific antidote . Treatment is symptomatic . The major metabolite ( 4 -N-methylaminoantipyrin) can be removed by hemodialysis , hemofiltration or plasma filtration.
 
 
 
SIDE EFFECTS :
At higher dosages are possible allergic skin reactions , hypersensitivity syndrome Layell and Stevens-Johnson, anaphylactic shock , leucopenia , agranulocytosis (reduction in white blood cells and the impairment of hematopoiesis ) and thrombocytopenia. Upon intramuscular injection incorrectly there is a risk of developing abscesses . Possible hypotension , acute worsening of renal function , followed by proteinuria, oliguria and anuria . In some cases, you may develop and acute interstitial nephritis .
 
 
 
Storage:
At temperatures below 25 ° C in a dry, protected from light . Then I kept out of reach of children!
 
 
SHELF LIFE :
Three (3 ) years.
The product should not be used after the expiry date shown on the packaging.

€ 19.00
Add to Cart
Close