MEMANTINE ACCORD 10 mg. 28 tablets

ACCORD
MEMANTINE ACCORD 10 mg. 28 tablets
€ 39.00
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What Memantine Accord and what it is used
How does Memantine Accord:
Memantine Accord belongs to a group of medicines known as anti-dementia drugs. Memory loss in Alzheimer's disease is due to disturbances in the signal message in the brain. The brain contains so. Called. N-methyl-D-aspartate (NMDA) receptors involved in the transmission of nerve signals, which are important for learning and memory.
Memantine Accord belongs to a group of medicines called antagonists, NMDA-receptors. Memantine Accord acts on these NMDA-receptors improving the transmission of nerve signals and the memory.

What is Memantine Accord:
Memantine Accord is used to treat patients with moderate to severe Alzheimer's disease.

2. What you need to know before taking Memantine Accord
Do not take Memantine Accord:
If you are allergic to memantinov hydrochloride or any of the other ingredients of this medicine (listed in section 6).
Warnings and Precautions
Talk to your doctor or pharmacist before taking Memantine Accord:
If you have a history of epileptic seizures;
If you have recently experienced a myocardial infarction (heart attack) or if you suffer from congestive heart failure or uncontrolled hypertension (high blood pressure).
In these situations the treatment should be carefully supervised, and the clinical benefit of Memantine Accord be assessed by your doctor.
If you suffer from renal impairment (kidney problems), your doctor should closely monitor your kidney function and if necessary adapt the memantine doses accordingly.
Adopting the same time of medicinal products amantadine (for the treatment of Parkinson's disease), ketamine (a substance generally used as an anesthetic), dextromethorphan (generally used to treat cough) and other NMDA-antagonists should be avoided.

Children and adolescents
Memantine Accord is not recommended for children and adolescents under 18 years.

Other medicines and Memantine Accord
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.

In particular, Memantine Accord may alter the effects of these drugs and may need your doctor may adjust their dose:
amantadine, ketamine, dextramethorphan;
dantrolene, baclofen;
cimetidine, ranitidine, procainamide, quinidine, quinine, nicotine;
hydrochlorothiazide (or any combination with hydrochlorothiazide)
anticholinergic agents (substances that are generally used to treat movement disorders or intestinal cramps);
anticonvulsants (substances that are used to prevent or treat seizures);
barbiturates (substances that are commonly used to induce sleep);
dopaminergic agonists (substances such as L-dopa, bromocriptine);
neuroleptics (substances that are used to treat psychiatric disorders);
oral anticoagulants.
If you go into hospital, let your doctor that you are taking Memantine Accord.

Memantine Accord with food and drink
Tell your doctor if you have recently changed or intend to change your diet substantially (eg from normal diet to strict vegetarian diet) or if you suffer from renal tubular acidosis (RTA), an excess of acid-forming substances in the blood due to renal dysfunction ( poor kidney function)) or severe infections of the urinary system (urinary tract) as may be necessary to adjust the dose of the drug.

Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine.
Tell your doctor if you are pregnant or planning to become pregnant. Memantine is not recommended for use in pregnant women.
Women taking Memantine Accord, should not breastfeed.

Driving and using machines
The doctor will tell you whether your illness allows you to safely drive or operate machinery.
Moreover, Memantine Accord may change your reactivity, making driving or operating machinery.

Memantine Accord contains lactose.
This medicinal product contains lactose. If your doctor has told you that you have an intolerance to some sugars, please contact your doctor before taking this medicine for advice.

3. How to take Memantine Accord
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.

dosage
The recommended dose Memantine Accord for adults and elderly patients is 20 mg once daily. To reduce the risk of side effects this dose is achieved gradually by the following daily schedule:
Week 1: half a tablet of 10 mg;
Week 2: one tablet of 10 mg;
Week 3: one and a half tablet of 10 mg;
Week 4 and beyond: 2 tablets of 10 mg once a day.
The usual starting dose is half a tablet once daily (1 x 5 mg) in the first week. This is increased to one tablet once a day (1 x 10 mg) in the second week and to 1 and a half tablet once a day (1 x 15 mg) in the third week. From the fourth week on, the usual dose is 2 tablets once daily (1 x 20 mg).

In patients with impaired renal function
If you have impaired kidney function, your doctor will decide what dose is appropriate for your condition. In this case, the physician should monitor your kidney function at regular intervals.

application
Memantine Accord should be administered orally once daily. To benefit from your medicine, you should take it regularly every day at the same time of day. The tablets should be swallowed with some water. The tablets can be taken with or without food.

Duration of treatment
Taking Memantine Accord long as it is of benefit to you. Your doctor should assess your treatment on a regular basis.

If you take more dose Memantine Accord
In general, taking too much Memantine Accord should not harm you. It may experience increased symptoms as described in section 4. "Possible side effects".
If you take Memantine Accord at a dose several times higher than prescribed, contact your doctor or get medical advice, as you may need medical attention.

If you forget to take Memantine Accord
If you find that you forgot to take your dose Memantine Accord, wait and take your next dose at the usual time.
Do not take a double dose to make up the missed dose.

If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Usually, the observed side effects are mild to moderate.

Common (may affect up to 1 in 10 people):
Headache, sleepiness, constipation, elevated liver function tests, dizziness, balance disorder, shortness of breath, high blood pressure and drug hypersensitivity.
Uncommon (may affect up to 1 in 100 people):
Tiredness, fungal infections, confusion, hallucinations, vomiting, abnormal gait, heart failure and venous blood clotting (thrombosis / embolism).
Very rare (may affect up to 1 in 10,000 people):
Seizures.
Not known (from the available data can not be estimated frequency):
Inflammation of the pancreas, liver inflammation and psychotic reactions.
Alzheimer's disease is associated with depression, suicidal thoughts and suicide attempts. These events have been reported in patients treated with memantine.

If you get any side effects, contact your doctor or pharmacist. This includes any possible side effects not listed in this leaflet.

Adverse event reporting
If you get any side effects, contact your doctor or pharmacist. This includes any possible effects not listed in this leaflet. You can also report side effects directly via the national reporting system. By reporting side effects, you can do your bit for getting more information on the safety of this medicine.

5. How to store Memantine Accord
Keep out of reach of children.
Do not use Memantine Accord after the expiry date stated on the carton and blister after "EXP". The expiry date refers to the last day of that month.
This medicinal product does not require any special storage conditions.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer use. These measures will help to protect the environment.

6. Contents of the pack and other information
What Memantine Accord
The active substance is memantinov hydrochloride. Each tablet contains 10 mg of memantinov hydrochloride equivalent to 8,31 mg memantine.
The other ingredients are lactose monohydrate, microcrystalline cellulose, silica, colloidal anhydrous, crospovidone, magnesium stearate - in the tablet core; hypromellose, polysorbate 80, macrogol 400, titanium dioxide (E 171) - in the tablet coating.

Memantine Accord looks like and contents of the pack
The film-coated tablets Memantine Accord are white, oblong wrapped scored, debossed with "MT" of one divided by the score line and "10" on the other hand, divided by the score line. The tablet can be divided into two equal doses.
The film-coated tablets Memantine Accord is available in blister packs (PVC / PE / PVDC-aluminum blister) of 14 tablets, 28 tablets, 30 tablets, 42 tablets, 50 tablets, 56 tablets, 98 tablets, 100 tablets and 112 tablets.
Not all pack sizes may be marketed.
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