LENUXIN 10 mg. 28 tablets

Gedeon Richter
LENUXIN 10 mg. 28 tablets
€ 19.00
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What Lenuxin and what it is used
Lenuxin containing escitalopram, a selective inhibitor of serotonin reuptake (SSRIs) and belongs to a group of medicines known as antidepressants.
Lenuxin be used for the treatment of depression, panic disorder, social anxiety disorder (also called social phobia), generalized anxiety disorder and obsessive-compulsive disorder:
Depression is characterized by low / depressed mood, lack of energy, melancholy, feelings of inferiority, sleep disturbance, withdrawal and inability to cope with everyday tasks. Depression can be accompanied by thoughts of suicide. Depressed patients may have symptoms of anxiety;
Panic disorder is characterized by the occurrence of unexpected bouts of pronounced panic or anxiety associated with certain situations or fear of occurrence of new attacks. The reasons provoking panic attacks vary between patients. Attacks are repeated when the patient gets back in the same situation;
Social anxiety disorder, also known as social phobia is characterized by excessive fear of social situations. Patients tend to avoid social situations that may cause them anxiety or discomfort;
OCD is characterized by unwanted thoughts and repetitive behavior.
Lenuksin will alleviate these symptoms and make you feel better.

2. What you need to know before taking Lenuxin
Do not take Lenuxin
if you are allergic to escitalopram or any of the other ingredients of this medicine (listed in section 6). Consult your doctor if you think you may be allergic;
if you take other medicines that belong to a group called MAO inhibitors, including selegiline (used in the treatment of Parkinson's disease), moclobemide (used to treat depression) and linezolid (an antibiotic);
if you are taking other medicines that belong to the group called non-selective monoamine oxidase (MAO) inhibitors, such as phenelzine, isocarboxazid and tranylcypromine, which are also used for the treatment of depression. If you take any of these medications, you need to wait 14 days before you start taking your tablets Lenuksin. After discontinuation of Lenuksin, you must wait seven days before taking any of these medicines;
if born have or have had episodes of irregular heartbeat (identified through ECG study for assessing heart function);
if you are taking medicines for heart rhythm problems or that may affect heart rhythm (see. section 2, "Other medicines and Lenuxin") ";
See "Other medicines and Lenuksin."
Warnings and Precautions
Talk to your doctor, pharmacist or nurse before taking Lenuksin.

Take special care with Lenuxin
if you have or have had heart problems or have recently had a heart attack;
if you have a low heart rate measured at rest and / or know that you have salt deficiency due to prolonged severe diarrhea or vomiting (feeling sick), or use of diuretics (water tablets);
if you feel that your heart rate quickened or become irregular if you get sick, collapse or dizziness on standing up which may indicate abnormal functioning of the heart rhythm.
Please tell your doctor if you have any medical problems

Thoughts of suicide and worsening of depression or anxiety disorder
If you are depressed and / or have anxiety disorders you can sometimes have thoughts of harming or killing themselves. They may be increased when you first start taking antidepressants, since it takes time for all these drugs would act, usually about two weeks but sometimes longer.

More likely to have such thoughts:
If you have previously had thoughts of suicide or self-harm;
If you are a young adult. Information from clinical trials has shown an increased risk of suicidal behavior in young adults (under 25 years) with psychiatric problems who were treated with an antidepressant.
Immediately contact your doctor or go straight to hospital if you have thoughts of harming or killing themselves.
It may find it helpful to tell a relative or close friend that you are depressed or have an anxiety disorder, and ask them to read this leaflet. You might ask them to tell you if they think your depression or anxiety is getting worse, or if they are worried about changes in your behavior.

Children and adolescents
Escitalopram should generally not be used in children and adolescents under 18 years. It is also necessary to know that when they take this class of drugs by patients under 18 have an increased risk of side effects such as suicide attempts, suicidal thoughts and hostility (predominantly aggression, oppositional behavior and anger). However, your doctor may prescribe Escitalopram for patients under 18 because he / she decides that this is in their interest. If your doctor has prescribed escitalopram for a patient under 18 and you wish to discuss this, please visit your doctor again. You should inform your doctor if any of the symptoms listed above appear or worsen when patients under 18 are taking escitalopram. In addition, not seen yet long-term effects in terms of safety concerning growth, maturation, and cognitive and behavioral development acceptance escitalopram in this age group.
As with other drugs used to treat depression or related diseases, the improvement is not achieved immediately. Before you feel any improvement, it may take a few weeks after starting treatment with Lenuksin. Treatment of panic disorder usually takes 2-4 weeks before any improvement is seen. At the beginning of treatment, some patients may experience increased anxiety, which will disappear with continued treatment. Therefore, it is very important that you follow exactly your doctor's instructions and do not stop treatment or to not change your dose without consulting your doctor.
Some patients with manic-depressive illness may enter into a manic phase. This is characterized by unusual and rapidly changing ideas, inappropriate happiness and excessive physical activity. If you experience this, contact your doctor. Symptoms such as restlessness or difficulty to sit or stand in one place can also occur during the first weeks of treatment. Tell your doctor if you experience these symptoms.
Sometimes you may not notice the above symptoms, so it may be helpful to ask a friend or relative to help you monitor for possible signs of change in your behavior.

Tell your doctor or contact your nearest hospital if you have distressing thoughts or feelings, or if any of the above symptoms occur during treatment.
This is especially important:
If you had mania (extremely elevated mood) or hypomania (irritable mood);
If have decreases in sodium in the blood;
If you are treated with electroconvulsive therapy (ECT);
If you have severe liver disease, impaired hepatic function;
If you suffer from renal impairment;
If you suffer from diabetes;
If you have coronary heart disease;
If you have glaucoma;
If you have epilepsy or a history of seizures. Seizures are a potential risk in all antidepressant medications. If seizures occur or increase the frequency of seizures while receiving Lenuksin containing escitalopram, it is important to tell your doctor;
If skin bleeding. There are reports that drugs such Lenuksin can cause increased expression of subcutaneous bleeding (represented for example by increased tendency to bruises). The risk increases if you have a bleeding tendency, or are taking certain medicines that are known to affect the speed of blood clotting;
The risk is also increased if you are taking drugs that affect blood coagulation.
Other medicines and Lenuksin
Tell your doctor, pharmacist or nurse if you are taking, you have recently taken or might take any other medicines, especially in the last 14 days.
Escitalopram and the following medicinal products should not be combined:
elegilin (used to treat Parkinson's disease), moclobemide (used to treat depression);
Linezolid (an antibiotic);
phenelzine, iproniazid, isocarboxazid, nialamide, and tranylcypromine, are also used to treat depression.
Do not take Lenuksin if you are taking medicines for heart rhythm problems or that may affect heart rhythm, such as antiarrhythmics class IA and III, antipsychotics (eg. Derivatives of phenothiazines, pimozide, haloperidol), tricyclic antidepressants, certain antimicrobial products (e. sparfloxacin, moxifloxacin, intravenous erythromycin, pentamidine, antimalarials, particularly halofantrine), some antihistamines (astemizole, mizolastine).
If you have any further questions regarding the above, you should consult your doctor.

Escitalopram and the following medicinal products should be combined carefully:
mefloquine (used to treat malaria) due to a possible risk of a lowered threshold for seizures;
neuroleptics (medicines to treat schizophrenia, psychosis) and antidepressants such as bupropion, due to a possible risk of a lowered threshold for seizures;
flecainide, propafenone and metoprolol (used in cardiovascular diseases), desipramine, clomipramine, and nortriptyline (antidepressants) and risperidone, thioridazine and haloperidol (antipsychotics). It may need the dose of escitalopram to be corrected;
Lithium, a medicine used to treat manic-depressive disorder;
Imipramine and desipramine (both used to treat depression);
If you take both escitalopram and any of these drugs, you should consult your doctor;
Sumatriptan and similar medicines (used to treat migraine);
Tramadol (used against severe pain) increases the risk of side effects. If you experience unusual symptoms while using this combination, you need to ask your doctor;
Cimetidine, lansoprazole and omeprazole (used to treat stomach ulcers) can induce increased blood levels of escitalopram. If you are taking high doses of escitalopram and feel discomfort when you use it with cimetidine or omeprazole, your doctor may decide to reduce your dose of escitalopram;
Medicinal products lowering the levels of potassium and magnesium in the blood;
St. John's wort (Hypericum perforatum - a herbal product used in depressed mood); the risk of side effects may be increased if you are taking escitalopram together with herbal products containing St. John's wort;
Drugs affecting blood coagulation: Oral anticoagulants, drugs such as ticlopidine, and dipyridamole phenprocoumon (these drugs are used to reduce the risk of thrombosis); warfarin (used e.g. for the treatment of blood clots limbs / lungs). The efficacy of oral anticoagulants may be altered and your doctor will probably check the coagulation time of your blood when starting and stopping treatment with escitalopram, to ensure that the anti-coagulant dose is still adequate;
In addition, drugs such as aspirin, non-steroidal anti-inflammatory drugs (drugs used for pain relief), some antipsychotics and tricyclic antidepressants.
If you take both escitalopram and any of these drugs, you should consult your doctor.

Taking Lenuksin food and beverages and alcohol
Lenuksin can be taken with or without food.
Lenuksin not observed to increase the effects of alcohol. However, it is advisable not to drink alcohol during treatment with Lenuksin.

Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, ask your doctor or pharmacist before taking this medicine.
Lenuksin Do not take if you are pregnant or planning to become pregnant or breast-feeding, unless you and your doctor have discussed the risks and benefits arising from this:
The general condition of your newborn can be affected by the use of this group of medicines (antidepressants);
If you take Lenuksin during the last three months of your pregnancy, you should know that these side effects could be seen in your newborn: difficulty breathing, bluish skin, fits, body temperature changes, feeding difficulties, vomiting , low blood sugar, stiff or floppy muscles, vivid reflexes, tremor, jitteriness, irritability, lethargy, constant crying, somnolence and difficulty sleeping. If your newborn baby has any of these symptoms, please contact your doctor immediately;
If used during pregnancy, Lenuksin should not be stopped suddenly.
Make sure your nurse and / or doctor knows you are taking Lenuksin. When taken during pregnancy, especially in the last three months of pregnancy, medicines like Lenuksin can increase the risk of serious conditions of babies, called persistent pulmonary hypertension of the newborn (PBHN), causing shortness of breath and blueness of the baby. These symptoms usually begin during the first 24 hours after the baby is born. If this happens to your baby you should immediately contact your medical nurse and / or doctor.
For citalopram, a drug similar to escitalopram, there is evidence from animal studies that lowers sperm quality. In theory, this can affect fertility, although currently not seen such an impact on people.

Driving and using machines
Although Lenuksin does not cause drowsiness and is not seen to affect the intellect, any psychoactive medicinal product may impair judgment or skills.
You must be careful when driving or operating machinery until you decide how it affects.

Lenuxin contains lactose monohydrate (see. Other ingredients in Section 6).
Lenuxin 10 mg film-coated tablets contain lactose monohydrate 0,53 mg per tablet. If you are told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.

3. How to take Lenuxin
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Lenuxin be taken every day as a single daily dose;
Lenuxin can be taken with or without food. Swallow the tablets with a little water. Do not chew;
If necessary, the tablets may be broken by first placed on a flat surface with the score facing upwards. The tablets may be broken by pushed down at both ends of the tablet, using both index fingers.
Usual dosage
Mature
Depression:
The usual dose is 10 mg daily. The dose may be increased by your doctor. The maximum recommended dose is 20 mg daily.
Panic disorder:
An initial dose of 5 mg in the first week, before increasing to 10 mg daily. Your doctor may increase the maximum dose to 20 mg daily.
Social Anxiety Disorder / Social Phobia:
The usual dose is 10 mg daily. It usually takes 2-4 weeks to achieve symptom relief. Depending on how you feel after you've taken your medicine for some time, your doctor may change the dose of 5 mg and 20 mg daily.
Obsessive-compulsive disorder:
The starting dose is 10 mg once daily. Depending on the individual patient response, dosage may be increased to a maximum of 20 mg per day.
Patients with special risk
In patients with mild to moderate renal impairment does not require dose adjustment. In patients with severely reduced renal function is recommended attention;
It is recommended that patients with liver disease (mild to moderate hepatic impairment) to receive a starting dose of 5 mg daily for two weeks. Your doctor may increase the dose to 10 mg daily. Caution is advised in patients with severely reduced liver function;
Use in children and adolescents under 18 years of age - usually Lenuksin not be used in children and adolescents below 18 years;
Elderly (over age 65) - The recommended starting dose of Lenuksin is 5 mg daily, taken as a single daily dose. The dose may be increased by your doctor to 10 mg daily. Recommended maximum dose to be below 20 mg.

Keep out of reach of children.
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