MILGAMMA 100 mg. 30 tablets
Milgamma 100 is a medicine for the treatment of neuropathies.
Milgamma 100 is used for the treatment of diseases of the nervous system (neurological diseases) in which is established a deficiency of vitamin B1 and vitamin B6.
2. BEFORE YOU TAKE MILGAMMA 100
Do not take milgamma 100
if you are hypersensitive (allergic) to vitamin B1 (thiamine), benfotiamine, vitamin B6 (pyridoxine hydrochloride) or any of the other ingredients of milgamma 100.
Milgamma 100 is contraindicated in pregnancy and lactation.
Take special care with milgamma 100
Children and the elderly
There is no information on the application of milgamma 100 in children and the elderly.
The medicinal product should not be taken by children as there is no sufficient therapeutic experience in this age group.
Taking milgamma 100 with other medicinal products
Please tell your doctor or pharmacist if you are taking / using or have recently taken / apply other medicines, including medicines obtained without a prescription.
Concomitant use of hydralazine, isoniazid / INH /, D-penicillamine, cycloserine, alcohol and long-term use of estrogen-containing oral contraceptives may cause vitamin B6 deficiency. Thiamine is deactivated by 5-fluorouracil as 5-fluorouracil competitively inhibits the phosphorylation of thiamine to thiamine pyrophosphate. Therapeutic doses of vitamin B6 may reduce the effects of L-dopa.
Please note that these figures apply to medicinal products whose reception has ended recently.
Taking milgamma 100 with food and drink
It is not necessary to implement special measures for use of milgamma 100 with food and drinks.
Pregnancy and lactation
Milgamma 100 can be used during pregnancy only if it is proved that the patient suffers from deficiency of vitamins B1 and B6. Therefore you can take milgamma 100 only if your doctor considers it absolutely necessary. The recommended daily dose of vitamin B1 in pregnancy is 1,4 - 1,6 mg, vitamin B6 and for - from 2,4 to 2,6 mg. Taking more than the recommended daily dose has not been proven as safe. Therefore milgamma 100 is contraindicated in pregnancy.
Milgamma 100 can be used during lactation only if it is proven that the patient suffers from deficiency of vitamins B1 and B6. Therefore you can take milgamma 100 only if your doctor considers it absolutely necessary.
The recommended daily dose of vitamin B1 during lactation is 1,4 - 1,6 mg, a vitamin B6 - from 2.4 to 2,6 mg. Taking more than the recommended daily dose has not been proven as safe. Vitamins B1 and B6 pass into breast milk, such as high doses of vitamin B6 may hinder his production. Therefore, during pregnancy and lactation milgamma 100 is contraindicated.
Driving and using machines
No special precautions when driving or operating machinery.
Important notice on some components of milgamma 100:
This product contains sucrose (sugar). Please consult your doctor if you know that you are intolerant to certain sugars.
Milgamma 100 may cause neuropathy, in the event that it is administered for a period longer than 6 months.
3. HOW TO TAKE MILGAMMA 100
The following information milgamma 100 you can take into consideration only if your doctor prescribes something different. Please follow the instructions and recommendations of your doctor! Otherwise milgamma 100 will not have the desired therapeutic effect.
It is advisable to take only one tablet milgamma 100 to H times a day. The tablets should be swallowed with sufficient fluid at any time of day.
After a course of treatment no longer than four weeks the doctor must decide whether to continue treatment with high dose vitamin B6 and vitamin B1. (3x1 coated tablets daily). If necessary, the dose should be reduced to 1 tablet daily to reduce the risk of vitamin B6-related neuropathy.
If you take more dose milgamma 100
When symptoms occur, seek medical attention.
If you forget to take milgamma 100
Do not take a double dose to make up for a forgotten tablet.
Accept milgamma 100 at the usual time, both now and in the future try to agree to be regular.
If you stop taking milgamma 100
Upon discontinuation of treatment, you jeopardize its success! If you experience unacceptable side effects, talk to your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, milgamma 100 can cause side effects, although they do not necessarily occur in any patient.
In assessing the adverse reactions following data are used for the frequency of their occurrence:
Very common: more than 1 in 10 treated;
Common: less than 1 in 10 but more than 1 in 100 people;
Uncommon: less than 1 in 100 but more than 1 in 1,000;
Rare: less than 1 in 1,000 but more than 1 in 10,000 treated;
Rare: less than 1 per 10,000 treated, incl. single cases;
Adverse reactions symptoms (to be given) and countermeasures
Very rare: Isolated cases of hypersensitivity reactions (urticaria, exanthema), including shock.
Nervous system disorders
With unknown frequency: Continuous use over a period longer than six months can cause peripheral sensory neuropathy.
Very rare: isolated cases of gastro-intestinal dysfunction, eg. nausea or other symptoms have been reported during clinical trials. Cause - effect relationship with vitamin B1 and / or B6 and possible Dose-dependency are not yet firmly established.
If any of the side effects gets serious, or you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
At systemic hypersensitivity reactions take place appropriate emergency measures. If adverse effects, please contact your doctor.
The active substances are benfotiamine and pyridoxine hydrochloride.
5. HOW TO STORE MILGAMMA 100
Keep out of reach of children!
The expiry date is printed on the blister and carton. The expiry date refers to the last day of that month.
Do not use this medicine after the expiry of the said period of life!
Do not store above 25 ° C, in place protected from light.
6. ADDITIONAL INFORMATION
What milgamma 100
Each coated tablet contains:
Benfotiamine (fat-soluble derivative of vitamin B1) - 100 mg;
Pyridoxine hydrochloride (Vitamin B6 - 100 mg.
Highly dispersed silicon dioxide, microcrystalline cellulose, croscarmellose sodium, povidone, talc, long chain glycerides, shellac, sucrose, calcium carbonate, gum arabic, corn starch, titanium dioxide (E 171), macrogol 6000, glycerol 85%, polysorbate 80, montan glycol wax .
Free of gluten does not contain lactose.
Looks milgamma 100 and contents of the pack
Original packs of 30, 60 and 100 coated tablets.
For the information of our patients:
Milgamma 100 coated tablets contain: benfotiamine and pyridoxine hydrochloride.
Benfotiamine are fat-soluble form of vitamin B1 and a modified molecule of this vitamin. Digested (absorbed is) in the body several times better than the same amount of conventional water-soluble vitamin B1. After absorption in the intestine, in the body benfotiamine is converted to the active substance - vitamin B1.
Pyridoxine hydrochloride is indicated as vitamin B6.
Both vitamins are essential micronutrient.
If the body does not introduce sufficient amounts over time can occur phenomena of deficiency, such as neurological systemic diseases. These diseases are generally accompanied by functional disorders in the metabolism of neurons. The consequences can include: pain and sensory disorders, primarily in the soles of the feet.