MENKART 100 mg. 25 mg. 100 tablets
Menkart is used to treat the symptoms of the disease, Parkinson.
MENKART 100 mg. / 25 mg. 100 tablets
What is MENKART and what it is used?
Levodopa is an anti-Parkinsonian agent, a decarboxylase inhibitor benserazide is, assisting levodopa so as to improve its operation.
Menkart is used to treat the symptoms of the disease, Parkinson.
2 Before you take MENKART
Do not take Menkart:
if you are allergic (hypersensitive) to levodopa, benserazide or any of the other ingredients of this medicine;
if you have hyperthyroidism (overactive thyroid), very fast heartbeat or pheochromocytoma (tumor of the adrenal glands that causes hypertension);
if you have severe hormonal, heart, liver or KIDNEY DISEASE;
if you suffer from psychosis (a mental state characterized by a personality disorder and loss of contact with reality);
if you have narrow-angle glaucoma (high pressure in the eye);
if taking reserpine or monoamine oxidase inhibitors (MAO inhibitors, e. tranylcypromine), used to treat high blood pressure and depressed mood. Moreover, do not take Menkart if you are taking an MAO inhibitor in the past 12 hours.
Take special care with Menkart:
Tell your doctor before taking this medicine:
if you have ever had a heart attack or heart problems;
if you have orthostatic hypotension (low blood pressure associated with changes in body position, which can cause dizziness or vertigo);
if you have had peptic or intestinal ulcer;
if you have ever had seizures (convulsions);
If you have ever suffered from osteomalacia (bone disease similar to rickets);
if you have a wide-angle glaucoma (high pressure in the eye);
if you have diabetes. You'll need to control your blood sugar levels more often and may need your doctor to adjust the dose of your diabetes medicine;
if you are under 25 years of age, as experience in this age is limited;
if you have an operation.
During treatment with levodopa / benserazide may appear depressed and suicidal thoughts, although they may be due to HIV disease. If you feel depressed while on treatment, consult your doctor.
Patients treated with dopamine agonists for Alzheimer's Parkinson, including levodopa have been reported pathological gambling, increased sexual desire and sexual activity. If you have similar experiences, you should inform your doctor.
You should continue as you have been told by your doctor. A sudden stop can cause potentially life-threatening adverse reactions (see section 3 below "If you stop taking MENKART").
Your doctor may decide to conduct some tests that require taking blood or urine samples at regular intervals of time, to control heart rate and blood pressure.
Taking other medicines
Consult your doctor if you are taking any of the following:
Monoamine oxidase inhibitors (MAOI) (used to treat depression): the combination of these drugs MENKART can cause severe increase in blood pressure. This can happen if you are taking MAO inhibitors in the last two weeks (see "Do not take MENKART" above);
Drugs that could enhance or diminish the effects of MENKART:
Other drugs for the treatment of Parkinson's disease such as bromocriptine, amantadine, triheksipeptidil or entacapone;
Ferric sulfate (used for the treatment of iron deficiency);
Metoclopramide (used in the treatment of eating disorders);
Drugs belonging to a group called opioids such as codeine, oxycodone, morphine or tramadol (a pain);
Medicines for high blood pressure, which contain reserpine (see "Do not take MENKART 'above);
Neuroleptics such as haloperidol, flupentixol or chlorpromazine (used for the treatment of psychiatric disorders including excessive anxiety or schizophrenia, nausea, vomiting and hiccup);
Medicines for high blood pressure: Your blood pressure will be very low. You may need your doctor to adjust the dose of your medicine for high blood pressure;
Drugs belonging to the group known as sympathomimetic agents such as clonidine or salbutamol should not be taken at the same time with MENKART: the effect of these drugs could be enhanced. You may need your doctor to adjust the dose of your treatment with sympathomimetic.
MENKART may interfere with test results of certain substances in the blood.
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
Taking Menkart with food and drink:
Adoption of Menkart food rich in proteins can weaken its effect.
Whenever possible, take Menkart 30 minutes to 1 hour before meals.
Pregnancy and lactation:
You should not take Menkart if you are pregnant. If you are of childbearing age must use a reliable method of birth control.
You should not breastfeed while being treated with Menkart.
Ask your doctor or pharmacist before taking any medicine.
Driving and using machines:
Levodopa is associated with somnolence and very rarely with severe daytime sleepiness and sudden sleep onset episodes. This can happen without warning symptoms. If you get these symptoms, you should tell your doctor. Should refrain from driving or where impaired state of alertness may put yourself or others in a state of high risk of serious injury, while these episodes have resolved.
3 How to take MENKART?
Always take MENKART exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist.
100 mg / 25 mg: MENKART treatment usually starts with a low dose, e. half tablet, four times a day.
200 mg / 50 mg: treatment MENKART usually starts with a low dose, e. quarter tablets two to four times daily.
100 mg / 25 mg: After three to seven days, your doctor may decide to increase your dose to one tablet every three to seven days to achieve adequate control of your symptoms.
200 mg / 50 mg: After three to seven days, your doctor may decide to increase your dose to half a tablet every three to seven days to achieve adequate control of your symptoms.
The maximum dosage is generally not more than:
100 mg / 25 mg: eight tablets per day.
200 mg / 50 mg: four tablets daily.
The daily dose should be spread over the day in a number of smaller doses. The size of individual doses and the frequency of which is taken to be adapted so as to best meet the needs of each individual patient.
To manifest fully the effect of your medicine may take several weeks.
If you have previously received levodopa alone or with another decarboxylase inhibitor, you should stop taking it at least twelve hours before you start taking MENKART.
Whenever possible, you should take MENKART 30 minutes to 1 hour before meals. You should swallow the tablets with some liquid, without chewing.
If you take more than you should MENKART
If you (or someone else) are absorbed many tablets at once, or you think a child has swallowed any of the tablets, immediately call the nearest hospital or your doctor. Please bring this leaflet and any remaining tablets and the container with you to know the hospital or doctor which tablets were consumed.
Overdose may cause worsening of your symptoms, as well as confusion, hallucinations and sleep disorders. Rarely occur nausea and vomiting (being sick) and irregular heart rhythm.
If you forget to take MENKART
Do not take a double dose to make up for a missed dose. Pick your dose as usual, although the process may return to receive some of the problems caused by the disease of Parkinson.
If you stop taking MENKART
Your doctor will determine when you should stop taking MENKART. Typically, the drug is taken for a long time, as it replaces dopamine, which is not produced in sufficient quantity in patients with Alzheimer's Parkinson.
If you want to stop taking MENKART, you should tell your doctor. Although rare, sudden discontinuation can cause potentially life-threatening side effects, including a condition called neuroleptic malignant syndrome, which includes a very strong increase in body temperature, muscle cramps and physiological changes akinetic crises (inability to move). To reduce the likelihood of its occurrence, the doctor will advise you to stop.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 Possible side effects:
Like all medicines, MENKART may cause side effects, although not everybody gets them.
Adverse reactions listed below were reported in the indicated approximate frequency:
Common (affects no-less than one in 10 patients, but in low frequently than 1 in 100):
variations in treatment response as "freezing" (sudden onset of difficulty in movement), "end of dose" (return of symptoms prior to the next dose) and "on-off" phenomenon (sudden changes in the condition of periods of good control of the symptoms, to a period in which no control);
irregular or abnormal volitional movements (dyskinesia);
Rare (acc least one of the 1000 patients, but more than one in 10, 000):
hallucinations, particularly in elderly patients;
disorientation to time, mainly in the elderly;
allergic skin reactions such as rash and itching.
Very rare (affects less than one in 10,000 patients):
transient blood disorders (low white or red blood cells or platelets);
elevated levels of substances called transaminases and alkaline phosphatase in the blood;
excitement, especially in the elderly;
anxiety, mainly in the elderly;
sleep disorders in the elderly;
delusions, mainly in the elderly;
loss of appetite;
very strong daytime sleepiness;
sudden onset of sleep;
changes in blood pressure, which can be improved with reduction of the dose;
loss or change in taste sensation;
discoloration of urine, usually in red.
manifestation of hidden psychosis (a mental condition that is characterized by changes in personality and loss of contact with reality);
bleeding in the digestive system;
elevated levels of certain substances in the blood such as uric acid or urea;
redness and sweating.
At a later stage of treatment, and in most cases, after the medication has been administered for many years may experience uncontrolled, abnormal movements arms, legs, face or tongue or unevenness of the response to treatment. They can disappear if changed daily dose or divided into smaller, but more frequent doses administered throughout the day.
These side effects typically occur at the beginning of treatment and usually can be controlled by adopting MENKART food or drink and slowly increasing the dose.
In patients receiving dopamine agonists for the treatment of Alzheimer's Parkinson, including levodopa, especially in higher doses has been reported pathological gambling, increased libido and sexual behavior, which are generally reversible upon dose reduction or discontinuation .
If any of the side effects gets serious, or if you notice other effects not listed in this leaflet, please tell your doctor or pharmacist.
5 How to store MENKART
Keep out of reach of children.
MENKART not use after the expiry date stated on the bottle and carton. The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6 Further information:
The active substances are levodopa and benserazide.
One tablet contains 100 mg of levodopa and 25 mg of benserazide (as hydrochloride).
One tablet contains 200 mg of levodopa and 50 mg of benserazide (as hydrochloride).
The other ingredients are mannitol, microcrystalline cellulose, pregelatinized corn starch, calcium hydrogen phosphate anhydrous, povidone K-25, crospovidone, colloidal silica anhydrous, iron oxide red (E172), and magnesium stearate.
MENKART looks like and contents of the pack
MENKART tablets 100 mg / 25 mg tablets are round, biconvex, light red speckled tablets with two intersecting score lines on both sides. They can be divided into equal quarters and are available in white opaque polyethylene bottles TE / SF screw caps with dehumidifier containing 20, 30, 50, 60 and 100 tablets.
MENKART tablets 200 mg / 50 mg are round, flat, bright red speckled tablets with faceted edges, with two intersecting score lines on both sides and marked B and L in two sections. They can be divided into equal quarters and are available in white, opaque polyethylene bottles TE / SF screw cap, a dehumidifier containing 20 Ç0, 50, 60 and 100 tablets.
He all pack sizes may be marketed.