MEXIA 10 mg. 28 tablets

SANDOZ
MEXIA 10 mg. 28 tablets
€ 49.00
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What Mexia and what it is used
How does Mexia
Mexia belongs to a group of medicines known as anti-dementia drugs.
Memory loss in Alzheimer's disease is due to disturbances in the signals of messages in the brain. The brain contains so-called. N-methyl-D-aspartate (NMDA) receptors involved in the transmission of nerve signals, which are important for learning and memory. Mexia belongs to a group of medicines called antagonists, NMDA-receptors. Mexia acts on these NMDA-receptors improving the transmission of nerve signals and the memory.

What is Mexia
Mexia is used to treat patients with moderately severe to severe Alzheimer's disease.

2. What you need to know before taking Mexia
Do not take Mexia:
if you are allergic to memantine hydrochloride or any of the other ingredients of this medicine (listed in section 6).
Warnings and Precautions
Talk to your doctor or pharmacist before taking Mex if:
have a history of epileptic seizures;
You have recently experienced a myocardial infarction (heart attack) or if you suffer from congestive heart failure or uncontrolled hypertension (high blood pressure).
In these situations the treatment should be carefully supervised, and the clinical utility of MEXIA be regularly reassessed by your doctor.
If you suffer from renal impairment (kidney problems), your doctor should closely monitor your kidney function and if necessary adapt the memantine doses accordingly.
The use of medicinal products amantadine (for the treatment of Parkinson's disease), ketamine (a substance generally used as an anesthetic), dextromethorphan (generally used to treat cough) and other NMDA-antagonists should be avoided.

Children and adolescents
Mex is not recommended to treat children and adolescents aged under 18 years.

Other medicines and Mex
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
In particular, Mex may alter the effects of these drugs and may need your doctor may adjust their dose:
amantadine, ketamine, dextramethorphan;
dantrolene, baclofen;
cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine;
hydrochlorothiazide (or any combination with hydrochlorothiazide)
anticholinergic agents (substances that are generally used to treat movement disorders or intestinal cramps);
anticonvulsants (substances that are used to prevent or treat seizures);
barbiturates (substances that are commonly used to induce sleep);
dopaminergic agonists (substances such as L-dopa, bromocriptine);
neuroleptics (substances that are used to treat psychiatric disorders);
oral anticoagulants.
If you go into hospital, let your doctor that you are taking Mex.

Mexia food and drinks
Tell your doctor if you have recently changed or intend to change your diet substantially (eg from normal diet to strict vegetarian diet) or if you suffer from renal tubular acidosis (RTA, an excess of acid-forming substances in the blood due to renal dysfunction (malfunction kidney)) or severe infections of the urinary tract (structure that carries urine), as it may be necessary to adjust the dose of the drug.

Pregnancy and lactation
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.
Memantine is not recommended for use in pregnant women.
Women taking Mex, should not breastfeed.

Driving and using machines
Your doctor will tell you whether your illness allows you to safely drive or operate machinery.
Moreover, Mex may change your reactivity, making driving or operating machinery.

Important information about some of the ingredients of Mex
Mex contains lactose monohydrate. If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this product.

3. How to take Mexia
Mex starting package is only used when initiating treatment with Mex.
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.

dosage
The recommended treatment dose of 20 mg per day is achieved by gradually increasing the dose of Mex during the first 3 weeks of treatment. The treatment scheme is also listed on the package for treatment initiation. Take one tablet once a day.

Week 1 (day 1-7):
Take one tablet mexyl 5 mg once a day (white to off-white, oval-oblong) for 7 days.

Week 2 (day 8-14):
Take one tablet mexyl 10 mg once a day (pale yellow to yellow, oval shaped) for 7 days.

Week 3 (day 15-21):
Take one tablet mexyl 15 mg once daily (orange, oval-oblong) for 7 days.

Week 4 (day 22-28):
Take one tablet mexyl 20 mg once a day (pale red, oval-oblong) for 7 days.
week 1 5 mg tablet
week 2
10 mg tablet
week 3
15 mg tablet
week 4
20 mg tablet once a day
maintenance dose
The recommended maintenance dose is 20 mg once daily.
Regarding the duration of treatment, please consult your doctor.

Dosage in patients with impaired renal function
If you have impaired kidney function, your doctor will decide what dose is appropriate for your condition. In this case, the physician should monitor your kidney function at regular intervals.

Method of administration
Mex should be administered orally once a day. To benefit from your medicine, you should take it regularly every day at the same time of day. The tablets should be swallowed with some water. The tablets can be taken with or without food.

Duration of treatment
Taking Mex continues until there is an effect. Your doctor should assess your treatment on a regular basis.

If you take more than the amount of Mexia
In general, taking too much MEXIA should not harm you. It may experience increased symptoms as described in section 4. "Possible side effects".
If you accept Mexia at a dose several times higher than prescribed, contact your doctor or get medical advice, as you may need medical attention.

If you forget to take Mexia
If you forget to take your dose Mex, wait and take the next dose at the usual time.
Do not take a double dose to make up the missed dose.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Usually, the observed side effects are mild to moderate.

Common (affects 1 to 10 of 100 patients):
Headache, sleepiness, constipation, dizziness, shortness of breath, high blood pressure and drug hypersensitivity.
Uncommon (affects 1 to 10 of 1000 patients):
Tiredness, fungal infections, confusion, hallucinations, vomiting, abnormal gait, heart failure and venous blood clotting (thrombosis / embolism).
Very rare (affects less than 1 in 10,000 patients):
Seizures.
Not known (from the available data can not be estimated frequency):
Inflammation of the pancreas and psychotic reactions.
Alzheimer's disease is associated with depression, suicidal thoughts and suicide attempts. These events have been reported in patients treated with memantine.

5. How to store Mexia
Keep out of reach of children.
Store in the original container.
Do not store above 25 ° C.
Do not use this medicine after the expiry date stated on the carton and blister after "EXP". The expiry date refers to the last day of that month.
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