MELBEK FORT 15 mg. 30 tablets
Each tablet contains 15 Melbek Fort meloxicam.Pomoshtni mg Excipients: Crospovidone, Povidone K-30, Avicel PH 102, sodium citrate, lactose / anhydrous / Aerosil 200, magnesium stearate.
Melbek Fort can be found in packs of 10 or 30 tablets.
How does Melbek Fort?
Melbek Fort is a nonsteroidal anti-inflammatory drug (NSAID) which has the following proven anti-inflammatory, analgesic and antipyretic properties. Melbek Fort shows anti-inflammatory properties in all standard models of inflammation. Due to its specificity of action Melbek Fort expressed no side effects on the stomach and kidneys typical of other NSAIDs. In clinical studies, it is clearly demonstrated that the incidence of side effects from the gastrointestinal tract in patients taking Melbek Fort in normal doses were much lower compared to those using other NSAIDs.
Oral meloxicam is well absorbed (89%). The rate of absorption is not affected by food intake. The concentration of the drug directly correlates with the quantity taken by mouth (e.g., 15 mg) .Stabilna plasma concentrations are achieved for 3 to 5 days of treatment. More than 99% of Melbek Fort, which is located in the blood binds to plasma beltatsi.Sposobnostta of Melbek Fort penetration in synovial fluid is good; concentration there is approximately half that in plazmata.Golyama part of Melbek Fort metabolised and less than 5% of the daily dose is excreted as metabolites in the faeces unchanged. Unchanged metabolites are excreted in the minimum amount by urinata.Vremeto half-life of meloxicam is about 30 hours. Pharmacokinetic parameters are unchanged in patients with liver failure and mild to moderate renal insufficiency.
What cure Melbek Fort? Melbek Fort is a non-steroidal anti-inflammatory agent that is indicated for the symptomatic treatment of:
* Rheumatoid arthritis
* Painful osteoarthritis (arthrosis, degenerative joint disease)
* Ankylosing spondylitis (ankylosing spondylitis)
When not to apply Melbek Fort?
Melbek Fort is contraindicated in patients who are svrahchustvitelni to meloxicam or other components of the preparation. Cross-reaction may occur in patients who are known to be sensitive to acetylsalicylate (aspirin) and other NSAIDs. Melbek Fort should not be administered to patients with more asthma attacks, nasal polyps, swelling that can affect the face, extremities, lips, tongue and throat (angioedema) or urticarial reactions to any type of NSAID, and in the following cases:
* Active peptic ulcer
* Severe hepatic insufficiency
Severe renal failure without dialysis
* Children and adolescents under the age of 15
* Pregnant and nursing mothers
Bleeding, regardless of what type
Special warnings and precautions during treatment with Melbek Fort? Melbek Fort should be used with caution in some cases, so before you start treatment with Melbek Fort inform your doctor if you suffer from:
* Hronosmilatelni disorders (esophagitis, gastritis, gastric ulcer or duodenal)
* Heart failure or high blood pressure
* Heart, liver or kidney disease
* Treatment with diuretics (water resources) or recent surgery
* Spend asthma: in some cases it is possible occurrence of allergic reactions to aspirin or other means from the group of NSAIDs (which include the Melbek Fort)
* If you are being treated with anti-clotting (anticoagulants)
It is imperative to discontinue therapy and contact your doctor immediately in the following cases:
* When gastrointestinal bleeding (from mouth or stools, black discoloration of feces) * Signs suggestive of hypersensitivity to the drug and in particular asthma attack, sudden swelling of the face or throat, blistering
Use in pregnant and lactating mothers
This medicine is not recommended for use during pregnancy. Its use during lactation should be avoided. Consult your doctor before use of medicines during pregnancy or karmene.Lekarstvata of the NSAIDs may adversely affect the fertility of women who currently use aspire to conception.
What interactions occur between Melbek Fort and other medications are being treated?
Tell your doctor if you are taking or have recently taking other medicines, even those obtained without a prescription. It is particularly important to tell your doctor if you are taking oral anticoagulants (anti-clotting drugs), other NSAIDs, high doses of aspirin, heparin (given by injection), lithium, high-dose methotrexate, ticlopidine, contraception 'water treatment chemical, pharmaceutical products lowering blood pressure, cholestyramine, cyclosporine, oral antidiabetic agents.
Melbek Fort affect you ability to drive and use machines?
Melbek Fort negative influence on psychosomatic status and alertness. In individual patients it can cause dizziness and drowsiness. In such cases it is recommended to perform activities associated with active attention and driving.
How to take Melbek Fort?
The dosage and duration of treatment is determined by the treating you lekar.Preporachitelnite doses are:
Rheumatoid arthritis: 15 mg / day. Depending on the response the dose can be reduced to 7.5 mg / day
Osteoarthritis: 7.5 mg / day. If necessary, the dose may be increased to 15 mg / day
Ankylosing spondylitis: 15 mg / denPri patients at high risk of side effects: treatment should always begin with 7.5 mg / den.Pri patients with highly advanced renal failure: the daily dose should not exceed 7.5 mg / den.Pri pain conditions the dose is adjusted by a physician, the maximum daily dose of Melbek Fort was 15 mg / den.Tay the daily dose in children is not specified, this drug is administered only to vazrastni.Tabletkite be taken with water or other liquid during meals.
While taking Melbek Fort
Since there is no specific antidote, if you make a mistake and take more than the recommended dose, immediately contact your doctor.
What side effects may cause Melbek Fort?
Rarely these side effects that are probably related to the administration of meloxicam:
Gastrointestinal: More frequent than 1%: dyspepsia (indigestion), nausea, vomiting, abdominal pain, constipation, diarrhea, flatulence (bloating) .Mezhdu 0.1 and 1%: transitory abnormalities in liver function parameters, eructation, oesophagitis (inflammation of the esophagus), stomach ulcer or duodenal ulcer, hidden or detectable macroscopic gastrointestinal kravotecheniya.Po less than 0.1%: gastrointestinal perforation, colitis, hepatitis, gastritis.
Blood and hematopoietic organs: More often than 1%: anemiya.Mezhdu 0.1 and 1%, changes in blood counts, including a differential count of the white blood cells, leukopenia (reduction in white blood cell count) and thrombocytopenia ( reducing the number of blood platelets). Coadministration with drugs affecting the bone marrow, in particular methotrexate, a predisposing factor to the development of cytopenia.
Skin: More frequent than 1%: itchy skin or ligavitsite.Mezhdu 0.1 and 1%: stomatitis (inflammation of the lining of the mouth), urticaria (hives) .Po less than 0.1%: photosensitivity.
Respiratory System: Less than 0.1%: in some individuals after administration of NSAIDs, including aspirin, and meloxicam was observed for acute asthma.
Central nervous system: More frequent than 1%: dizziness, glavobolie.Mezhdu 0.1 and 1%: vertigo, tinnitus, sanlivost.Po less than 0.1%: confusion and disorientation, changes in mood.
Cardiovascular system: More often than 1%: edema (swelling) .Mezhdu 0.1 and 1%: elevated blood pressure, heart rate, flushing.
Urogenital System: Between 0.1 and 1%: abnormal renal function parameters (increased serum creatinine and / or serum urea).
Visual narusheniyaPo less than 0.1%: conjunctivitis, visual disturbances including blurred zrenie.Reaktsii hypersensitivity (allergic) Less than 0.1%: angioedema (sudden swelling of the face or throat) and hypersensitivity reactions fast type, including anaphylactoid / anaphylactic reactions (type of allergic immediate reactions).