LIPOPRES. 40 mg. 30 tablets
LIPOPRES. 40 mg. 30 tablets
Lipopres 40 mg, tablets .. Lovastatin
Drug in one tablet Lipopres 40 mg: Lovastatin 40 mg.
Excipients: pregelatinized starch , microcrystalline cellulose , butylated hydroxyanisole (E 320 ) , magnesium stearate, lactose , E 132.Lekarstveno substance per tablet Lipopres 40 mg: Lovastatin 40 mg. Inactive ingredients: pregelatinized starch , microcrystalline cellulose, butylated (E 320 ), magnesium stearate , lactose, E 132 , E104.Lipopres is available in packs of 30 tablets.
1. LIPOPRES WHAT IS AND WHAT IT IS USED
The active substance of Lipopres tablets Lovastatin . Lovastatin decreases high concentrations of cholesterol and other lipids in the blood.
Lipopres administered for the treatment of:
- Primary hypercholesterolemia ( elevated cholesterol levels ) , high levels of some of the fractions of cholesterol in the blood, in the case of an inadequate response to dietolechenieto ;
- Ischaemic Heart Disease (IHD ) - to slow the progression of coronary atherosclerosis (a process of deposition of lipids in the vessels of the heart and a reduction in elasticity and the road) by lowering cholesterol levels, as part of a comprehensive treatment .
2 . WHAT YOU NEED TO KNOW BEFORE YOU START LIPOPRES
Lipopres not apply to :
- Hypersensitivity to any component of the drug ;
- Active liver disease or persistently elevated liver enzymes ( transaminases) ;
- Pregnancy and lactation .
When taking this medicine, you should consider:
The product is taken under medical supervision !
When treated with Lipopres may be an increase in blood levels of some liver function , but without jaundice or other clinical symptoms. Mild to moderate elevations of these indicators can be observed at the beginning of treatment. These changes are usually transient and did not require interruption of therapy. If the values of liver function exceed more than 3 times the upper limit of the reference values , treatment can be continued or discontinued at the discretion of the physician. Recommended systematic monitoring of these indicators , especially early in treatment . Occurrence of muscle pain is also associated with treatment Lipopres.Tozi problem must be considered in all patients with diffuse muscle tenderness or weakness , and / or marked increase nakreatinfosfokinazata ( an indicator of muscle involvement ) . In serioznozasyagane can reach acute renal failure. In appearance this problem Lipopres treatment should be preustanovi.Da inform the doctor if you develop unexplained muscle Bolkiah weakness, particularly if accompanied by malaise ilitemperatura.Uvedomete doctor if you have liver disease or consume large amounts of alcohol . Your doctor will perform periodic monitoring of liver function during lechenieto.Uvedomete doctor if you have kidney disease . Lipopres therapy should be discontinued in any patient who is seriously ill or there is a risk factor for renal failure due to severe violation of muscle structure and function (rhabdomyolysis), such as severe acute infections , trauma, low blood pressure, major surgery , severe metabolic disturbances and is garchove.Pri uncontrolled patients with rare familial forms of elevated cholesterol (familial hypercholesterolemia ) , Lipopres is less efficient. Probability Lipopres raise some of the indicators of liver function in these patients is golyama.Lipopres only moderately reduces triglycerides ( fraction of lipids in the blood) and is indicated in diseases where elevated triglycerides are a leading symptom.
Lipopres should not be used in children .
Application of Lipopres and intake of food and drink
During treatment with Lipopres , patients should be placed on a diet low in fat.
Before taking any medicines , consult your doctor or farmatsevt.Lipopres be given to women of childbearing age only when such patients less likely to conceive. In pregnancy , the intake of Lipopres should be discontinued .
Before taking any medicines , consult your doctor or pharmacist. No data on the excretion of lovastatin in human milk , and therefore during the treatment with the product feeding to be interrupted .
Driving and using machines
Application of Lipopres not affect the ability to drive or operate mashini.Vazhna information about some of the ingredients of Lipopres ®:
This medicinal product contains lactose, which makes it unsuitable for people with lactase deficiency , galactosemia or glucose / galactose syndrome malabsorbtsiya.Sadarzhashtiyat in the product butylhydroxyanisol an irritant effect on eyes, skin and ligavitsite.Prilozhenie other medicinal products:
Please tell your lekuvagts doctor or pharmacist if you are taking or have recently taken any other medicines , even if they have not been prescribed by your doctor.
During prolonged and high dose combination therapy of Lipopres ® drug immunosuppressive ( cyclosporine) , lowering the levels of blood lipids ( fibrates , niacin ), antibiotics and antifungals ( erythromycin , clarithromycin , itraconazole, ketoconazole) , nefazodone ( medicine to treat depression) or drugs used in AIDS may develop a severe violation of muscle structure and function ( rhabdomyolysis).
During concomitant Lipopres and drugs that reduce blood clotting ( anticoagulants) , prothrombin time ( an indicator of the effect of these drugs ) may be extended . In such patients, prothrombin time should be determined before starting treatment with Lipopres then be monitored regularly . Lipopres , unlike other products for the treatment of impaired lipid metabolism, and has no influence on the effect of digoxin, propranolol and antipyrine at a simultaneous administration of each tyah.Lipopres is effective alone or in combination with drugs that break bile acids . For patients treated with immunosuppressive products whilst receiving Lipopres ® maximum recommended dose is 20 mg daily.
3 . HOW TO TAKE LIPOPRES
Always Lipopres as instructed by your doctor. Initial dose - 20 mg, taken once per evening meal. In mild to moderate hypercholesterolemia (high levels of fats in the blood ), treatment may begin with 10 mg dnevno.Za treatment of coronary artery disease - 20-80 mg daily, taken one or two razpredeleniv priema.Maksimalna daily dose - 80 mg.
Dose adjustments may be made by the physician , depending on the level of lipids in the blood at intervals of not less than 4 weeks. During treatment with Lipopres , patients should be placed on a diet low in maznini.Obiknoveno daily dose Lipopres single daily dose in the evening meal .
The duration of treatment can be determined by the attending physician . Should not be discontinued taking Lipopres without consulting a doctor. After cessation of treatment, usually the level of cholesterol in the blood is increased again .
In patients with severe renal impairment, the use of daily doses above 20 mg should be done under strict supervision of the prescribing physician .
If you have the impression that the effect of Lipopres ® is strong or too weak, talk to your doctor or pharmacist.
If you take more than the prescribed dose Lipopres :
When taking a higher dose than prescribed , immediately contact a doctor !
In overdose, the unused amount is removed by gastric lavage , activated charcoal is administered and the patient is placed in an environment of clean air . Specific treatment of overdosage is missing. In these cases should be monitored liver function .
If symptoms of overdose , immediately contact a doctor!
If you forget to use Lipopres :
In case of failure of the dose should not take extra doses. Product acceptance should continue as usual.
4 . POSSIBLE SIDE EFFECTS
Like all medicines , Lipopres can cause adverse reaktsii.Po majority of adverse reactions during treatment with Lipopres ® are mild and transient. There are (more than 1% of cases) : flatulence , diarrhea, constipation, nausea, dizziness, blurred vision , headache , muscle cramps, muscle pain , skin rashes , abdominal pain . At 0.5-1 % of patients may be monitored fatigue , itching, dry mouth , insomnia , sleep disorder , indigestion and dysgeusia . In individual cases may occur hepatitis , congestive jaundice , vomiting , loss of appetite , tingling and psychiatric disorders , including anxiety, certain immune reactions with skin manifestations , severe skin reactions , scant kosata.Ryadko observed severely impaired muscle structure and function ( rhabdomyolysis).
Rarely observed hypersensitivity - swelling of the face , eyelids, tongue (angioedema) , hives, joint pain , chills, shortness of breath, increased susceptibility to svetlina.Ima messages significantly and held for a long time increases blood levels of liver function.
If you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5 . STORAGE CONDITIONS
Keep out of reach of children . At temperatures below 25 ° C. Do not use after the expiry date stated on the package ! Shelf life : two (2 ) years from date of manufacture.