MEKORLONG. 100 mg. 30 tablets
MEKORLONG. 100 mg. 30 tablets
MEKORLONG WHAT IS AND WHAT IT IS USED
Mekorlong is a medicine that belongs to the group of so-called beta-blockers.
It is used for treatment of :
High blood pressure (hypertension ), i angina ( chest pain caused by a condition in \ which the blood supply to the heart is reduced or blocked) .
Abnormal heart rhythm ( arrhythmia) .
Chronic heart failure ( a condition in which the heart can not pump enough blood to meet the body's needs ) as adjunct to other therapy in heart failure.
Functional disorders of the heart ( palpitations) . It is used for the prevention of:
Emergence of a new heart attack (myocardial infarction) and other disorders of the heart after a heart attack survivor . Migraine .
2 . BEFORE YOU USE MEKORLONG
Do not use Mekorlong and tell your doctor if:
- Are allergic (hypersensitive) to metoprolol, other beta- blockers, or to any of the excipients .
- You have heart rhythm disturbances or cardiac conduction ( ~ second or third degree atrioventricular block or atrial syndrome sick sinus )
- Have untreated heart failure, or are being treated for enhancement of cardiac contractions , or you are in shock caused by heart problems
- You suffer from a narrowing of the blood vessels of the extremities , including violations of the circulation of the blood ( which can cause numbness, pallor or bruising of the digits )
- You have a slow heart rate (less than 50 beats / min . )
- Have low blood pressure.
- Suffer from increased acidity of the blood ( metabolic acidosis) .
- Have severe asthma or chronic obstructive pulmonary disease.
- Being treated with medicinal products in the monoamine oxidase inhibitors (MAOIs ) appropriate (see section Taking other medicines).
- You have heart failure and blood pressure regularly fall below 100 mmHg.
- Use other medications to lower blood pressure , such as verapamil and diltiazem appropriate (see section Taking other medicines).
- Treated with antiarrhythmic drugs , such as disopyramide (see section Taking other medicines).
Take special care with Mekorlong and tell your doctor if:
have asthma .
- Have diabetes ( lowering of blood sugar can be disguised by this product )
- Have pheochromocytoma (high blood pressure caused by a tumor of the adrenal glands ) ,
- Being treated to reduce allergic reactions. Mekorlong can increase your hypersensitivity to the substances you are allergic to and increase the severity of allergic reactions
- Have increased activity of the thyroid gland
( metoprolol may mask manifestations of this disease - increased heart rate, sweating, tremor , restlessness , increased appetite or weight reduction) .
- You suffer from psoriasis (a skin disease with persistent rash ) .
- If you are under anesthesia, surgery , please tell your doctor or dentist that you are taking metoprolol.
- Suffering from impaired circulation ( reduced blood flow to the fingers and toes ) had abnormal cardiac conduction (atrial ventricular block ) .
- You have heart failure, and any of the following :
- A heart attack or angina attacks (chest pain) in the last 28 days.
- Impaired renal or hepatic function.
- You are aged under 40 or over 80 years.
- Diseases affecting the heart valves .
- An increase in muscle mass of the heart.
- Have undergone a heart surgery in the last 4 months.
- Uncompensated heart failure ( class IV NYHA)
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. Do not take Mekorlong if you are already being treated with any of the following :
Medicaments for the treatment of depression , monoamine oxidase inhibitors (MAOI ) . They can enhance the effects in terms of lowering blood pressure .
Other drugs for high blood pressure, such as verapamil and diltiazem (may cause a slow heart rate or to enhance the reduction of blood pressure ) .
Antiarrhythmic drugs such as disopyramide ( may increase the risk of irregular or slow heart rate and worsen heart function).
Sultopride ( increased risk of abnormal heart rhythm).
Before starting treatment with Mekorlong tell your doctor if you are taking or have recently taken any of the following medications :
Following medicinal products may potentiate the effect in lowering blood pressure :
- Cimetidine (for the treatment of peptic ulcer disease ) .
- Hydralazine or clonidine ( medicaments for the treatment of high blood pressure ) .
- Terbinafine ( for fungal infections) .
- Paroxetine , fluoxetine and sertraline ( for depression) .
- Hydroxychloroquine (for the treatment of malaria ) .
- Chlorpromazine, triflupromazine , chlorprothixene ( medications for mental illness) .
- Amiodarone , quinidine and propafenone (used to treat heart rhythm disorders) .
- Diphenhydramine ( antihistamine ) .
- Celecoxib ( for joint and muscle pain ) . The following agents may reduce the effect in terms of lowering of blood pressure :
- Indomethacin ( for joint and muscle pain ) .
- Rifampicin ( an antibiotic).
The following medicines may affect or be affected by metoprolol :
- Other beta- blockers, such as e. contained in eye drops.
- Adrenaline , noradrenaline , or other drugs from the group of so -called sympathomimetics .
- A medicament for treating diabetes (symptoms of decreased blood sugar may be masked ) .
- Lidocaine .
- Reserpine, alpha- methyldopa, guanfacine , cardiac glycosides .
Taking Mekorlong with food and drink
Alcohol may increase the effect of metoprolol with respect to the lowering of blood pressure
Pregnancy and lactation
Ask your doctor or pharmacist before taking any medicine if you are pregnant or planning a pregnancy and breast-feeding . Mekorlong not recommended for use during pregnancy and lactation. Ask your doctor for advice.
Driving and using machines
You may feel fatigue and dizziness while taking Mekorlong . This is more frequently observed with concomitant use of alcohol or after a change in dose or drug. If you notice these symptoms , do not drive or operate machinery.
3 . HOW TO TAKE MEKORLONG
Always take Mekorlong exactly as prescribed by your doctor. If you are not sure, ask your doctor or pharmacist Mekorlong prolonged-release tablets are intended for once-daily dosing . It is recommended that they be taken in the morning . The tablets may be swallowed whole or broken . They should not be chewed or destroyed . The tablets should be swallowed with at least half a glass of water . The usual doses are: High blood pressure (hypertension ):
50 mg once daily. If necessary, the dose may be increased to 100-200 mg once daily.
Angina ( chest pain breakthrough ):
100-200 mg once daily.
Abnormal heart rhythm (arrhythmia ):
100-200 mg once daily.
Prevention after myocardial infarction (heart attack ):
200 mg once daily.
Functional disorders of the heart (palpitations ):
100 mg once daily. If necessary , the dose may be increased to 200 mg once daily.
Prophylaxis of migraine :
100-200 mg once daily.
Always follow your doctor's instructions .
Patients with severely impaired hepatic function:
Need dose adjustment . Always follow your doctor's instructions .
Children and adolescents:
Always use Mekorlong in children and poddrastvashti exactly as directed by your doctor.
If you take more dose Mekorlong
When taking a higher dose than prescribed , immediately contact a doctor !
You may experience the following symptoms : very low blood pressure ( dizziness and fatigue ) , slowed heart rate, irregular heartbeat , shock, cardiac arrest , difficulty breathing , loss of consciousness (even coma), nausea , vomiting, bruising skin.
If you forget to take Mekorlong
If you forget to take your regular dose , do it as soon as you guess, then proceed as usual. Do not take a double dose to make up for a missed dose. If necessary , consult your doctor.
If you stop taking Mekorlong
Do not stop suddenly taking Mekorlong as this may cause worsening of heart failure and increase the risk of heart attack. Change the dose or stop treatment only after consulting your doctor.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4 . POSSIBLE SIDE EFFECTS
Like all medicines, Mekorlong can cause side effects, although not everybody gets them . Immediately discontinue Mekorlong and contact a doctor if symptoms of allergic reactions such as itchy skin rash, redness, swelling of the face , lips, tongue and / or throat, difficulty in swallowing and breathing. This is a serious but very rare . You may need immediate treatment , usually in a hospital . Tell your doctor if you notice any of these side effects or if you notice other effects not listed side effects.
Very common (occurs in more than 1 patient in 10 ):
Weakness and fatigue when standing due to low blood pressure, fatigue.
Common / occurs in less than 1 in 10 , but more than 1 out of 100 patients):
Slow pulse, balance disorder ( very rarely with loss of consciousness ) , cold extremities, palpitations (feeling palpitations ), dizziness , headache , malaise, diarrhea, constipation , abdominal pain , shortness of breath during exercise.
Uncommon (occurs in less than 1 in 100 but more than 1 in 1,000 patients):
Temporary worsening of Symptoms of heart failure, cardiac conduction disorders , fluid retention , chest pain, tingling , cramps , weight gain , depression, poor concentration , insomnia, drowsiness , nightmares , difficulty breathing , rash, increased sweating .
Rare (occurs in less than 1 in 1,000 , but more than 1 in 10 000 patients):
Exacerbation of existing diabetes , nervousness , agitation, visual disturbances , dry or irritated eyes , conjunctivitis , impotence, Peyronie's syndrome ( bending of the penis in a state of erection) , irregular heartbeat , dry mouth , fever , hair loss , changes in liver function tests ) .
Very rare (occurs in less than 1 in 10,000 patients):
Changes in blood cells ( low white or red blood cells) , memory impairment , confusion , hallucinations , mood changes , ringing in the ears, hearing disorders , changes in taste , inflammation of the liver ( hepatitis) , photosensitivity , worsening or onset new psoriasis , muscle weakness , joint pain, tissue damage in the extremities in severe violations of their blood supply. If any of the side effects gets serious, or you notice other effects not listed in this leaflet , please tell your doctor or pharmacist.
5 . STORAGE
At temperatures below 30 ° C.
Keep out of the reach of children.
Mekorlong not use after the expiry date stated on the pack . The expiry date refers to the last day of that month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.
6 . ADDITIONAL INFORMATION
What does Mekorlong
The active ingredient is metoprolol succinate.
- Each prolonged-release tablet Mekorlong 50 mg contains 47.5 mg metoprolol succinate equivalent to 50 mg metoprolol tartrate .
- Each extended release tablet of 100 mg contains Mekorlong 95 mg metoprolol succinate, equivalent to 100 mg metoprolol tartrate .
- Each extended release tablet of 200 mg contains Mekorlong 190 mg of metoprolol succinate equivalent to 200 mg of metoprolol tartrate .
Other ingredients are:
- Tablet core: cellulose, microcrystalline , cellulose , maize starch : glycerol : ethylcellulose , magnesium stearate.
- Coating: Hypromellose : Cellulose, microcrystalline : stearic acid titanium dioxide ( E171 ) .
Mekorlong looks like and contents of pack
Prolonged-release tablets Mekorlong 50 mg, 100 mg and 200 mg are white , oval , biconvex, film-coated tablets , scored on both sides.
Packs containing 10,14,20,28,30,50,50 x1, 56,60,98 or 100 prolonged-release tablets .