LORTANDA table. 2.5 mg. 30 tab

LORTANDA table. 2.5 mg. 30 tab
€ 89.00
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Lortanda contains a drug called letrozole. It belongs to a group of medicines called aromatase inhibitors. It is used for hormonal (endocrine) treatment of breast cancer.
The growth of the breast cancer is often stimulated by estrogens, which are female sex hormones

LORTANDA table. 2.5 mg. 30 tab
 
What is Lortanda and what it is used
What is Lortanda and how it works
Lortanda contains a drug called letrozole. It belongs to a group of medicines called aromatase inhibitors. It is used for hormonal ( endocrine ) treatment of breast cancer.
The growth of the breast cancer is often stimulated by estrogens , which are female sex hormones . Lortanda reduces the amount of estrogen by blocking the enzyme ( " aromatase " ) involved in the formation of estrogens and thus can block the growth of breast cancer in need of estrogen for their growth . As a result , the tumor cells slow or stop their growth and / or spread to other parts of the body.

What is it used Lortanda
Lortanda be used for treatment of breast cancer in women who have gone through menopause , i.e. no menstruation.
It is applicable for the prevention of recurrence of breast cancer. Can be used as a first line therapy after surgical removal of the breast or in five years of treatment with tamoxifen . Lortanda also be used to prevent the spread of the tumor to other parts of the body in patients with advanced diseases .
Ask your doctor if you have any questions about what is the effect of Lortanda and why you are prescribed this medicine.

2 . What you should know before you start taking Lortanda
Follow all instructions of your doctor. They may differ from the general information in this leaflet.

 
Do not take Lortanda :
 If you are allergic (hypersensitive) to letrozole or any of the other ingredients of this medicine (listed in Section 6) ;
 if you still have menstruation , ie if you are in menopause ;
 if you are pregnant ;
 if you are breastfeeding .
 
If any of these apply to you , do not take this medicine and consult your doctor.

Warnings and Precautions
Consult your doctor or pharmacist before you start taking Lortanda :
 if you have severe kidney disease;
 if you have severe liver disease ;
 if you have a history of osteoporosis or bone fractures (see also monitoring your treatment with Lortanda "in section 3 ) .
 
If any of these apply to you, tell your doctor. Your doctor will take this into account during your treatment with Lortanda .

Children and adolescents ( under 18 years)
Children and teenagers should not use this medicine.

The elderly (over 65 years)
This medicine may be used in patients older than 65 years in the same dosage as in younger adult patients.

Other medicines and Lortanda
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Pregnancy, lactation and fertility
You should take Lortanda only when you have gone through menopause. However, your doctor should discuss the use of effective methods of contraception , as you can still have the potential to become pregnant during treatment Lortanda .
You should not take Lortanda if you are pregnant or breast-feeding , as this can harm your child.

Driving and using machines
If you feel dizzy , fatigue, drowsiness or feeling unwell, do not drive or operate any tools or machines until you feel well again .

Lortanda contains lactose
Lortanda contains lactose (milk sugar). If your doctor has told you that you have an intolerance to some sugars , contact your doctor before taking this medicine.

3 . How to take Lortanda
Always take this medicine exactly as prescribed by your doctor or pharmacist. If you are not sure, ask your doctor or pharmacist.
The usual dose is one tablet once daily Lortanda . Adoption of Lortanda every day at the same time will help you not to miss taking your tablet .
The tablet should be taken with or without food and swallowed whole with a glass of water or other liquid.

How long to take Lortanda
Continue to take Lortanda every day as long as you have been told your doctor. You may need to take Lortanda for months or even years. If you have questions about how long to continue taking Lortanda , discuss them with your doctor.

Monitored during treatment with Lortanda
You should not take this medicine under strict medical supervision . Your doctor will monitor your condition to check that the treatment is having the right effect.
Lortanda can cause thinning of the bones or bone loss ( osteoporosis) due to the reduction of estrogen in your body. Your doctor may want to measure your bone density ( a way of monitoring for osteoporosis) before, during and after treatment.

If you take more than you should Lortanda
If you take too many tablets Lortanda , or if someone else accidentally takes your tablets , ask immediately for advice from a doctor or the nearest hospital. Show them your pack of tablets . May require treatment .

If you forget to take Lortanda
If it is almost time for your next dose ( eg 2 to 3 hours) , skip the dose that you have not taken and take the next dose at the regular time.
Otherwise , take the dose as soon as you remember and then take your next dose at the regular time.
Do not take a double dose to make up.

If you stop taking Lortanda
Do not stop taking Lortanda unless your doctor tells you to. See also section above " How long to take Lortanda ."

4 . Possible side effects
Like all medicines, this medicine may cause some side effects, although not everybody gets them.
Most adverse reactions were mild to moderate and generally resolves in a few days to a few weeks of treatment.
Some of the side effects such as . hot flashes , hair loss or vaginal bleeding may be related to lack of estrogen in your body .
This list of side effects should not bother you . You may not experience any of them .
 
Some side effects can be serious .
Rare or uncommon (ie likely to affect between 1 and 100 per 10 000 patients):
 Weakness , paralysis or loss of sensation in part of the body (mainly by hand or foot) , loss of coordination , nausea, difficulty in speaking or difficulty breathing ( symptoms of brain damage, for example . Stroke) ;
 Sudden tightening of chest pain (a symptom of heart disease ) ;
 Difficulty breathing , chest pain , fainting , fast heartbeat, bluish skin or sudden pain in the arm or leg ( possible signs of clot formation ) ;
 Swelling or redness along a vein which is very sensitive and painful to the touch ;
 Highly fever, chills or mouth sores due to infections (absence of white blood cells) ;
 Serious and persistent blurred vision .
 
Tell your doctor immediately if any of these conditions .

 
You should also inform your doctor immediately if you experience any of these symptoms during treatment with Lortanda :
 Swelling mainly of the face and throat (signs of an allergic reaction) ;
 Yellowing of the skin and eyes, nausea, loss of appetite , dark colored urine ( signs of hepatitis) ;
 Rash, skin redness, blistering of the lips, eyes or mouth , skin peeling , fever ( sign of a skin disease ) .
 
Some side effects are very common. These side effects may affect more than 10 out of 100 patients:
 Hot flashes ;
 High cholesterol ( hypercholesterolemia ) ;
 fatigue ;
 Profuse sweating ;
 Pain in bones and joints ( arthralgia) .
 
If any of these effects affect you severely, tell your doctor.

Some side effects are common. These side effects may affect between 1 and 10 in every 100 patients:
 Skin rash ;
 headache ;
 Feeling of dizziness fainting ( malaise ) ;
 Gastrointestinal disorders such as nausea, vomiting, swallowing, constipation , diarrhea ;
 Increase or loss of appetite;
 Muscle pain ;
 Thinning or weakening of the bones ( osteoporosis ), leading in some cases to bone fractures (see also section "Monitoring your treatment with Lortanda " in item 3 ) ;
 Swelling of arms, hands , ankles or feet ( edema) ;
 Depression (depression ) ;
 Weight gain ;
 hair loss ;
 High blood pressure (hypertension) ;
Abdominal pain ;
Dry skin ;
Vaginal bleeding.

If any of these effects affect you severely, tell your doctor.

Other side effects are uncommon. These side effects may affect between 1 and 10 in every 1000 patients:
 Nervous system disorders such as anxiety , nervousness , irritability, dizziness ;
 Memory problems , drowsiness, insomnia ;
 Impairment of sensitivity , especially to the touch ;
 Eye disorders such as blurred vision , eye irritation ;
 Palpitations, rapid heart beat;
 Skin disorders such as itching ( hives) ;
 Vaginal discharge or dryness ;
 Stiffness of the joints ( arthritis) ;
 Chest pain ;
 fever ;
 Thirst , diarrhea, taste , dry mouth ;
 Dryness of mucous membranes ;
 Weight loss ;
 Urinary tract infection , increased frequency of urination ;
 cough;
 Increased levels of enzymes.

If any of these affects you severely, tell your doctor.

If you get any side effects , talk with your doctor or pharmacist. This includes all side effects not listed in this leaflet.

5 . How to store Lortanda
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the carton and blister after "EXP :/ EXP ." The expiry date refers to the last day of the month .
This medicinal product does not require any special storage conditions .
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required . These measures will help to protect the environment.

6 . Package Contents and more information
What does Lortanda
The active substance is letrozole (letrozole). Each tablet contains 2,5 mg letrozole.
The other ingredients are lactose monohydrate, maize starch , hypromellose type 2910 , microcrystalline cellulose , sodium starch glycolate type A , silica , colloidal anhydrous and magnesium stearate in the tablet core and hypromellose 6 Wed , titanium dioxide ( E 171 ), yellow iron oxide ( E 172 ) , macrogol 400 and talc in film-coating (see section 2).

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